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Articles 1 - 30 of 81
Full-Text Articles in Medicine and Health Sciences
Contents
MCV/Q, Medical College of Virginia Quarterly
Table of contents for MCV/Q, Medical College of Virginia Quarterly, Winter 1966, Volume One, Number Four.
Further Correlations Of Cell Metabolism And Resistance To Tuberculosis: Studies On Mononuclear Peritoneal Exudate Cells From Mice And Guinea Pigs, John M. Smith Jr., Marvin J. Allison, Brenda Payne
Further Correlations Of Cell Metabolism And Resistance To Tuberculosis: Studies On Mononuclear Peritoneal Exudate Cells From Mice And Guinea Pigs, John M. Smith Jr., Marvin J. Allison, Brenda Payne
MCV/Q, Medical College of Virginia Quarterly
The metabolic activity of mononuclear exudate cells from mice of different strains, and from the guinea pig, have been compared to the rabbit with the aim of relating metabolic activity of these cells to resistance of these species to tuberculosis. The presence of mast cells in the peritoneal exudates of mice was thought to interfere with the dehydrogenation of certain substrates due to the release of histamine. Some experimental evidence presented by the authors seems to support this thesis.
Application Of The Ninhydrin And Alloxan Reactions To Tissue Sections, Nabil A. Azzam, William M. Shanklin
Application Of The Ninhydrin And Alloxan Reactions To Tissue Sections, Nabil A. Azzam, William M. Shanklin
MCV/Q, Medical College of Virginia Quarterly
The ninhydrin and alloxan reactions have been criticized as being nonspecific and unreliable for histochemical studies due to the diffusion, solubility, and fading of their reaction products. This paper presents some modifications of the techniques that appear to render the reactions more reliable for the identification of proteins and peptides possessing terminal α-amino acids. The resulting color complexes are also stable.
A Systematic Approach To The Evaluation And Treatment Of Marital Problems, George Kriegman
A Systematic Approach To The Evaluation And Treatment Of Marital Problems, George Kriegman
MCV/Q, Medical College of Virginia Quarterly
The collaboration of two persons of the opposite sex is a part of the natural sequence of human development and involves the integration of psychodynamic factors and group dynamics. Marriage can be classified into three general types: harmonious, adjusted, and disharmonious. The disharmonious group is classified according to the predominant security operations of the spouse into seven categories. The group dynamics are presented in terms of role functions following Spiegel's (1957) classification of role discrepancies and role resolution, emphasizing the concepts of complementarity and equilibration. The diagnostic evaluation of the personality structure is outlined in terms of the operative level …
Clinicopathological Conference: Abnormal Sex Characteristics And Intracranial Mass, Clark T. Randt, Gerald A. Gildersleeve, Julio H. Garcia
Clinicopathological Conference: Abnormal Sex Characteristics And Intracranial Mass, Clark T. Randt, Gerald A. Gildersleeve, Julio H. Garcia
MCV/Q, Medical College of Virginia Quarterly
Clinicopathlogical conference transcript from the Medical College of Virginia. Discussants include Clark T. Randt, Gerald A. Gildersleeve, and Julio H. Garcia.
Contributors To This Issue
MCV/Q, Medical College of Virginia Quarterly
List of contributors to this issue includes Marvin J. Allison, Nabil A. Azzam, Ali A. Hossaini, George Kriegman, Brenda Payne, William M. Shanklin, John M. Smith, Paul W. Todd, Paul Tournier, and Henry E. Wilson.
Volume One Author Index
MCV/Q, Medical College of Virginia Quarterly
Author index for MCV/Q, Medical College of Virginia Quarterly, Volume One.
The Natural History Of Diabetes, H. St. George Tucker Jr.
The Natural History Of Diabetes, H. St. George Tucker Jr.
MCV/Q, Medical College of Virginia Quarterly
The familial tendency of diabetes has been recognized for centuries. The genetic studies of Pincus and White (1933), Steinberg and Wilder (1952), Post (1962), and others seem to indicate that diabetes is transmitted as a simple autosomal recessive trait. If this is so, it is obvious that the tendency to diabetes must be established at the moment of conception. What does this tendency to diabetes consist of, and what determines when the disease we have called "diabetes" will appear? What is the status of the predisposed individual prior to the onset of overt diabetes?
