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A 6-Month Randomised Controlled Trial Investigating Effects Of Mediterranean-Style Diet And Fish Oil Supplementation On Dietary Behaviour Change, Mental And Cardiometabolic Health And Health-Related Quality Of Life In Adults With Depression (Helfimed): Study Protocol, Dorota M. Zarnowiecki, Jihyun Cho, Amy Wilson, Svetlana Bogomolova, Anthony Villani, Catherine Itsiopoulos, Theo Niyonsenga, Kerin O'Dea, Sarah Blunden, Barbara J. Meyer, Leonie Segal, Natalie Parletta Jan 2016

A 6-Month Randomised Controlled Trial Investigating Effects Of Mediterranean-Style Diet And Fish Oil Supplementation On Dietary Behaviour Change, Mental And Cardiometabolic Health And Health-Related Quality Of Life In Adults With Depression (Helfimed): Study Protocol, Dorota M. Zarnowiecki, Jihyun Cho, Amy Wilson, Svetlana Bogomolova, Anthony Villani, Catherine Itsiopoulos, Theo Niyonsenga, Kerin O'Dea, Sarah Blunden, Barbara J. Meyer, Leonie Segal, Natalie Parletta

Faculty of Science, Medicine and Health - Papers: part A

Background: Modern diets, characterised by excess consumption of processed foods, are accompanied by an epidemic of chronic diseases. Cardiovascular disease and depression carry a large burden of disease and often occur together. Poor dietary patterns have been identified as an independent risk factor for depression while healthy diets with minimally processed food are protective. Traditional Mediterranean diets have been shown to reduce risk of cardiovascular disease; however there is a need for clinical trials in people with depression. This paper reports the study protocol of a Mediterranean-style diet intervention conducted in adults with self-reported depression. Methods/design: HELFIMED is a parallel …


Rethinking Metabotropic Glutamate Receptor 5 Pathological Findings In Psychiatric Disorders: Implications For The Future Of Novel Therapeutics, Kelly A. Newell, Natalie Matosin Jan 2014

Rethinking Metabotropic Glutamate Receptor 5 Pathological Findings In Psychiatric Disorders: Implications For The Future Of Novel Therapeutics, Kelly A. Newell, Natalie Matosin

Faculty of Science, Medicine and Health - Papers: part A

Background Pharmacological modulation of metabotropic glutamate receptor 5 (mGluR5) is of marked interest as a novel therapeutic mechanism to treat schizophrenia and major depression. However, the status of mGluR5 in the pathophysiology of these disorders remains unknown. Discussion The majority of studies in the schizophrenia post-mortem brain indicate that total mGluR5 expression is unaltered. However, close examination of the literature suggests that these findings are superficial, and in actuality, a number of critical factors have not yet been considered; alterations may be highly dependent on brain region, neuronal population or molecular organisation in specific cellular compartments. A number of genetic …


Food Groups And Fatty Acids Associated With Self-Reported Depression: An Analysis From The Australian National Nutrition And Health Surveys, Barbara J. Meyer, Nithin Kolanu, David A. Griffiths, Ben Grounds, Peter R. C Howe, Irene A. Kreis Jan 2013

Food Groups And Fatty Acids Associated With Self-Reported Depression: An Analysis From The Australian National Nutrition And Health Surveys, Barbara J. Meyer, Nithin Kolanu, David A. Griffiths, Ben Grounds, Peter R. C Howe, Irene A. Kreis

Faculty of Science, Medicine and Health - Papers: part A

Objective The aim of this study was to explore the associations between incidence of depression and dietary intakes of foods and fatty acids in adult Australians. Methods Data from the 1995 Australian National Nutrition Survey (NNS), the 1995 Australian National Health Survey (NHS) and an updated fatty acid database were merged and the 24-h fatty acid intakes were calculated for the 10 986 adult participants ages 18 to 79 y in the 1995 NNS. The merged data set was used to run a logistic regression with depression as the response variable and the food groups and calculated fatty acid values, …


Improvement Of Major Depression Is Associated With Increased Erythrocyte Dha, Barbara J. Meyer, Brin F. S Grenyer, Trevor Crowe, Alice J. Owen, Elizabeth M. Grigonis-Deane, Peter R.C Howe Jan 2013

Improvement Of Major Depression Is Associated With Increased Erythrocyte Dha, Barbara J. Meyer, Brin F. S Grenyer, Trevor Crowe, Alice J. Owen, Elizabeth M. Grigonis-Deane, Peter R.C Howe

Faculty of Science, Medicine and Health - Papers: part A

The aim of this study was to determine if changes in omega-3 polyunsaturated fatty acid status following tuna oil supplementation correlated with changes in scores of depression. A total of 95 volunteers receiving treatment for major depression were randomised to consume 8 × 1 g capsules per day of HiDHA (2 g DHA, 0.6 g EPA and 10 mg Vitamin E) or olive oil (placebo) for 16 weeks, whilst undergoing weekly counseling sessions by trained clinical psychologists using a standard empirically validated psychotherapy. Depression status was assessed using the 17 item Hamilton rating scale for depression and the Beck Depression …


