Medicine and Health Sciences Commons^™

Acid Attack: How Escherichia Coli Strains Resist Acid Stress, Lindsey Miller

Honors Theses

The systems used by Escherichia coli to combat heightened levels of acidity within their environment are varied and complex. Four distinct systems used by E. coli to resist acid-induced stress were identified in 2004 by Foster (1), though six now are known today. These systems include the glucose-repressed, glutamate-dependent, arginine-dependent, lysine-dependent, ornithine-dependent, and serine-dependent acid resistance systems. Each system is also known by its corresponding abbreviation, AR1-AR6. What is known about each system varies due to identification date, complexity of the pathway, and amount of research completed. Within this paper, each system will be identified and the pathway defined, combining …

Honoring Neurodiversity As An Occupational Therapist, Haley Munson

Honors Theses

The purpose of this study is to discover if and how current occupational therapists use neurodiversity affirming practices through their work with clients that identify as neurodivergent. Neurodiversity refers to variations in cognitive functioning that are considered normal since no two brains function the same. Occupational Therapists (OTs) frequently work with clients that identify as neurodiverse, including with individuals with diagnoses such as autism, ADHD, dyslexia, and sensory processing disorder. This study uses a qualitative approach with a semi-structured interviews to gain insight into OT’s integration of ND affirming principles into practice. Learning how OT’s implement ND affirming practices will …

Safe Patient Care Act Advocation, Julia Rhodes

Honors Theses

This paper discusses advocating for the Safe Patient Care Act and how it affects people in society. This topic is very relevant because it affects a vast majority of people including nurses, patients, and the healthcare systems as a whole. Methods used to advocate for this bill include grass roots activism, composing and presenting speeches, scheduling and attending meetings, presenting to different nursing school cohorts, collaborating with the Michigan Nurses Association, and participating in hearings held by the Michigan House of Representatives. Results consisted of positive feedback from representatives and their word to vote for the Safe Patient Care Act. …

Loneliness Among College Students, Jaime Benson

Honors Theses

This study investigated the level of loneliness among health-focused scholars in the College of Health and Human Services (CHHS), Western Michigan University to improve student life experience, social opportunities, and support networks. We recruited participants from various CHHS programs using a convenience sampling method, requiring informed consent and program enrollment. The UCLA Loneliness Scale served as our measurement tool, allowing us to compare scores across program backgrounds using independent samples t-tests or non-parametric alternatives. Among 59 participants, 22.0% reported low loneliness levels, 49.1% moderate levels, 25.4% moderately high levels, and 3.4% high levels. Notably, the highest scores emerged in questions …

Anti-Microbial Peptide Screen For Crop Protection, Sydney Chen

Honors Theses

Vestaron currently uses an established and reliable peptide discovery and development research platform, particularly for the development of insecticidal peptides. The platform centers around a proprietary yeast expression system for peptide production (“Vestaron’s yeast expression system"). Vestaron aims to expand their portfolio and provide clean solutions in crop protection using peptide technologies to protect plants not only from insect pests but also microbial pests including phytopathogenic fungi and bacteria. Antimicrobial peptides (AMPs) have been studied extensively. However, it is questionable whether Vestaron’s yeast expression system can express AMPs heterologously. In this study, thirteen promising antimicrobial peptides were selected from literature …

Literature Replication: Insect Gut Cell Isolation Protocols, Sophie Pickelner

Honors Theses

A large problem in science is the lack of literature replication, especially for subjects in which there is little published research. Literature replication is an integral part of the scientific method and is important for validating methods and results of published studies. A study from Nature found that out of 1,500 scientists interviewed, over 70% have been unable to reproduce literature studies and over half of them have been unable to reproduce even their own studies (Baker, 2016). This problem is even more pronounced in the field of biology, with 80% of scientists reporting that they are unable to replicate …

Identification Of Factors Contributing To No-Show And Appointment Cancellation Rates In Outpatient Cardiovascular Services., Sarah Bergman

Honors Theses

Appointment no-shows and same-day cancellations have been an ongoing issue in Bronson outpatient cardiovascular services (CVS). Further investigation was needed and is crucial in identifying barriers to care. Consequences of nonattendance may include negative health outcomes for patients and scheduling and financial burdens for the department. Knowledge of barriers of care is helpful in implementing interventions to encourage patient attendance for the benefit of patients’ health and department revenue. The goal of this project was to identify and analyze trends in no-show and cancellation rates and cancellation reasons given by patients. Doing so allowed for the identification of common barriers …

The Impact Of The Covid-19 Pandemic On New Graduate Nurses And Their Nursing Judgement And Decision Making, Marisa Szydlowski