The Treatment Of Diabetic Acidosis, Thaddeus S. Danowski
The Treatment Of Diabetic Acidosis, Thaddeus S. Danowski
MCV/Q, Medical College of Virginia Quarterly
The patient with diabetes mellitus who becomes unconscious presents a problem in differential diagnosis. We now recognize six possible causes of coma in the diabetic patient. These include the usual diabetic keto-acidosis, and five possible non-ketotic causes: I. Keto-acidosis II. Non-ketotic causes of coma A. Unconsciousness unrelated to diabetes, e.g. barbiturate intoxication, "stroke," uremia B. Hypoglycemia C. Lactic acidosis D. Hypernatremia E. Hyperglycemia
The State Of Insulin In The Blood, Thaddeus E. Prout
The State Of Insulin In The Blood, Thaddeus E. Prout
MCV/Q, Medical College of Virginia Quarterly
Diabetes mellitus has been reviewed as a group of conditions with impaired function of one or more portions of a feed-back system involving the release and utilization of insulin. It is hoped that this may form a useful scheme by which we can study and understand a number of complex metabolic states which we must still collectively refer to as diabetes mellitus.
Insulin Antigenicity, Thaddeus E. Prout
Insulin Antigenicity, Thaddeus E. Prout
MCV/Q, Medical College of Virginia Quarterly
Thus we have seen that evidence of insulin antigenicity in one or more forms is present in most individuals receiving intermediate insulins for six weeks or longer. A number of clinical manifestations of insulin antigenicity and their treatment have been discussed.
Insulin Antagonists, John A. Owen Jr.
Insulin Antagonists, John A. Owen Jr.
MCV/Q, Medical College of Virginia Quarterly
In conclusion, the synalbumin antagonist exists, and may be important in the pathogenesis of human diabetes, but its role has not been proved. The proof will require elucidation of the problem of species specificity, and ability to measure accurately the levels of synalbumin antagonist.
The Pregnant Diabetic, William R. Jordan
The Pregnant Diabetic, William R. Jordan
MCV/Q, Medical College of Virginia Quarterly
At present, more diabetic females of childbearing age are going through pregnancy, and more diabetic children are living beyond maturity. The outlook for the pregnant diabetic has improved greatly but the infant mortality rate of diabetic children remains relatively high. My remarks are based on observations on 105 pregnant diabetics from my private practice.
The Contractile Fine Structure Of Vertebrate Smooth Muscle, Hans H. Weber, J. C. Rüegg
The Contractile Fine Structure Of Vertebrate Smooth Muscle, Hans H. Weber, J. C. Rüegg
MCV/Q, Medical College of Virginia Quarterly
About 30 years ago, Ernst Fischer introduced a new approach to muscle research by comparing the fine structure, and the function of the contractile mechanism of smooth and striated muscle. At that time (Fischer, 1936a and b; 1938) he systematically and successfully investigated the total, the intrinsic, and the form birefringence of smooth muscles and compared his results with analogous data concerning the contractile structure (Noll and Weber, 1935) and the oriented actomyosin threads (Weber, 1935) of skeletal muscle. These investigations were especially important because the birefringence of all muscles is based on its contractile structure and functional state, and …
Latency Relaxation: A Brief Analytical Review, Alexander Sandow
Latency Relaxation: A Brief Analytical Review, Alexander Sandow
MCV/Q, Medical College of Virginia Quarterly
In this report I review certain aspects of the research on the latency relaxation (LR), the minute relaxation of a stimulated muscle that occurs during the latter half of the latent period, i.e., just prior to the onset of contraction (e.g., Sandow, 1944). The first part of my discussion will be historical, dealing with the early, mostly descriptive work on the LR, and then I shall present a more analytically oriented attempt to indicate the significance of the LR in relation to certain aspects of the response of a muscle to stimulation.
