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Electronic Theses and Dissertations
Antibody; fab; phage display; rna; structured rnas; oncogenic rnas; trna; initiator trna; methionyl trna; trnaimet; trna fab; initiator trna fab
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Full-Text Articles in Medicine and Health Sciences
Preparation, Characterization, And Delivery Of Antibodies Binding To A Model Oncogenic Rna, Human Initiator Trna, Jennifer Archer
Preparation, Characterization, And Delivery Of Antibodies Binding To A Model Oncogenic Rna, Human Initiator Trna, Jennifer Archer
Electronic Theses and Dissertations
Non-coding RNAs (ncRNAs) account for a higher percent of the genome than coding mRNAs, and are implicated in human disease such as cancer, neurological, cardiac and many others. While the majority of ncRNAs involved in disease were originally attributed to a class of RNAs called micro RNAs (miRNAs) with a small size of only about 19 -24 base pairs, emerging research has now demonstrated a class of long non-coding RNAs (lncRNAs) that have a size of over 200 base pairs to be responsible for gene regulation and other functional roles and have also found to contribute to pathogenesis in humans. …