Honors Theses

The COVID-19 pandemic led to major changes in the field of healthcare. COVID-19 has changed how providers and staff interact with patients and each other, limited access to healthcare in some groups, and led to changes in healthcare education in academia. To date, there has been little research conducted on the pandemic and the effects it had on nursing students. Current literature focuses on the pandemic and how it impacted already practicing and licensed healthcare workers such as registered nurses. Additional research is needed to assess those who were in school during the pandemic. In nursing education, there was a …

The Impact Of The Covid-19 Pandemic On New Graduate Nurses And Their Nursing Judgement And Decision Making, Chase Rosengarten

Honors Theses

The COVID-19 pandemic led to major changes in the field of healthcare. COVID-19 has changed how providers and staff interact with patients and each other, limited access to healthcare in some groups, and led to changes in healthcare education in academia. To date, there has been little research conducted on the pandemic and the effects it had on nursing students. Current literature focuses on the pandemic and how it impacted already practicing and licensed healthcare workers such as registered nurses. Additional research is needed to assess those who were in school during the pandemic. In nursing education, there was a …

The Impact Of Staffing Shortages In Healthcare, Sana Syed

Honors Theses

Healthcare is an industry in which staff is imperative. No matter the advancement of technology, people are always needed to fulfill certain roles that are crucial for the patient’s quality of care and safety. Adequate staffing is a fundamental component of healthcare. As safety is a top priority for patients and healthcare workers, it is important to understand how this is compromised when there is inadequate staffing on the floor. The COVID-19 pandemic significantly reduced retention rates as employees reached burnout during a time of distress and uncertainty. As hospital units were flooded with patients becoming increasingly ill, the safety …

The Impact Of The War In Gaza On Pediatric Mental Health, Noura Warsi

Honors Theses

Due to the military occupation and numerous violent wars that occur in the Gaza Strip, current research depicts that these occurrences not only suscept children to physical harm, but are also detrimental to children’s mental health, causing lasting consequences if left untreated. The purpose of this project is to understand and analyze the impact of the wars, specifically the 2021 war, and the military occupation on Gaza’s pediatric mental health. Unfortunately, children in Gaza, as well as parents, teachers, health care providers, and mental health counselors have the unique problem of navigating mental health crises in children who experience continuous …

Spiritual Care Within The Field Of Healthcare, Summer Sirrine

Honors Theses

This thesis can be interpreted as a fundamental and comprehensive resource that addresses major discussion points of spiritual care (SC) within the healthcare setting. It begins with definition of SC, information surrounding its value within healthcare, the qualifications necessary to practice it, simple yet effective tools and questions to perform SC, as well as acknowledgment of notable barriers and complications, and how those can be dealt with. SC correlates with not only the patient’s physical and mental health, but how it may impact medical practice, depending on how much an individual’s spirituality, religion, etc. affects their life. Healthcare providers should …

Emotional Support Animals On Campus: Relevance, Benefits, And Controversies, Grace Campbell

Honors Theses

This research pertains to Emotional Support Animals (ESAs) on university campuses. It explores the need for ESAs (specifically for college students), differentiates between types of support animals, and discusses benefits and controversies that come along with ESAs on campus. Following this, it sets up a research study that can be used at Western Michigan University relating to student experience with ESA utilization and approval. The study, if performed, would give insight to student experiences, and help the University in supporting the maximum number of students. Emotional support animals have many benefits for college students, including but not limited to, a …

Intimate Partner Violence In Nursing Students: Prevalence And Impact Of Educational Workshop, Sara Michalowski

Honors Theses

Introduction

The overall purpose of this study was to understand the prevalence of intimate partner violence in nursing students and assess the amount of education and knowledge that nursing students have on this topic. In addition, resources were provided to the students. Suggestions for improvement are also provided for the nursing staff and faculty. There is currently little education being provided to nursing students regarding intimate partner violence, which leads to unpreparedness in the nurse role and failure to recognize abusive situations in their personal lives. The qualitative data is limited regarding the prevalence of intimate partner violence in nursing …

Communication Techniques For Nursing Students, Karlee Coddens

Honors Theses

This thesis will discuss the effects nursing preceptors have on nursing students' clinical experience. This thesis will explore multiple factors that negatively impact nursing student’s communication with their preceptors. It has been found that clinical experiences are extremely important for the future of nursing students. However, there is often a communication barrier between nursing students and their preceptors. This barrier can lead to negative outcomes for new nurses entering the field. Strained communication can also create dangerous situations for patients. Students who fear harsh comments or vertical violence may be reluctant to disclose the limitations of their knowledge. We completed …

