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Yale University

Theses/Dissertations

Diagnosis

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Articles 1 - 4 of 4

Full-Text Articles in Medicine and Health Sciences

Meningitis In Infants ≤60 Days Of Age Diagnosis, Parent Experiences And Potential Improvements In Care And Communication, Eduardo Fleischer Jan 2020

Meningitis In Infants ≤60 Days Of Age Diagnosis, Parent Experiences And Potential Improvements In Care And Communication, Eduardo Fleischer

Yale Medicine Thesis Digital Library

Objectives: The aims of this body of work are several fold. Aim 1: To describe the cerebrospinal fluid (CSF) profile of infants ≤60 days old with bacterial meningitis and characterize the clinical and laboratory features of infants with bacterial meningitis who present with no CSF abnormalities. Aim 2: To evaluate the performance characteristics of the BioFire® FilmArray® Meningitis/Encephalitis panel (ME panel), the only Food and Drug Administration (FDA)-cleared multiplexed panel for the evaluation of CSF samples. Aim 3: To identify themes to be included in a parent-reported outcome measure for febrile infants ≤60 days old and to describe the process …


Pediatric Consultations To Child Protective Services: The Role Of Expert Opinions, Lindsay Kellogg Mcguire Jan 2008

Pediatric Consultations To Child Protective Services: The Role Of Expert Opinions, Lindsay Kellogg Mcguire

Yale Medicine Thesis Digital Library

The purpose of this study was to provide a description of the types of child abuse consultations done by experts at Yale-New Haven Children's Hospital (YNHCH) to Child Protective Services (CPS) in Connecticut, and compare the opinions of the likelihood of child maltreatment of the initial treating physician, CPS, and the child abuse expert. Eligible cases were referred by CPS for expert child abuse consultations at YNHCH between March, 1998 and June, 2005. Abstracted information included demographics, information about the type of injury, and the assessments of the case by the initial treating physician, CPS, and the child abuse expert. …


Serum S-100b As A Potential Biomarker For Meningitis In Febrile Infants: An Interim Analysis, Kelvin C. Lau Jan 2008

Serum S-100b As A Potential Biomarker For Meningitis In Febrile Infants: An Interim Analysis, Kelvin C. Lau

Yale Medicine Thesis Digital Library

The purpose of this study is to identify the utility of serum S-100B levels as a marker for meningitis in febrile infants younger than 3 months of age. All infants younger than 3 months of age who presented to the Pediatric Emergency Department (PED) of Yale-New Haven Children's Hospital and required both a lumbar puncture and venipuncture due to either a confirmed rectal temperature ≥38.0°C or an overall presentation that concerned the responsible physician for possible meningitis and required a lumbar puncture as part of their PED evaluation, were prospectively enrolled. A total of 111 patients participated after a 1.5-year …


Significance Of "Atypia" Found On Needle Biopsy Of The Breast: Correlation With Surgical Outcome, Anika Nina Watson Jan 2007

Significance Of "Atypia" Found On Needle Biopsy Of The Breast: Correlation With Surgical Outcome, Anika Nina Watson

Yale Medicine Thesis Digital Library

Although core needle biopsy has been shown to be effective in diagnosing both benign and malignant mammographically detected lesions in the breast, it has also been shown to underestimate cancer most likely due to sampling error. Since a diagnosis of atypical hyperplasia versus malignancy is based on quantitative factors (which could be affected by an error in sampling), the current recommendation is surgical excision for atypical hyperplasia diagnosed on core biopsy. The purpose of the study was to determine if a subset of patients with atypia diagnosed by core biopsy fit the Breast Imaging Reporting and Data Systems (BI-RADS) Category …