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Full-Text Articles in Medicine and Health Sciences

Sex Differences In Cognitive Changes In De Novo Parkinson’S Disease, Ece Bayram, Sarah J. Banks, Guogen Shan, Nikki Kaplan, Jessica Z.K. Caldwell Dec 2019

Sex Differences In Cognitive Changes In De Novo Parkinson’S Disease, Ece Bayram, Sarah J. Banks, Guogen Shan, Nikki Kaplan, Jessica Z.K. Caldwell

Environmental & Occupational Health Faculty Publications

Objective: To evaluate the sex differences in cognitive course over 4 years in Parkinson’s disease (PD) patients with and without mild cognitive impairment (MCI) compared to controls. Methods: Four-year longitudinal cognitive scores of 257 cognitively intact PD, 167 PD-MCI, and 140 controls from the Parkinson’s Progression Markers Initiative were included. Longitudinal scores of men and women, and PD with and without MCI were compared. Results: Women had better verbal memory, men had better visuospatial function. There was no interaction between sex, diagnostic group, and/or time (4-year follow-up period). Conclusions: Sex differences in cognitive course in de novo PD are similar …


An Integrative Neurological Model For Basic Observable Human Behavior, Ryan M. Francis Jan 2016

An Integrative Neurological Model For Basic Observable Human Behavior, Ryan M. Francis

Calvert Undergraduate Research Awards

The scientific method uncovers information from the natural world in small increments. This spurs the design of models to explain how the pieces fit together and to identify future targets of research. This is especially the case in psychology, where visualizing concepts is an advantageous practice. One all too common criticism of cognitive and behavioral models in psychology is the lack of a biological basis. This paper aims to alleviate part of this issue by integrating currently understood biological and neurological mechanisms that drive psychological phenomena into a predictive and descriptive model for basic human behavior. To accomplish this task, …