Some Effects Of Extreme Shortening On Frog Skeletal Muscle, Sibyl F. Street, Michael N. Sheridan, Robert W. Ramsey
Some Effects Of Extreme Shortening On Frog Skeletal Muscle, Sibyl F. Street, Michael N. Sheridan, Robert W. Ramsey
MCV/Q, Medical College of Virginia Quarterly
We have established that the sarcolemma of frog skeletal muscle is so firmly tied in at each sarcomere level near the M line, as well as near the Z line, that it is thrown into folds or festoons when the fibers shorten. The attachment is not broken even when the fibers shorten to 25% of optimum tension length. Such extreme shortening affects both the morphology and physiology of the muscle; the morphological change seems to be limited to the myofilaments. The physiological effects in frog sartorius muscle include an increase in resting oxygen consumption and changes in the relation between …
Cholinergic Responses Of Schistosoma Mansoni, Ernest Bueding
Cholinergic Responses Of Schistosoma Mansoni, Ernest Bueding
MCV/Q, Medical College of Virginia Quarterly
It is concluded that the use of pharmacological agents can provide opportunities to recognize and define similarities and differences in the mechanisms of transmission of nerve impulses in the parasite and the mammalian host. Such studies contribute to better understanding of comparative physiology and of the mode of action of antiparasitic drugs.
Comments On Intracellular Studies Of Presynaptic Inhibition, Alfred J. Szumski
Comments On Intracellular Studies Of Presynaptic Inhibition, Alfred J. Szumski
MCV/Q, Medical College of Virginia Quarterly
The use of intracellular electrodes, e.g., (micropipettes), in electrophysiological studies of the central nervous system, has enhanced our understanding of the basic function of the nervous system. The purpose of this paper is to review a study in which this microtechnique was successfully employed in the spinal cord.
Recollections Of Professor Otto Meyerhof, Chalmers L. Gemmill
Recollections Of Professor Otto Meyerhof, Chalmers L. Gemmill
MCV/Q, Medical College of Virginia Quarterly
Professor Meyerhof's laboratory represented the Institute approach with all of the workers devoting their attention to the several aspects of the single problem of muscle metabolism. The number of papers (Meyerhof, 1930) and the great contributions from this laboratory represent the results of the dominant personality of one man. The tributes (Nachmansohn, 1950) paid to him in 1950 were published in Metabolism and Function. Comparable tributes are now being given to Dr. Fischer upon his retirement.
Clinicopathological Conference: Complications Of Rheumatoid Arthritis, P. Franklin Mullinax, R. Page Hudson Jr.
Clinicopathological Conference: Complications Of Rheumatoid Arthritis, P. Franklin Mullinax, R. Page Hudson Jr.
MCV/Q, Medical College of Virginia Quarterly
Clinicopathlogical conference transcript from the Medical College of Virginia. Discussants include P. Franklin Mullinax and R. Page Hudson.
The Patient Has The Floor, Alistair Cooke
The Patient Has The Floor, Alistair Cooke
MCV/Q, Medical College of Virginia Quarterly
Address given before the Annual Convocation of the Mayo Graduate School of Medicine, Rochester, Minnesota, on May 28, 1965.
Effects Of Salmonella Vaccination On Metabolism And Resistance To Infection Of Rabbit Peritoneal Cells, Marvin J. Allison, Enrique Gerszten, Blanca Sanchez
Effects Of Salmonella Vaccination On Metabolism And Resistance To Infection Of Rabbit Peritoneal Cells, Marvin J. Allison, Enrique Gerszten, Blanca Sanchez
MCV/Q, Medical College of Virginia Quarterly
Salmonella vaccine caused a depression of metabolism of peritoneal exudate cells from rabbits. This effect was associated with a depression in resistance of rabbits to infection with C. albicans. This depression in metabolism is similar to the one previously noted following BCG vaccine and associated with a depression in resistance to tuberculosis.
Mcv/Q, Medical College Of Virginia Quarterly, Vol. 2 No. 4
Mcv/Q, Medical College Of Virginia Quarterly, Vol. 2 No. 4
MCV/Q, Medical College of Virginia Quarterly
No abstract provided.