The Longitudinal Relationship Between Depression Symptoms And Disability For Older Adults: A Population-Based Study, Chun-Min Chen, Judy Mullan, Yung-Yu Su, David Atherton Griffiths, Irene Kreis, Herng-Chia Chiu Jan 2012

The Longitudinal Relationship Between Depression Symptoms And Disability For Older Adults: A Population-Based Study, Chun-Min Chen, Judy Mullan, Yung-Yu Su, David Atherton Griffiths, Irene Kreis, Herng-Chia Chiu

Graduate School of Medicine - Papers (Archive)

Background. Although depressive symptoms in older adults are common, their relationship with disability and the influence of disability on the development of depressive symptoms over time is not well understood. This longitudinal study investigates the change trajectories of both depressive symptoms and disability, as well as their associations over time. Methods. Participants included 442 community-dwelling older adults living in Taiwan, aged 65 years or older, who completed six waves of survey interviews. Depression was scored with the Short Psychiatric Evaluation Schedule and disability with the instrumental and physical activities of daily living measure during each consecutive data collection wave. The …


Nutrition Status Of Primary Care Patients With Depression And Anxiety, Adrienne K. Forsyth, Peter G. Williams, Frank P. Deane Jan 2012

Nutrition Status Of Primary Care Patients With Depression And Anxiety, Adrienne K. Forsyth, Peter G. Williams, Frank P. Deane

Faculty of Health and Behavioural Sciences - Papers (Archive)

The objective of this study was to evaluate the nutrition status of people referred to a nutrition and physical activity program for the management of mental health in a general practice.


Study Protocol: A Randomized Controlled Trial Of A Computer-Based Depression And Substance Abuse Intervention For People Attending Residential Substance Abuse Treatment, Peter J. Kelly, Frances Kay-Lambkin, Amanda Baker, Frank P. Deane, Adam C. Brooks, Alexandra Mitchell, Sarah Marshall, Meredith Whittington, Genevieve A. Dingle Jan 2012

Study Protocol: A Randomized Controlled Trial Of A Computer-Based Depression And Substance Abuse Intervention For People Attending Residential Substance Abuse Treatment, Peter J. Kelly, Frances Kay-Lambkin, Amanda Baker, Frank P. Deane, Adam C. Brooks, Alexandra Mitchell, Sarah Marshall, Meredith Whittington, Genevieve A. Dingle

Faculty of Health and Behavioural Sciences - Papers (Archive)

"Background: A large proportion of people attending residential alcohol and other substance abuse treatment have a co-occurring mental illness. Empirical evidence suggests that it is important to treat both the substance abuse problem and co-occurring mental illness concurrently and in an integrated fashion. However, the majority of residential alcohol and other substance abuse services do not address mental illness in a systematic way. It is likely that computer delivered interventions could improve the ability of substance abuse services to address co-occurring mental illness. This protocol describes a study in which we will assess the effectiveness of adding a computer delivered …


Trajectories Of Depression And Their Relationship With Health Status And Social Service Use, Chun-Min Chen, Judy Mullan, David Griffiths, Irene A. Kreis, Tzuo-Yun Lan, Herng-Chia Chiu Jan 2011

Trajectories Of Depression And Their Relationship With Health Status And Social Service Use, Chun-Min Chen, Judy Mullan, David Griffiths, Irene A. Kreis, Tzuo-Yun Lan, Herng-Chia Chiu

Graduate School of Medicine - Papers (Archive)

This longitudinal study was conducted between 1994 and 2004 in a cohort of Southern Taiwan community-living elderly residents. The study aims to explore the trajectories of depression and how these patterns differed between respondents who survived and those who died during data collection phases; this study also investigated how health status change and health/social service use predicted the different trajectories of depression. Eight hundred and ten participants had completed all six waves of the survey or were followed-up at each wave until death in the prospective study in Kaohsiung City. Depressive symptoms were evaluated by the Short Psychiatric Evaluation Schedule …


Do Pregnant Women And Those At Risk Of Developing Post-Natal Depression Consume Lower Amounts Of Long Chain Omega-3 Polyunsaturated Fatty Acids?, Victoria F. Cosatto, Paul L. Else, Barbara J. Meyer Jan 2010

Do Pregnant Women And Those At Risk Of Developing Post-Natal Depression Consume Lower Amounts Of Long Chain Omega-3 Polyunsaturated Fatty Acids?, Victoria F. Cosatto, Paul L. Else, Barbara J. Meyer

Faculty of Health and Behavioural Sciences - Papers (Archive)

