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Full-Text Articles in Medicine and Health Sciences

The Mechanisms Of Weight Gain In Sleep-Deprived Individuals, Chaya Rosen Jan 2015

The Mechanisms Of Weight Gain In Sleep-Deprived Individuals, Chaya Rosen

The Science Journal of the Lander College of Arts and Sciences

The obese population in America has grown during the last century. During these years as well, American’s have been sleeping less. Cross sectional studies show that there is a correlation of the two factors, and indeed find a greater number of overweight individuals amongst the sleep-deprived population. Though they are unclear, studies attempt to establish possible mechanisms through which weight gain occurs. Results of studies show that sleep deprivation may influence leptin and ghrelin levels, which can cause hunger, and excessive caloric intake. Sleep-deprived individuals also have an increased opportunity to eat during the wakeful nighttime hours. In the sleep-restricted …


How Does The Brain Implement Adaptive Decision Making To Eat?, Valérie Compan, B. Timothy Walsh, Walter Kaye, Allan Geliebter Jan 2015

How Does The Brain Implement Adaptive Decision Making To Eat?, Valérie Compan, B. Timothy Walsh, Walter Kaye, Allan Geliebter

Lander College of Arts and Sciences Publications and Research

Adaptive decision making to eat is crucial for survival, but in anorexia nervosa, the brain persistently supports reduced food intake despite a growing need for energy. How the brain persists in reducing food intake, sometimes even to the point of death and despite the evolution of multiple mechanisms to ensure survival by governing adaptive eating behaviors, remains mysterious. Neural substrates belong to the reward-habit system, which could differ among the eating disorders. The present review provides an overview of neural circuitry of restrictive food choice, binge eating, and the contribution of specific serotonin receptors. One possibility is that restrictive food …


Regulation Of Ghrelin: A Possible Treatment Option For Obesity And Diabetes, Sarah Picciotto Jan 2015

Regulation Of Ghrelin: A Possible Treatment Option For Obesity And Diabetes, Sarah Picciotto

The Science Journal of the Lander College of Arts and Sciences

Obesity is a mounting problem in America today. One major concern about obesity is that it is a risk factor for type 2 diabetes, a disease that impairs insulin sensitivity and secretion. This interferes with blood glucose levels and can cause hyperglycemia, which is when there is too much circulating glucose in the blood. Ghrelin, an amino acid peptide responsible for appetite stimulation and energy balance, plays a direct role in insulin secretion and glucose metabolism. In many experiments, elevated ghrelin levels are associated with decreased insulin secretion from pancreatic islet cells. Although ghrelin concentration is decreased in obese individuals …


The Effect Of Bmi On Oxygen Saturation At Rest And During Mild Walking, Jerrold S. Petrofsky, Michael S. Laymon, Iman Akef Khowailed, Stacy Fisher, Andrew Mills Jan 2015

The Effect Of Bmi On Oxygen Saturation At Rest And During Mild Walking, Jerrold S. Petrofsky, Michael S. Laymon, Iman Akef Khowailed, Stacy Fisher, Andrew Mills

College of Health & Human Services (TUN) Publications and Research

Eighty one subjects were examined for the relationship between BMI, body fat, arterial oxygen saturation and arterial PO2 with the subjects at rest and after 5 minutes of walking on a treadmill ergometer at 3 mph at a 3% grade. They had BMIs between 19 and 50. All subjects were free of cardiovascular disease and had normal blood pressure making it safe for them to participate in mild exercise. They were all able to walk for at least 10 minutes without cardiovascular complications and were not taking any medications that altered the autonomic nervous system. The age was between 22 …