Open Access. Powered by Scholars. Published by Universities.®
Articles 1 - 1 of 1
Full-Text Articles in Medicine and Health Sciences
Binding Pocket Identification And Determination Of Overlapping With Different Software Tools For V8 Protease (1qy6) From Staphylococcus Aureus, Faranak Nadarkhani Dinehkaboudi, Nadimbhai Salimbhai Vahora, Ra'ed Khashan
Binding Pocket Identification And Determination Of Overlapping With Different Software Tools For V8 Protease (1qy6) From Staphylococcus Aureus, Faranak Nadarkhani Dinehkaboudi, Nadimbhai Salimbhai Vahora, Ra'ed Khashan
Discovery Day
Background:
Protein-ligand interactions are critical for biochemical functionality in living organisms, and determining the binding pocket characteristics of a protein is essential for designing drugs that interact with specific protein pockets. Several software tools, such as Deepsite, FTSite, CASTp, and F pocket, are available for identifying these binding pockets.
Objective:
This study aimed to determine the percentage overlap and identify the best binding pocket of V8 Protease (1QY6) from Staphylococcus aureus using different software tools.
Method:
The study retrieved the protease protein's PDB file from the Protein Data Bank and used software programs such as Deepsite, CASTp, and FTsite to …