The aims were to compare intakes of long chain omega-3 polyunsaturated fatty acid (LC n-3 PUFA) in pregnant and non-pregnant women in Australia and to compare these intakes to the Australian National Nutrition Survey of 1995 (NNS95) [1] and to determine if the LC n-3 PUFA intakes differed in women who may be ‘at risk’ compared with women ‘not at risk’ of developing post-natal depression (PND). A validated LC n-3 PUFA food frequency questionnaire and pregnant women’s Edinburgh Postnatal Depression Scale (EPDS) scores were used. LC n-3 PUFA intakes were comparable to the NNS95 but did not differ due to …


Ecstasy (Mdma) And Its Relationship With Self Report Depression, Anxiety And Schizotypy, Lisa Woods, Emma Barkus Jan 2010

Ecstasy (Mdma) And Its Relationship With Self Report Depression, Anxiety And Schizotypy, Lisa Woods, Emma Barkus

Faculty of Health and Behavioural Sciences - Papers (Archive)

Abstract. Aims: The relationship between ecstasy and affective psychological symptoms are still subject to debate. We aimed to examine the relationship between Ecstasy use and self-report depression, anxiety and schizotypy. Design: Data were collected via structured remote self-report questionnaires. Participants: Participants were split into three groups: a control group with no ecstasy use, a light ecstasy user group (<50 >times), and a heavy ecstasy user group (>50 times). Measurements: Amount and patterns of ecstasy use were recorded, the Beck Depression Inventory (BDI), and Beck Anxiety Inventory (BAI) measured depression and anxiety respectively, and schizotypal traits were measured using the …


The Relation Of Early Environmental Experience To Shame And Self-Criticism: Psychological Pathways To Depression, Karin Sandquist, B. F. S. Grenyer, Peter Caputi Jan 2009

The Relation Of Early Environmental Experience To Shame And Self-Criticism: Psychological Pathways To Depression, Karin Sandquist, B. F. S. Grenyer, Peter Caputi

Faculty of Health and Behavioural Sciences - Papers (Archive)

Self-criticism has been identified as a particularly malignant personality variable that confers vulnerability for the development of depression. Although impressive literature on depressive symptoms and the personality variable self-criticism exists, few studies have examined the origins of a self-critical style and little is currently known as to how the self-conscious affect of shame may impact this link. The aim of this study was to test a more comprehensive path model of depressive symptoms. The proposed model suggested that self-criticism originates from a parental style characterised by low parental warmth and high parental control, with self-criticism and shame representing mediating variables …


Depression And Quality Of Life In Cancer Survivors: Is There A Relationship With Physical Activity?, Nancy Humpel, Donald Iverson Jan 2007

Depression And Quality Of Life In Cancer Survivors: Is There A Relationship With Physical Activity?, Nancy Humpel, Donald Iverson

Faculty of Health and Behavioural Sciences - Papers (Archive)

Background Evidence is growing on the benefit of physical activity to improve well-being following a cancer diagnosis. This study examined changes in physical activity from pre to post diagnosis and explored this relationship with quality of life and depression. Methods Participants were recruited by posters and by letter of invitation. The questionnaire was completed by 59 prostate and 32 breast cancer survivors. Results Physical activity decreased by 72 minutes per week from pre to post diagnosis, although 20.9% reported having increased activity post diagnosis. Over 30% were considered depressed. Breast cancer participants who increased physical activity post diagnosis reported higher …


Depression In The Patient With Copd, Ian G. Wilson Jan 2006

Depression In The Patient With Copd, Ian G. Wilson

Graduate School of Medicine - Papers (Archive)

This paper explores the recent literature surrounding comorbid depression and COPD. The literature reveals a high prevalence of depression in patients with COPD and some evidence that the depression is a result of the disease. The literature highlights the negative impact of depression on quality of life and a possible impact on mortality. Depression also negatively impacts on compliance and smoking cessation. Treatment of depression in COPD, particularly by cognitive behavioral therapy, has positive impact on quality of life. Tricyclic antidepressants have a positive impact on mood and COPD, but side effects limit their use. The advent of the new …


Asthma And Depression: A Pragmatic Review Of The Literature And Recommendations For Future Research, Melissa Opolski, Ian Wilson Jan 2005

Asthma And Depression: A Pragmatic Review Of The Literature And Recommendations For Future Research, Melissa Opolski, Ian Wilson

Graduate School of Medicine - Papers (Archive)

Background: Although the association between asthma and psychosocial factors has long been recognised, it is only in the last decade that the impact of coexisting asthma and depression has become the focus of considerable research interest. However, the findings so far have been confusing and often contradictory. This paper sets out a methodical review and appraisal of the literature to date, including suggestions for future research. Method: PubMed and PsycINFO databases were used to search for English-language articles relating to asthma and depression research. The resulting articles were then reviewed and summarised, creating a report that was used to develop …