Open Access. Powered by Scholars. Published by Universities.®

Medicine and Health Sciences Commons

Open Access. Powered by Scholars. Published by Universities.®

Articles 1 - 9 of 9

Full-Text Articles in Medicine and Health Sciences

The Utilization Of Crispr/Cas9 In Monogenic Disorders Authors, Shauna M. Mellor Aug 2022

The Utilization Of Crispr/Cas9 In Monogenic Disorders Authors, Shauna M. Mellor

Spectra Undergraduate Research Journal

This paper is a literature review of various scientific research papers, exploring the recent scientific advancement in the field of genetic engineering. The research presented is a foundational tool, building awareness on the implications of CRISPR/ Cas9 technology. CRISPR/ Cas9 was first discovered through the study of bacterial immune systems, fighting against viral infections. Manipulation of the Cas9 protein would eventually lead to target specific, gene-altering medicines for human organisms. CRISPR/ Cas 9 technology has begun to show promise as an effective treatment for certain monogenic disorders. Despite this, time is required before its efficacy as a proven genetic treatment …


Narrative Review Of Covid-19 Vaccine Hesitancy: Evidence In Late 2021, Ambree Papa Schoetker, Manoj Sharma Aug 2022

Narrative Review Of Covid-19 Vaccine Hesitancy: Evidence In Late 2021, Ambree Papa Schoetker, Manoj Sharma

Spectra Undergraduate Research Journal

The coronavirus disease, COVID-19, has changed daily life dramatically since early 2020. Although COVID-19 vaccines are available in the United States, many express distrust in this primary prevention measure and doubt both the seriousness of COVID-19 and its associated morbidity and mortality. Vaccine hesitancy, also described as the reluctance or refusal of vaccines despite availability, exists on a continuum and was a known public health threat prior to the coronavirus pandemic. This narrative review examines studies related to the determinants of COVID-19 vaccine hesitancy among adults in the United States. Also explored are the factors related to COVID-19 vaccine risk …


Implicit Bias Against Bipoc Patients In Clinical Settings: A Qualitative Review, Raisa Kabir, Sayeda Tazim Zaidi Feb 2022

Implicit Bias Against Bipoc Patients In Clinical Settings: A Qualitative Review, Raisa Kabir, Sayeda Tazim Zaidi

Spectra Undergraduate Research Journal

Black, Indigenous, and People of Color (BIPOC) from stigmatized and marginalized communities face implicit bias in medicine. Implicit biases are unconscious attitudes and internalized discrimination developed through repeated practices based on stereotypes from a foundation of systematic racism. In clinical settings, it impacts individuals’ healthcare experience and treatment outcomes. This study aimed to characterize and address implicit bias among healthcare providers toward BIPOC patients in clinical settings. A literature search in MEDLINE/PubMed, CINAHL, PsyArticles, PsycINFO from EBSCO databases was conducted to include all peer-reviewed studies (2012-2021) about implicit bias toward BIPOC. Most healthcare providers have some form of implicit bias-positive …


The “East Side” Of Las Vegas: A Latinx Historical Framework, Nathalie Martinez Aug 2021

The “East Side” Of Las Vegas: A Latinx Historical Framework, Nathalie Martinez

Spectra Undergraduate Research Journal

Spanish heritage speakers in the United States are a reflection of everchanging linguistic and sociolinguistic pressures that result in myriad varieties across generations. This paper provides a preliminary historical framework to fill this gap of linguistic knowledge in the Spanish-speaking community of Las Vegas, Nevada. The goals were two-fold: (1) highlight the largest Spanish-speaking communities in Las Vegas and (2) explore the significance of the East Side in the history of the Latinx population of Las Vegas. Through the analysis of oral histories and historical works, the investigation highlights the Mexican, Salvadoran, and Cuban populations of Las Vegas and their …


Qualitative Review Of Educational Interventions For Improving Physical Activity Behaviors In Older Asian Americans In The United States, Raisa Kabir, Manoj Sharma, Sayeda Tazim Zaidi, Chia-Liang Dai Aug 2021

Qualitative Review Of Educational Interventions For Improving Physical Activity Behaviors In Older Asian Americans In The United States, Raisa Kabir, Manoj Sharma, Sayeda Tazim Zaidi, Chia-Liang Dai

