Open Access. Powered by Scholars. Published by Universities.®
Articles 1 - 2 of 2
Full-Text Articles in Medicine and Health Sciences
Does Time-Weighted Averaging For Wbgt And Metabolic Rate Work For Work-Recovery Cycles?, John W. Flach
Does Time-Weighted Averaging For Wbgt And Metabolic Rate Work For Work-Recovery Cycles?, John W. Flach
USF Tampa Graduate Theses and Dissertations
Heat stress affects thousands of works annually by causing heat-related illnesses. Wet bulb globe temperature (WBGT) is a widely accepted metric to assess the environmental contributions to heat stress. WBGT-based occupational exposure limits (OELs) include the ACGIH TLVs and the NIOSH RELs. The OEL threshold is adjusted downward with increasing metabolic rate. Further, there is an OEL for acclimatized and non-acclimatized workers. An often-recommended intervention found within a heat stress management program is work-recovery cycles to manage exposure. To prescribe work-recovery cycles, the common practice is to use time-weighted averaging (TWA) for the WBGT and the metabolic rate. The purpose …
Tudor Staphylococcal Nuclease Is A Docking Platform For Stress Granule Components And Is Essential For Snrk1 Activation In Arabidopsis, Emilio Gutierrez-Beltran, Pernilla H. Elander, Kerstin Dalman, Guy W. Dayhoff, Panagiotis N. Moschou, Vladimir N. Uversky, Jose L. Crespo, Peter V. Bozhkov
Tudor Staphylococcal Nuclease Is A Docking Platform For Stress Granule Components And Is Essential For Snrk1 Activation In Arabidopsis, Emilio Gutierrez-Beltran, Pernilla H. Elander, Kerstin Dalman, Guy W. Dayhoff, Panagiotis N. Moschou, Vladimir N. Uversky, Jose L. Crespo, Peter V. Bozhkov
Molecular Medicine Faculty Publications
Tudor staphylococcal nuclease (TSN; also known as Tudor-SN, p100, or SND1) is a multifunctional, evolutionarily conserved regulator of gene expression, exhibiting cytoprotective activity in animals and plants and oncogenic activity in mammals. During stress, TSN stably associates with stress granules (SGs), in a poorly understood process. Here, we show that in the model plant Arabidopsis thaliana, TSN is an intrinsically disordered protein (IDP) acting as a scaffold for a large pool of other IDPs, enriched for conserved stress granule components as well as novel or plant-specific SG-localized proteins. While approximately 30% of TSN interactors are recruited to stress granules …