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Yale University

Theses/Dissertations

Tuberculosis

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Full-Text Articles in Medicine and Health Sciences

A Prospective Cohort Study To Evaluate The Efficacy Of A Peer-Led Tuberculosis Education And Counseling Intervention In Kampala, Uganda, Anna Dawn Baker Jan 2020

A Prospective Cohort Study To Evaluate The Efficacy Of A Peer-Led Tuberculosis Education And Counseling Intervention In Kampala, Uganda, Anna Dawn Baker

Public Health Theses

Tuberculosis (TB) is one of the leading causes of death worldwide and disproportionally burdens low- to middle-income countries (LMICs). Upon initiation of treatment for an active TB diagnosis, universal TB education and counseling (TEC) is recommended to promote knowledge and medication adherence. Though previous studies have shown that there are areas that can be improved when delivering routine TEC, there is limited data on how peer-led TEC can fill these gaps in Kampala, Uganda. Our study evaluated the efficacy of a peer-led TEC intervention among newly diagnosed adults initiating TB treatment in Kampala and assessed capacity for scale-up. We used …


Measuring Tb Stigma In Kampala, Uganda, Amber James Jan 2020

Measuring Tb Stigma In Kampala, Uganda, Amber James

Public Health Theses

Tuberculosis (TB) is one of the leading causes of death worldwide and adversely affects persons living with HIV. TB is a highly stigmatizing disease and has been shown to interfere in household TB contact investigation. The objective of this study was to investigate the severity and characteristics of TB stigma through a multiple methods approach. Quantitative methods involved distributing Van Rie Stigma Scales validated in Southeast to household contacts of Index TB patients during routine household TB contact investigation. Qualitative methods involved interviewing household contacts about their attitudes towards household contact investigation, knowledge of TB transmission and treatment, and perceptions …


Geospatial Analysis Of Drug-Resistant Tuberculosis In Santiago De Cali, Colombia, Oscar Norberto Perales Jan 2020

Geospatial Analysis Of Drug-Resistant Tuberculosis In Santiago De Cali, Colombia, Oscar Norberto Perales

Public Health Theses

Infectious diseases like tuberculosis are undergoing an epidemiological transformation in developing countries such as Colombia and throughout Latin America. Recent economic and social developments may drive heterogeneous burdens of disease in the region, especially in urban settings. Geographic Information Systems (GIS) may allow us to better appreciate the geospatial distributions of TB in these contexts. In this study, we aimed to identify regions in Santiago de Cali facing disproportionate TB burdens and sought to determine whether the distribution of drug resistant TB differed. Additionally, we aimed to identify patient risk factors that could lead to differential drug resistance testing. This …


Predictors Of Incomplete Evaluation Among Pediatric Household Contacts Of Pulmonary Tuberculosis Patients In Kampala, Uganda: A Secondary Analysis, Giyoung Lee Jan 2019

Predictors Of Incomplete Evaluation Among Pediatric Household Contacts Of Pulmonary Tuberculosis Patients In Kampala, Uganda: A Secondary Analysis, Giyoung Lee

Public Health Theses

Background: Contact investigation is an active approach to identifying new TB cases by screening contacts of known patients for symptoms and risk factors. This is particularly important for child contacts of TB patients because young children are at higher risk of progressing to severe disease compared to adults. Moreover, children are unable or unlikely to travel to clinics for evaluation independently, so their access to TB evaluation may depend on the adults in their household.

Objective: To evaluate the association between individual- and household-level characteristics and completion of TB evaluation for children under 15 years.

Setting: Seven public tuberculosis (TB) …


A Study Of The Cutaneous Method Of Von Pirquet And The Percutaneous Method Of Moro And Their Comparison With The Other Tuberculin Tests In The Diagnosis Of Tuberculosis, Fu-Chun (Fu Ching) Yen, Yan Fuqing Jun 1909

A Study Of The Cutaneous Method Of Von Pirquet And The Percutaneous Method Of Moro And Their Comparison With The Other Tuberculin Tests In The Diagnosis Of Tuberculosis, Fu-Chun (Fu Ching) Yen, Yan Fuqing

Yale Medicine Thesis Digital Library

This thesis is based on a comparative study of the Von Pirquet tuberculin skin test and the Moro per cutaneous tuberculin test used in the diagnosis of tuberculosis.