Medicine and Health Sciences Commons^™

A Mechanical And Histological Study Of Functionally Graded Hydroxyapatite Implant Coatings, Suzanne Kemp Coco

Theses and Dissertations (ETD)

Ever since Dr. Brånemark discovered that titanium was biocompatible with bone, extensive research has been done to improve the osseointegration of dental implants. As advances in medicine continue, the average life span of the population is ever increasing. Today, people of all ages are investing more money and time into dental treatment than ever before. Patients are becoming more educated on dental treatment options and expect the best treatment possible. As a result, the replacement of missing teeth with implants is becoming more and more commonplace in dental practices.

The purpose of the present study is to evaluate bone-implant interaction …

Silver Doped Hydroxyapatite Coating On Titanium Surfaces And Its Effect On Early Bone Response And Osseointegration, Nicole Besu

Theses and Dissertations (ETD)

The clinical success of dental implants is determined mostly by surface properties of implants and interactions with surrounding tissues. Furthermore, clinical success of dental implants is directed by implant surfaces and bone cell responses that promote osseointegration and long-term stability. Hydroxyapatite (HA)-coated Titanium (Ti) implants have been widely used due to its effect on bone response. However, microbial infection is common. One material known to have anti-microbial properties is silver (Ag). However, the effects Ag has on osteoblastic activity as well as decrease bacterial load has yet to be determined.

In this study, the effect of Ag-doped HA coatings on …

Trabecular Calcium Phosphate Scaffolds For Bone Regeneration, Mark Ryan Appleford

Theses and Dissertations (ETD)

Bone tissue engineering represents a strategy for the repair or regeneration of damaged bone in the body. The science underlying this clinical therapy bridges the traditional fields of cell biology, materials science and mechanical engineering with the aim to identify how cells behave on physiologically relevant materials with natural mechanical stimuli. The objectives of this research were to develop and characterize calcium phosphate ceramic scaffolds matched to the local architecture of natural trabecular bone and to apply tissue engineering strategies for the study of cell behavior in both in vitro and in vivo models.The specific role of environment on cell …

Evaluation Of Osseointegration Between Two Different Modalities Of Hydroxyapatite Implant Surface Coatings: Plasma Sprayed Ha Coated Implants And Electrophoresis Deposited Nano Ha Coated Implants, Audrey Marie Selecman

Theses and Dissertations (ETD)

Purpose: The objective of this study was to evaluate the osseointegration between plasma sprayed (PS) hydroxyapatite (HA) coated implants and electrophoresis deposited (EPD) nano hydroxyapatite coated implants in an animal model. The quantity of osseointegration was inferred by interfacial strength and percent tissue-contact length.Materials and Methods: Thirty-six cylindrical implants (18 PS and 18 EPD) were placed into dog mandibles. Nine implants from each group were evaluated with pull out testing and histological studies at 12 weeks after implantation. The remaining implants were occlusally loaded for 9 months and then evaluated by pull out testing and histological studies.Results: Twelve weeks after …