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Articles 1 - 3 of 3
Full-Text Articles in Medicine and Health Sciences
Cell-Matrix Adhesion In Muscle Development And Disease, Michelle F. Goody
Cell-Matrix Adhesion In Muscle Development And Disease, Michelle F. Goody
Electronic Theses and Dissertations
A variety of diseases, both inherited and acquired, affect muscle tissues in humans. The anchoring of muscle fibers to their surrounding environment is critical for muscle homeostasis. Muscle fibers attach to their microenvironment through cell-matrix adhesion complexes. These anchoring complexes are placed under repeated stress during muscle contraction. Genetic mutations in these complexes weaken the attachment between muscle fibers and their microenvironment, making fibers more susceptible to damage and death. This increased fiber degeneration eventually leads to progressive muscle wasting diseases, known as congenital muscular dystrophies. Although clinical trials are ongoing, there is presently no way to cure the loss …
The Effects Of Phosphatidylserine On Reaction Time And Cognitive Function Following An Exercise Stress, Adam John Wells
The Effects Of Phosphatidylserine On Reaction Time And Cognitive Function Following An Exercise Stress, Adam John Wells
Electronic Theses and Dissertations
Phosphatidylserine (PS) is an endogenously occurring phospholipid that has been shown to have cognition and mood enhancing properties in humans, possibly through its role as an enzyme co-factor in cellular signal transduction. Specifically, PS has been identified as activator of classical isoforms of protein kinase C, an enzyme known to be involved in the growth and differentiation of neural cells, and is therefore thought to play a role in the protection of neurons. The purpose of this study was to examine the effects of supplementation with PS and caffeine on measures of cognition, reaction time and mood prior to and …
Phosphatidic Acid Increases Lean Body Tissue And Strength In Resistance Trained Men, David Williams
Phosphatidic Acid Increases Lean Body Tissue And Strength In Resistance Trained Men, David Williams
Electronic Theses and Dissertations
Phosphatidic Acid (PA) is a natural phospholipid compound derived from lecithin which is commonly found in egg yolk, grains, fish, soybeans, peanuts and yeast. It has been suggested that PA is involved in several intracellular processes associated with muscle hypertrophy. Specifically, PA has been reported to activate protein synthesis through the mammalian target of rapamycin (mTOR) signaling pathway and thereby may enhance the anabolic effects of resistance training. To our knowledge, no one has examined the effect of PA supplementation in humans while undergoing a progressive resistance training program. To examine the effect of PA supplementation on lean soft tissue …