Spectra Undergraduate Research Journal

Physical activity (PA) provides numerous health benefits and minimizes chronic diseases and mental health issues, especially in older adults. The national survey data indicated that only 27.3% to 44.3% of older adults meet the recommended PA guidelines of 150 to 300 minutes/ week. There is limited data on PA behavior among older Asian American (AA) adults as very few to no local/national surveys have targeted these marginalized subgroups. This comprehensive review aims to identify existing PA intervention strategies and to update current knowledge on the effectiveness of these interventions to improve PA behavior among aging AA in the US. The …


The Future Of The Live Entertainment Tax In Southern Nevada, Katie M. Gilbertson Aug 2021

The Future Of The Live Entertainment Tax In Southern Nevada, Katie M. Gilbertson

Spectra Undergraduate Research Journal

The Live Entertainment Tax (LET) in Nevada generated nearly one billion dollars during the 2019-2020 fiscal year. LET revenue all goes to the State General Fund, even though 97 percent of LET revenue is generated in Clark County. Nevada is experiencing an economic crisis, particularly in the tourism industry. Solutions from various fields suggest the best way to boost the local economy is to reinvest revenue in its original county. One policy solution Nevada policymakers should consider is to carve out a percentage of revenue generated by the LET to return directly back to Clark County to revitalize tourism.


Diabetes Mellitus Affects Working Memory, Dylone C. Braganza, Emmanuel Flores, Lauren A. Crew, Ryan A. Wirt, Andrew A. Ortiz, Adam M. Mcneela, Jefferson W. Kinney, James M. Hyman Aug 2021

Diabetes Mellitus Affects Working Memory, Dylone C. Braganza, Emmanuel Flores, Lauren A. Crew, Ryan A. Wirt, Andrew A. Ortiz, Adam M. Mcneela, Jefferson W. Kinney, James M. Hyman

Spectra Undergraduate Research Journal

Alzheimer’s disease (AD) degrades the brain’s ability to remember, think, and carry out tasks. The exact cause is not known, but several risk factors have been identified, including diabetes mellitus (DM). DM causes elevated blood sugar levels due to reduced insulin production in the pancreas. The linkage between elevated glucose levels and the behavioral impairments are not fully understood, which was the focus of this study. Rats were trained to alternate directions in a maze to receive a reward on consecutive trials. After training, five rats were injected with streptozotocin (STZ), which induces hyperglycemia by injuring pancreatic beta cells. Three …


A Timeline Of Discovery And Current Research On Primary Open-Angle Glaucoma And Emergence Of Potentially Permanent Treatment Solutions, Yonosuke Dejesus, Guadalupe Moreno Ceballos Aug 2021

A Timeline Of Discovery And Current Research On Primary Open-Angle Glaucoma And Emergence Of Potentially Permanent Treatment Solutions, Yonosuke Dejesus, Guadalupe Moreno Ceballos

Spectra Undergraduate Research Journal

This research examines the timeline of the discovery and research of Primary Open-Angle Glaucoma (POAG). By reviewing the literature on genetic and molecular mechanisms, we aim to emphasize a long-term treatment solution (iSTENT) to mitigate intraocular pressure (IOP) related to POAG etiology and disease progression. POAG is a multifactorial, autosomal dominant, adult-onset eye disease wherein the optic nerve cells become damaged due to a buildup of excess aqueous humor, resulting in increased IOP. Consequently, POAG leads to progressive loss of peripheral vision and is the leading cause of blindness in the US. Due to the multifactorial nature of glaucoma’s inheritance …


Racial Profiling: Understanding The Practice Of Stop-And-Frisk In New York City, Lisa Ly Aug 2021

Racial Profiling: Understanding The Practice Of Stop-And-Frisk In New York City, Lisa Ly

Spectra Undergraduate Research Journal

Racial profiling has become a prominent issue in modern policing today. Instead of being based on individual suspicion, racial profiling embodies a belief that people of color are continuously singled out by the police for scrutiny and harassment. Policies and procedures make the Black community vulnerable to police discrimination and racial profiling. Floyd et al. v. City of New York et al. (2013) declared that the New York Police Department’s (NYPD) practice of stop-and-frisk was racially profiling Black civilians. This study sought (1) to determine if the NYPD post-Floyd is still engaging in racial profiling towards Black civilians; and (2) …