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Full-Text Articles in Medicine and Health Sciences
Comparative Effectiveness Of Total Population Versus Disease-Specific Neural Network Models In Predicting Medical Costs, Albert G. Crawford, Joseph P. Fuhr Jr., Janice Clarke, Brandon Hubbs
Comparative Effectiveness Of Total Population Versus Disease-Specific Neural Network Models In Predicting Medical Costs, Albert G. Crawford, Joseph P. Fuhr Jr., Janice Clarke, Brandon Hubbs
College of Population Health Faculty Papers
The objective of this research was to compare the accuracy of two types of neural networks in identifying individuals at risk for high medical costs for three chronic conditions. Two neural network models—a population model and three disease-specific models—were compared regarding effectiveness predicting high costs. Subjects included 33,908 health plan members with diabetes, 19,264 with asthma, and 2,605 with cardiac conditions. For model development/testing, only members with 24 months of continuous enrollment were included. Models were developed to predict probability of high costs in 2000 (top 15% of distribution) based on 1999 claims factors. After validation, models were applied to …
Use Of Chromium Picolinate And Biotin In The Management Of Type 2 Diabetes: An Economic Analysis, Joseph P. Fuhr Jr., Hope He, Neil Goldfarb, David B. Nash
Use Of Chromium Picolinate And Biotin In The Management Of Type 2 Diabetes: An Economic Analysis, Joseph P. Fuhr Jr., Hope He, Neil Goldfarb, David B. Nash
College of Population Health Faculty Papers
This paper addresses the potential economic benefits of chromium picolinate plus biotin (Diachrome ®) use in people with Type 2 diabetes (T2DM). The economic model was developed to estimate the impact on health care systems’ costs by improved HbA1C levels with chromium picolinate plus biotin (Diachrome). Lifetimes cost savings were estimated by adjusting a benchmark from the literature, using a price index to adjust for inflation. The cost of diabetes is highly dependent on the HbA1C level with higher initial levels and higher annual increments increasing the cost. Improvement in glycemic control has proven to be cost-effective in delaying the …
Multiple Metabolic Hits Converge On Cd36 As Novel Mediator Of Tubular Epithelial Apoptosis In Diabetic Nephropathy, Katalin Susztack, Emilio Ciccone, Peter Mccue, Kumar Sharma, Erwin Böttinger
Multiple Metabolic Hits Converge On Cd36 As Novel Mediator Of Tubular Epithelial Apoptosis In Diabetic Nephropathy, Katalin Susztack, Emilio Ciccone, Peter Mccue, Kumar Sharma, Erwin Böttinger
Department of Medicine Faculty Papers
Diabetic nephropathy (DNP) is a common complication of type 1 and type 2 diabetes mellitus and the most common cause of kidney failure. While DNP manifests with albuminuria and diabetic glomerulopathy, its progression correlates best with tubular epithelial degeneration (TED) and interstitial fibrosis. However, mechanisms leading to TED in DNP remain poorly understood.