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Full-Text Articles in Medicine and Health Sciences
Corticosteroids For Pain Relief In Sore Throat: Systematic Review And Meta-Analysis, Gail Hayward, Matthew J. Thompson, Carl J. Heneghan, Rafael Perera, Paul P. Glasziou, Chris B. Del Mar
Corticosteroids For Pain Relief In Sore Throat: Systematic Review And Meta-Analysis, Gail Hayward, Matthew J. Thompson, Carl J. Heneghan, Rafael Perera, Paul P. Glasziou, Chris B. Del Mar
Christopher Del Mar
Objective: To evaluate whether systemic corticosteroids improve symptoms of sore throat in adults and children. Design: Systematic review and meta-analysis. Data sources: Cochrane Central, Medline, Embase, Database of Reviews of Effectiveness (DARE), NHS Health Economics Database, and bibliographies. Outcome measures: Percentage of patients with complete resolution at 24 and 48 hours, mean time to onset of pain relief, mean time to complete resolution of symptoms, days missed from work or school, recurrence, and adverse events. Results: We included eight trials, consisting of 743 patients in total (369 children, 374 adults). 348 (47%) had exudative sore throat, and 330 (44%) were …
Antibiotics For Acute Otitis Media In Children (Review), Sharon Sanders, Paul P. Glasziou, Chris Del Mar, Maroeska Rovers
Antibiotics For Acute Otitis Media In Children (Review), Sharon Sanders, Paul P. Glasziou, Chris Del Mar, Maroeska Rovers
Christopher Del Mar
Background: Acute otitis media (AOM) is one of the most common diseases in early infancy and childhood. Antibiotic use for AOM varies from 56% in the Netherlands to 95% in the USA and Australia. Objectives: To assess the effects of antibiotics for children with AOM. Search strategy: We searched the Cochrane Central Register of Controlled Trials (CENTRAL) (The Cochrane Library, 2008, issue 2) which contains the Acute Respiratory Infections (ARI) Group's Specialized Register; MEDLINE (1966 to June week 4 2008); OLDMEDLINE (1958 to 1965); EMBASE (January 1990 to July 2008); and Current Contents (1966 to July 2008). Selection criteria: Randomised …
Excluding Serious Illness In Feverish Children In Primary Care: Restricted Rule-Out Method For Diagnosis, Matthew J. Thompson, Anthony Harnden, Chris Del Mar
Excluding Serious Illness In Feverish Children In Primary Care: Restricted Rule-Out Method For Diagnosis, Matthew J. Thompson, Anthony Harnden, Chris Del Mar
Christopher Del Mar
Extract: The list of possible diagnoses for febrile children seen in primary care is long. Identifying children who may have a serious illness can be difficult and is at the heart of decisions to prescribe, investigate, and refer to hospital. Serious infections (including pneumonia, meningitis, septicaemia, appendicitis) account for less than 1% of children presenting to primary care, yet they are leading causes of morbidity and mortality in children. One of the key challenges for primary care practitioners is trying to balance the risk of missing a serious disease against unnecessary investigation or referral. The diagnostic process hinges on the …
Has The Investment In General Practice Research Been Worthwhile?, Christopher B. Del Mar, Mieke Van Driel
Has The Investment In General Practice Research Been Worthwhile?, Christopher B. Del Mar, Mieke Van Driel
Christopher Del Mar
Extract: It may be time to invest more in primary care research, including research on clinical conditions Here is s a simple exercise: in the PubMed website (http://www.ncbi.nlm.nih.gov/pubmed), type “The New England Journal of Medicine[Jour] AND Australia[All Fields]”, and you will see that the journal has published about 90 Australian articles since 2000. Scanning through them, you will find that just one includes an Australian general practitioner as an author (Professor John Marley, in 10th author position), for an article describing the large blood pressure trial ANBP2. Repeating this exercise for JAMA (the journal of the American Medical Association) yields …