Open Access. Powered by Scholars. Published by Universities.®
- Discipline
-
- Medical Sciences (4)
- Communication Sciences and Disorders (3)
- Exercise Physiology (2)
- Life Sciences (2)
- Physiology (2)
-
- Sports Sciences (2)
- Cardiovascular Diseases (1)
- Diseases (1)
- Education (1)
- Health Services Research (1)
- Medical Biotechnology (1)
- Neurosciences (1)
- Nursing (1)
- Public Affairs (1)
- Public Affairs, Public Policy and Public Administration (1)
- Public Health (1)
- Social and Behavioral Sciences (1)
- Speech Pathology and Audiology (1)
Articles 1 - 12 of 12
Full-Text Articles in Medicine and Health Sciences
Effects Of Collaboration Between Speech-Language Pathologists And Third-Grade Teachers On Student Vocabulary Outcomes, Mary Mitchell
Effects Of Collaboration Between Speech-Language Pathologists And Third-Grade Teachers On Student Vocabulary Outcomes, Mary Mitchell
Electronic Theses and Dissertations
A persistent literacy crisis continues to be reflected in international (Organisation for Economic Co-operation and Development [OECD], 2013), national (National Center for Education Statistics [NCES], 2015), and local literacy outcome data. Educators, including speech-language pathologists (SLPs), are called upon to collaborate to support students who struggle with academic language/literacy. However, few studies have operationally defined collaboration and investigated the effects of collaboration on student achievement. As a result, there is insufficient guidance for educators about ways to design, implement, and assess the effectiveness of collaboration models, defined in terms of their effects on student outcomes. There were two main objectives …
The Actin-Severing Protein Cofilin Is Downstream Of Neuregulin Signaling, Is Regulated By The Tumor Suppressor Merlin, And Is Essential For Schwann Cell Myelination, Nicklaus Sparrow
Electronic Theses and Dissertations
Myelination is a complex process requiring coordination of directional motility and an increase in Schwann cell (SC) size to generate a multi-lamellar myelin sheath. Regulation of actin dynamics during myelination is poorly understood. However, it is known that myelin thickness is related to the abundance of neuregulin1-type III (NRG) expressed on the axon surface. NRG binding to ErbB2/3 receptors on the Schwann cell surface initiates signaling cascades necessary for myelination. We identify cofilin1, an actin depolymerizing and severing protein, as a downstream target of NRG-ErbB2/3 signaling in rat SC. A five minute exposure of SCs to NRG triggers phosphorylation of …
Factors Influencing Hypoglycemia Care Utilization And Outcomes Among Adult Diabetic Patients Admitted To Hospitals: A Predictive Model, Waleed Kattan
Factors Influencing Hypoglycemia Care Utilization And Outcomes Among Adult Diabetic Patients Admitted To Hospitals: A Predictive Model, Waleed Kattan
Electronic Theses and Dissertations
Diabetes Miletus (DM) is one of the major health problems in the United States. Despite all efforts made to combat this disease, its incidence and prevalence are steadily increasing. One of the common and serious side effects of treatment among people with diabetes is hypoglycemia (HG), where the level of blood glucose falls below the optimum level. Episodes of HG vary in their severity. Nevertheless, many require medical assistance and are usually associated with higher utilization of healthcare resources such as frequent emergency department visits and physician visits. Additionally, patients who experience HG frequently have poor outcomes such as higher …
Effects Of An Acute High-Volume Isokinetic Intervention On Circulating Levels Of Tnf-Α And Stnfr: Influence Of Age, Eliott Arroyo Delgado
Effects Of An Acute High-Volume Isokinetic Intervention On Circulating Levels Of Tnf-Α And Stnfr: Influence Of Age, Eliott Arroyo Delgado
Electronic Theses and Dissertations
The immune system has been implicated in recovery and muscle regeneration following exercise. In response to muscle damage, the immune system responds with an increase in circulating pro-inflammatory cytokines with the goal of recruiting leukocytes to the damaged area. Tumor Necrosis Factor-alpha (TNF-α), in particular, has been shown to be implicated in both muscle regeneration and muscle wasting. However, it remains unclear whether TNF-α is responsible for the age-related losses in muscle size and function. Also, due to the high clearance rate of TNF-α from circulation, analyzing the circulating levels of soluble TNF-α receptors 1 and 2 (STNFR1 and STNFR2) …
Consequences Of Altered Short-Chain Carbon Metabolism In Heart Failure, Julie Horton
Consequences Of Altered Short-Chain Carbon Metabolism In Heart Failure, Julie Horton
Electronic Theses and Dissertations
Cardiovascular disease is currently the foremost cause of death within the United States. Heart failure (HF) is a syndrome defined by the inability of the heart to adequately execute requisite pump function in order to deliver nutrients and oxygen to peripheral tissues, irrespective of etiology. One of the most common causes of HF is chronic pressure overload due to hypertension. Ischemic heart disease is also a common driver of HF, often in conjunction with hypertension. Pressure overload initially causes compensatory metabolic changes. Structural changes follow shortly thereafter typically resulting in left ventricular hypertrophy. Eventually, the heart loses the ability to …
Implication Of Alpha-Synuclein Transcriptional Regulation And Mutagenesis In The Pathogenesis Of Sporadic Parkinson's Disease, Sambuddha Basu
Implication Of Alpha-Synuclein Transcriptional Regulation And Mutagenesis In The Pathogenesis Of Sporadic Parkinson's Disease, Sambuddha Basu
Electronic Theses and Dissertations
