Medicine and Health Sciences Commons^™

Crítica Social Y Esperanza Para Las Próximas Generaciones: Representaciones De Seropositivos En Todo Sobre Mi Madre (1999) Y Positivo (2016), Grace Heiting

Honors Theses

This thesis criticizes the progression of the HIV/AIDS pandemic from post-Franco Spain to contemporary Venezuela through the analysis of a domestic film from each country. From Spain, the comedy-drama film Todo sobre mi madre (1999) by Pedro Almodóvar is a reflection of an earlier stage of the epidemic, when the country was challenged to recreate its political and social identities. Almodóvar’s film highlights the struggles of the LGBTQ community to transgress stereotypes (not limited to HIV) and find hope in future generations to solve the lingering social inequalities. From Venezuela, the short film Positivo (2016) from De Tovar Films is …

Cortisol Receptor Sensitivity As A Risk Factor For Depression, Michela Michielli

Honors Theses

In 2020, the World Health Organization reported over 264 million people across the world were suffering from depression. Studies have demonstrated that one source of depression is a hormonal imbalance involved in the stress response. Cortisol is a stress hormone regulated by the Hypothalamic-Anterior-Pituitary (HPA) Axis. Its effects on the stress response and other metabolic activities in the body are exerted through the glucocorticoid and mineralocorticoid receptors (GR and MR respectively).

Our research has examined mutations known as single-nucleotide-polymorphisms (SNPs) relating to cortisol-receptor sensitivity and the behavior of cortisol in the body to investigate the link between cortisol activity and …

Diisopinocampheylborane Trifluoromethanesulfonate-Mediated Aldol Reactions Using An Aldehyde And An Amide, Camille Parker

Honors Theses

Aldol reactions are one of the most powerful reactions in organic chemistry because of the formation of new carbon-carbon bonds. A downside of aldol reactions is that they generate a mix of stereoisomers, therefore a lot of work has gone into developing methods that selectively favor a certain stereoisomer. We report an enatio and diastereoselective diisopinocampheylborane trifluoromethanesulfonate ((Ipc)₂BOTf) mediated aldol reaction with an amide and an aldehyde. Traditionally, (Ipc)₂BOTf-mediated reactions were not applied to amides, except with the use of strong bases. Here we developed a (Ipc)₂BOTf aldol reaction of amides using mild bases …

Ocd: The Effects Of Doubt On Memory Confidence, Amber Raisner

Honors Theses

Obsessive compulsive disorder (OCD) is an anxiety disorder that affects 1% of

the United States population, and is categorized by both obsessive thoughts and compulsive behaviors. The most prevalent compulsive behavior is checking, which is an attempt to mitigate anxiety about a situation the person believes will be harmful if not addressed. Previous studies suggest a negative correlation between checking and metamemory (memory confidence, vividness and detail); however, there has been limited research on the effects of doubt, one of the main causes of checking behaviors, on metamemory. The current study used an online stove-checking task, first used by van …

The Impact Of Single Nucleotide Polymorphisms On Cortisol Receptor Activity In Populations With Obesity, Cassidy Michalicka

Honors Theses

Cortisol is a crucial part of the endocrine system; it has the capacity to affect nearly every organ and tissue in the human body. When functioning correctly, cortisol is known to regulate the body’s stress response, control metabolism, suppress inflammation, regulate blood pressure, regulate blood sugar, regulate our body’s circadian rhythm, and much more. When the concentration of cortisol in the blood is elevated for an excessive period, the body responds with symptoms such as hyperglycemia, hypertension, weight gain, and moon face. Commonly this is known as Cushing’s Syndrome (CS), and interestingly, we have seen a phenotypic resemblance when contrasted …

Pixe Analysis Of Heavy Metals In Soil Along The East River, Mia Villeneuve

Honors Theses

We collected samples of soil from along the East River in Queens, New York, near the Hell Gate Bridge, on the Astoria Park side of the bridge in 2019 and on the Randall’s Island Park side in 2021. We performed proton-induced X-ray emission (PIXE) analysis on the samples and found that soil closer to the Hell Gate Bridge contained higher concentrations of heavy metals, specifically lead and zinc. Many of the soil samples contained lead concentrations greater than the EPA standard of 400 ppm. We also performed PIXE analysis on a sample of the paint used on the bridge and …