Inhibiting Effects Of Methyllycaconitine (Mla) On Pnu-282987 Induced Neurogenesis In Blast-Exposed Mouse Retinas, Nastia Zhiyew Chan

Honors Theses

Irreversible vision loss can be caused by retinal damage, disease, or aging. In recent years, the prevalence of ocular damage due to blast trauma has been increasing due to the modernization of warfare. Adult mammalian retinal neurons were previously thought to lack the capacity for regeneration to reverse vision loss, which deemed the effects of many ocular damages permanent. However, recent studies from this lab have shown that PNU-282987, an agonist to the alpha 7 subtype of neural nicotinic acetylcholine receptors, will result in neural regeneration in adult mammalian cells. For this research project, I will be using Methyllycaconitine (MLA), …

Our Voices: Getting To Know Autism, Katherine Rasberry

Honors Theses

This study was done in effort to understand the thoughts and feelings of autistic adults relative to life transitions and resources available. We surveyed key stakeholders; specifically autistic students, but also family/caregivers of adults. Six surveys were created, each based upon different themes: camouflaging, life transitions, managing mental health, overstimulation, social communication, and family and caregiver perceptions. Our surveys were marketed on Western Michigan University’s campus and through social media and are still ongoing. Trends in the data, however, suggest that overall autistics have concerns about how their disabilities impact life in or shortly after college. Many respondents expressed they …

“Exploring The Advantages And Disadvantages Of Universal Electronic Medical Records”, Zachary Mcclenny

Honors Theses

A universal electronic medical record (EMR) is a platform where all of a patient's medical information, history, and data is stored and maintained by providers over time. A universal platform allows all of the medications, tests, procedures, labs, scans, notes, and any other clinical information for that patient to be kept in a record for any provider to view and make changes to while under their care. Although in the United States today, as well as many other countries, EMRs are owned and operated by privately ran businesses and institutions. Only the private institutions that have access to the EMR …

Creation Of Preschool Evaluation For Children Experiencing Sensory Processing Disorders, Mary Vestal

Honors Theses

For our thesis project, we partnered with Dr. Michelle Suarez, the co-director of the Resiliency Center at Western Michigan University. When we first met with her, she informed us about the high rates of expulsion for Kalamazoo preschool students with various regulation challenges relating to sensory processing disorders, regulation, autism, and trauma. In fact, according to the U.S. Department of Health and Human Services, preschool students are expelled at three times the rate of children in K-12 (2022). Additionally, according to the Equal Justice Society, 250 preschool children get suspended or expelled each day nationwide (2021). The article continues to …

Ways To Decrease Risk Of Postpartum Hemorrhage, Madison Holcomb

Honors Theses

Postpartum hemorrhage (PPH) is the leading preventable cause of maternal mortality (Jena et al., 2022). In fact, it accounts for 25% of maternal deaths globally (Cooper et al., 2022). There is a tremendous need for education to the pregnant population There are methods to decrease the risk that needs to be taught to patients. The education on risk factors should be provided in the in the preconception period and throughout pregnancy. There are several components of educational practice that may improve the knowledge of pregnant individuals. The educational components can be divided into implementations during the antenatal period and the …

Creation Of Preschool Evaluation For Children Experiencing Sensory Processing Disorders, Brittney Tuck

Honors Theses

For our thesis project, we partnered with Dr. Michelle Suarez, the co-director of the Resiliency Center at Western Michigan University. When we first met with her, she informed us about the high rates of expulsion for Kalamazoo preschool students with various regulation challenges relating to sensory processing disorders, regulation, autism, and trauma. In fact, according to the U.S. Department of Health and Human Services, preschool students are expelled at three times the rate of children in K-12 (2022). Additionally, according to the Equal Justice Society, 250 preschool children get suspended or expelled each day nationwide (2021). The article continues to …

Case Study - The Outcomes Of Occupational Therapy For An Autistic Teen, Molly Boyle

Honors Theses

This study sought to understand the outcomes of occupational therapy through interviews of a person with autism spectrum disorder (defined below), their family, and an occupational therapist. By interviewing each of these people, this study aimed to examine the impact of occupational therapy on the autonomy and independence of a young adult with autism and his family.