Parkinson's disease (PD) is an age-related neurodegenerative disorder characterized by selective loss of dopaminergic neurons (DA neurons) from the substantia nigra (SN) of the mid-brain. PD is classically associated with cytoplasmic inclusion of aggregated proteins called Lewy bodies. alpha-synuclein (α-SYN) coded by the gene SNCA, is one of the major components of Lewy body and neurite along with several other proteins like ubiquitin, neurofilament to name a few. PD is broadly categorized into two groups based on their incidence of occurrence. First is the familial form that occurs due to known genetic aberrations like mutation, gene duplication/triplication in important PD …
Effects Of Symbol Type On Naming And Identification Of Graphic Symbols By Typically Developing Three, Four, Five And Six-Year Olds Children., Pamela Resnick
Effects Of Symbol Type On Naming And Identification Of Graphic Symbols By Typically Developing Three, Four, Five And Six-Year Olds Children., Pamela Resnick
Electronic Theses and Dissertations
Speech-language pathologists and educators face unique challenges in assessing the language skills of children with complex communication needs due to the wide array of impairments with which these individuals present. For example, most receptive language assessment tools require that children either point to or label line drawings to determine whether or not they comprehend the depicted concepts; task demands such as these preclude administering such assessment tools with children who are unable to physically point to or verbally label presented stimuli. In light of these challenges, the use of eye tracking technologies has become particularly appealing since this alternate response …
The Microbial Ecosystem Of Beer Spoilage And Souring: Competition And Cooperation In The Age Of Bioinformatics, Andrew Kettring
The Microbial Ecosystem Of Beer Spoilage And Souring: Competition And Cooperation In The Age Of Bioinformatics, Andrew Kettring
Electronic Theses and Dissertations
The brewing industry generates $350 billion in revenue in the US annually, representing 1.9% of the gross domestic product. Spoilage is a persistent problem throughout production and distribution that causes economic loss, and is therefore meticulously avoided. Contrarily, artisanal sour beers are necessarily produced by a diverse variety of these spoilage organisms metabolically interacting in symbiosis as a microbial ecosystem. We sought to gain insight into factors driving assembly of microbial communities by testing a long-debated Darwinian hypothesis. A collection of community members were screened in co-culture and novel bioinformatics tools were developed to predict observed interactions. A fundamental understanding …
Targeted Therapy Development For Neurofibromatosis Type 2, Marisa Fuse
Targeted Therapy Development For Neurofibromatosis Type 2, Marisa Fuse
Electronic Theses and Dissertations
Neurofibromatosis type 2 (NF2) is a debilitating disease characterized by the formation of bilateral vestibular schwannomas, which compress the vestibulocochlear nerve and cause deafness. Additional peripheral schwannomas, meningiomas and ependymomas may also form. NF2 is caused by mutations in the NF2 gene, resulting in the loss of function of the merlin tumor suppressor. Merlin functions in multiple signaling pathways and its absence in Schwann cells yields increased cell survival and proliferation, thereby causing schwannoma formation. First line treatment for NF2 is watchful waiting and surgical removal of tumors, potentially resulting in facial paralysis and deafness. To date, there are no …
The Influences Of Mindfulness And Neuromotor Exercise Mode On Balance In Healthy Older Adults, Maxine Hicks
The Influences Of Mindfulness And Neuromotor Exercise Mode On Balance In Healthy Older Adults, Maxine Hicks
Electronic Theses and Dissertations
This study investigated the roles of mindfulness and balance to optimize strategies for fall prevention in healthy older adults. The purpose of this study was to examine the association of mindfulness with respect to balance in healthy older adults who are experienced in meditative versus non-meditative modes of neuromotor exercise. This was a comparative descriptive study that used a convenience sample of N=86 older adults (20 male; mean age = 69.33 ± 7.24; range: 60 – 93 years). The sample included experienced participants of meditative (e.g., yoga, Tai chi) and non-meditative (e.g., partnered dance) neuromotor exercise recruited from community yoga, …
The Ability To Critically Evaluate Research Literature In Speech-Language Pathology, David Gregorio
The Ability To Critically Evaluate Research Literature In Speech-Language Pathology, David Gregorio
Electronic Theses and Dissertations
Research in Speech-Language Pathology provides the basis for understanding how and to what degree therapeutic techniques and interventions affect the health and quality of life of individuals with communication disorders. Across numerous fields of healthcare, research serves just as important a function and is used to guide the practices of professionals across the public health sector. Several disciplines, including chiropracty, nursing, and physical therapy, rely on the implementation of Evidence-Based Practice (EBP) to ensure that the process of rehabilitation and the techniques employed therein are carried out though the synthesis of best clinical judgment, empirical evidence, and patient values. The …
Effects Of An Acute High-Volume Isokinetic Intervention On Inflammatory And Strength Changes: Influence Of Age, Joseph Gordon
Effects Of An Acute High-Volume Isokinetic Intervention On Inflammatory And Strength Changes: Influence Of Age, Joseph Gordon
Electronic Theses and Dissertations
PURPOSE: The purpose of this study was to compare the effects of a high volume isokinetic intervention on lower body strength and inflammation, as well as markers of muscle damage in the subsequent 48 hours between younger and middle-aged men. METHODS: 19 healthy, recreationally trained men were randomly assigned to two groups, younger adults (YA: 21.8 ± 2.0 y; 90.7 ± 11.6 kg; 21.5 ± 4.1 % body fat), or middle-aged adults (MA: 47.0 ± 4.4 y; 96.0 ± 21.5; 24.8 ± 6.3 % body fat). Both groups reported to the human performance laboratory (HPL) on four separate occasions. On …