Medical Manpower: The Medical Auxiliary, Harold I. Nemuth
Medical Manpower: The Medical Auxiliary, Harold I. Nemuth
MCV/Q, Medical College of Virginia Quarterly
Discussion based on The Assistant Medical Officer. The Training of the Medical Auxiliary in Developing Countries by E. F. Rosinski and F. J. Spencer. University of North Carolina Press. 1965. The current problem which Drs. Rosinski and Spencer have sharply delineated, is the provision of adequate medical care for all the people not only in the developing countries, but here in our so-called "well-developed" society. With or without Medicare the health needs of 190 million Americans increase daily with woefully disproportionate growth in the medical manpower needed to meet these needs. Whatever few failings may be attributed to the Assistant …
Volume Two Author Index
MCV/Q, Medical College of Virginia Quarterly
Author index for MCV/Q, Medical College of Virginia Quarterly, Volume Two.
Problems In The Insulin Dependent Diabetic, Clay T. Gardner Jr.
Problems In The Insulin Dependent Diabetic, Clay T. Gardner Jr.
MCV/Q, Medical College of Virginia Quarterly
It is often useful for the physician to classify diabetes as stable or unstable. Maturity-onset diabetes is usually stable, and its management is not difficult, provided the patient is interested and cooperative. Tendency to obesity, relative insensitivity to insulin, and absence of ketosis are characteristic of such patients. Relative insensitivity to insulin does not imply unresponsiveness, but rather that the blood sugar is not overly labile and does not fall sharply in response to exercise or injected insulin. Many patients with such insensitivity to insulin are adequately managed on diet, alone or in combination with the oral hypoglycemic agents. When …
The Natural History Of Diabetic Retinopathy, Guy H. Chan
The Natural History Of Diabetic Retinopathy, Guy H. Chan
MCV/Q, Medical College of Virginia Quarterly
Diabetic retinopathy is a common and increasing cause of blindness. The higher incidence of retinopathy is related to the longer survival of the diabetic patient. The etiology of diabetic retinopathy remains unknown. However, two varieties appear to exist: Type I retinopathy, characterized by a slowly progressive course and ophthalmoscopic findings of microaneurysms, round hemorrhages, and waxy exudates; and Type II retinopathy, associated with a more rapid loss of vision, in which the main findings are venous engorgement, vascular proliferation, connective tissue condensation, and recurrent vitreous hemorrhages. Both types may result in retinitis proliferans and blindness. In the proliferative (Type II) …
Rate Of Diffusion Of Radioactive Ions In Gels, Thomas C. Smith, Addison D. Campbell, Ernst G. Huf
Rate Of Diffusion Of Radioactive Ions In Gels, Thomas C. Smith, Addison D. Campbell, Ernst G. Huf
MCV/Q, Medical College of Virginia Quarterly
A simple gel-to-gel method is described for the estimation of diffusion coefficients (D) of radio-isotopic chemicals. "Cold" and "hot" gel cylinders, enclosed in small hypodermic syringes with their needle ends cut off, were carefully joined together, and diffusion was allowed to proceed for several hours. Slices of gels were then obtained for counting of activities. Application of the classical theory of diffusion permitted calculations of D values.
Inappropriate Antidiuresis: Examples Of An Hyponatremic Syndrome Resembling Exogenous Vasopressin Administration In Man, Eugene L. Klingler, Joseph H. Magee, John D. Bower, Richard H. Kirkland, Ruben G. Lancestremere
Inappropriate Antidiuresis: Examples Of An Hyponatremic Syndrome Resembling Exogenous Vasopressin Administration In Man, Eugene L. Klingler, Joseph H. Magee, John D. Bower, Richard H. Kirkland, Ruben G. Lancestremere
MCV/Q, Medical College of Virginia Quarterly
We have reviewed some of the features of hyponatremic syndromes, unassociated with sodium retention and edema, but associated with primary water retention. The syndromes were probably caused by excessive vasopressin activity, in the presence of normal circulatory, renal and adreno-cortical function. Underlying diseases, including bronchogenic carcinoma, head injury, and tuberculous meningitis, illustrated the diverse etiologic bases of this condition.
Mcv/Q, Medical College Of Virginia Quarterly, Vol. 2 No. 1
Mcv/Q, Medical College Of Virginia Quarterly, Vol. 2 No. 1
MCV/Q, Medical College of Virginia Quarterly
No abstract provided.