The Effects Of Holistic Modalities On Stress Reduction In Nursing Students Attending School During The Pandemic, Rachel Kamp

Honors Theses

Nursing students tend to experience high levels of stress due to the pressures and demands of nursing school, including exams, clinical, and interactions with professors and preceptors (Labrague et al., 2017). Recently, the COVID-19 Pandemic has created additional stressors. Both mind and body modalities (yoga, meditation, deep breathing etc.) and exercise modalities (running, walking, etc.) are some of many health promoting, stress reducing activities that were proven to be effective in reducing stress in nursing students prior to the pandemic. This study aims to determine if these modalities are still effective now, and how nursing faculty supports stress reduction in …

Asecret Charting And Sensory Processing Disorder - A Tool For Parents And Teachers, Taylor Lerman

Honors Theses

When considering the results of research from this study, the reader should note this specifically applies to elementary school aged students but could be applicable outside of this study for the purpose of added ages. The cumulative ASECRET charts do not explicitly apply to that of a typical child and added disabilities to consider are discussed within the discussion section of research. Conditions left unmentioned should not be considered inapplicable, but for the purpose of this research, discussion points focus on sensory processing and conditions with higher rates of comorbidity to sensory processing compared to others. The purpose of this …

Communication Techniques For Nursing Students, Erin Raby

Honors Theses

This thesis will discuss the effects nursing preceptors have on nursing students' clinical experience. This thesis will explore multiple factors that negatively impact nursing student’s communication with their preceptors. It has been found that clinical experiences are extremely important for the future of nursing students. However, there is often a communication barrier between nursing students and their preceptors. This barrier can lead to negative outcomes for new nurses entering the field. Strained communication can also create dangerous situations for patients. Students who fear harsh comments or vertical violence may be reluctant to disclose the limitations of their knowledge. We completed …

Examination Of Sedentary Behavior And Stress Levels In Undergraduate Students At Western Michigan University, Samantha Putman

Honors Theses

The intention of this research project is to provide a snapshot of current sedentary behavior and stress levels of undergraduate students at Western Michigan University (WMU). This project investigates two variables of interest in current undergraduate students at WMU to understand how much sedentary behavior and stress students are experiencing whilst pursuing their undergraduate degree. Both sedentary behavior and stress are often seen as underlying causes of multiple health issues, which is why they are variables of interest. Understanding these two variables can help the university support aspects of an undergraduate’s life affected by increased stress and sedentary behavior while …

Patient Knowledge Of Family History Of Cardiac Events And Risk Factors: Potential For Increase In Preventative Care Of Cardiovascular Diseases, Joseph Marentette

Honors Theses

The following literature review regards the preventative care of cardiovascular disease (CVD) patients with the knowledge of familial cardiac events and personal cardiac risk factors, particularly in younger populations ranging from ages 18 to 39, and develop potential preventative care measures. CVD is preventable with early reduction of risk factors. People can lower the impact of cardiac risk factors through the modification of their current lifestyle and behavioral habits. However, this is limited to the education and motivation of the person. Primary emphasis must be placed on community education and physician-patient interactions regarding CVD and cardiac risk factors. Physicians need …

Is The Zebrafish Speed Bump Mutant A Mutation In Wee1? And Is It A Complete Loss Of Function?, Nathania Karyadi

Honors Theses

Every cell has to undergo the cell cycle process before it can divide or differentiate. The cell cycle is an error-prone complex process where mutations could happen. This study aimed to characterize the nervous system and blood cells of the speed bump mutant in zebrafish. This study also aimed to do gene characterization of the wee1 CRISPR mutant. The speed bump mutant is due to a mutation in the wee1 gene. Lack of the wee1 gene will cause no Wee1 Kinase, which inhibits the MPF, causing cells to go into mitosis too early. To fulfill these objectives, this study used …

Literature Review On Outer Hair Cell Regeneration And Potential Hearing Restoration, Serena Karlov

Honors Theses

The cochlea is the portion of the inner ear responsible for hearing, containing both the organ of Corti and auditory hair cells. Sound wave vibrations mechanically bend the stereocilia on the three rows of outer hair cells and one row of inner hair cells. These hair cells transduce this mechanical energy into electrical impulses that are relayed from the auditory nerve to the brain, where sounds are processed. In this review I provide an overview of inner ear anatomy, ear physiology, and auditory transduction. I then move on to specifically focus on the importance of outer hair cells, their regeneration, …

The Effect Of Estrogen On Gdnf Production Of Skeletal Muscle In Vitro, Hope Welter

Honors Theses

As life expectancy continues to rise, the number of people over age 65 in the U.S. is increasing. An aging population brings with it impacts on the national health system and associated economic expenditures. As individuals age, the skeletomuscular system suffers reduced function due to disease or conditions such as sarcopenia. Sarcopenia is characterized by muscular atrophy resulting from reduced muscle innervation. Exercise has been linked to prevention of sarcopenia, a suspected result of increased production of glial cell line-derived neurotrophic factor (GDNF). GDNF promotes neuronal survival, regeneration, and the formation of neuromuscular junctions. Therefore, treatments like exercise that increase …