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Virginia Commonwealth University

MCV/Q, Medical College of Virginia Quarterly

Drugs

Publication Year

Articles 1 - 7 of 7

Full-Text Articles in Medicine and Health Sciences

Accidental Hypothermia In Medico-Legal Practice, Keith A. Mant Jan 1970

Accidental Hypothermia In Medico-Legal Practice, Keith A. Mant

MCV/Q, Medical College of Virginia Quarterly

The autopsy findings in 28 cases of fatal hypothermia have been described. Hypothermia, in temperate climates, is one of the complications of longevity. The hypothermic state may be precipitated by a wide range of natural diseases, especially chronic cardiac disease. The classical case of hypothermia may be recognized at post-mortem by the myxoedematous appearance of the patient and the presence of gastric and pancreatic lesions.


Sama-Aωa Student Honors Day: Abstracts Of Scientific Presentations Jan 1970

Sama-Aωa Student Honors Day: Abstracts Of Scientific Presentations

MCV/Q, Medical College of Virginia Quarterly

Medical College of Virginia, May 1969. Summary includes: Mechanism of Baroreceptor-Induced Changes in Heart Rate by Marc D. Thames; Inhibition of Fibroplasia with Lung Implants in the Peritoneal Cavity of the Swiss White Mouse by Kenneth D. Youner; Roentgen Evaluation of the Hepatic Arterial Bed by Parham R. Fox; Effect of Gravity on the Distribution of Blood in the Dog Lung by David H. Bristow, Frank Martorano, and Battina Groome; A Study in CPK Iso-Enzymes by John Elwood Owens; Drug Usage in a Medical Ward by James B. Blitch and Jeffrey Biener; Acquired Absence of Alpha Lipoproteins and Acanthocytosis in …


Cirrhosis: What Is It?, Charles M. Caravati Jan 1968

Cirrhosis: What Is It?, Charles M. Caravati

MCV/Q, Medical College of Virginia Quarterly

An effort has been made to present a panoramic view of cirrhosis. It has been indicated that many agents may initiate an intrahepatic process which may progress to advanced cirrhosis, that the characteristic abnormalities may cause both functional and pathologic multi-system changes, and that these encompass almost every body structure. As the altered structural and physiological changes progress, hepatic decompensation develops, and this often is terminal.


Epidemiology Of Adverse Drug Reactions, Leighton E. Cluff Jan 1967

Epidemiology Of Adverse Drug Reactions, Leighton E. Cluff

MCV/Q, Medical College of Virginia Quarterly

I would like to conclude by citing two rather interesting observations we have made. Three-quarters of all the patients in all our surveillance who have allergic reactions to drugs have had peptic ulcer, ulcerative colitis, or neoplastic disease of the gastrointestinal tract. Of these patients, three-quarters of the drugs producing allergic reactions are administered orally. The rates of allergic reactions to individual drugs in patients with gastrointestinal disease as opposed to those without gastrointestinal disease receiving the same medication, are significantly increased. What the impact is of inflammatory gastrointestinal disease 1) upon the absorption of the drug, 2) upon its …


Some Perspectives On Immunosuppressive Drugs, Robert S. Schwartz Jan 1967

Some Perspectives On Immunosuppressive Drugs, Robert S. Schwartz

MCV/Q, Medical College of Virginia Quarterly

In conclusion, the antimetabolites have proven extremely interesting in the laboratory for the exploration of the mechanism of antibody synthesis and related problems. They have also proven to be extremely useful and interesting materials in the clinic. Whether they are going to replace any other standard forms of therapy, such as the corticosteroids, is, in my view, doubtful. Their use at the moment is experimental and their ultimate place in clinical medicine is by no means settled. They appear to have two important effects in man: 1) Suppression of antibody formation which can be, in many individuals, selective; and 2) …


The Controversy Over Generic Equivalency Of Drugs, Werner Lowenthal Jan 1967

The Controversy Over Generic Equivalency Of Drugs, Werner Lowenthal

MCV/Q, Medical College of Virginia Quarterly

The truth about generic equivalency has not yet been determined. The arguments in the generic equivalency controversy are confounded by names, proprietary (trademark, brand name) as opposed to non-proprietary (generic, branded-generic), yet quality of the products is not necessarily related to any name. The efficacy and not the name of the product is important. The crucial question to ask is whether the product is clinically or therapeutically effective, giving reliable and uniform results.


Pharmacology Of Anti-Anginal Agents, Maurice Mcgregor Jan 1967

Pharmacology Of Anti-Anginal Agents, Maurice Mcgregor

MCV/Q, Medical College of Virginia Quarterly

In conclusion I would like to stress that these observations do not constitute direct evidence of the mechanism whereby the nitrates relieve angina pectoris. It is probable that they are capable of causing some reduction of myocardial oxygen consumption. However, there is increasing indirect evidence which suggests that the site of action of these drugs is principally on the large coronary arteries. Their administration may thus relieve coronary spasm, if this ever causes angina, and more importantly will increase collateral flow into ischemic areas of myocardium when collateral channels have become enlarged. Drugs such as dipyridamole which seem to act …