Medicine and Health Sciences Commons^™

The Effects Of The Tootling Intervention Using Daily Reinforcement, Melissa Bryanne Mchugh

Master's Theses

The current study was designed to replicate and extend the literature on the effectiveness of a classroom intervention known as Tootling (Skinner, Skinner, & Cashwell, 1998) in decreasing disruptive classroom behavior as well as increasing academically engaged classroom behavior. Tootling is a strategy that encourages and prompts students to report instances of their peers’ positive behaviors. Thus far, only three studies have utilized direct observation data for disruptive behavior during Tootling (Cihak, Kirk, & Boon, 2009; Lambert, 2012, 2014). To extend the research on Tootling, direct observation data of disruptive and academically engaged behaviors were collected on both entire classes …

Self-Assembled Gold Nanoplexes For Cancer-Targeted Sirna Delivery, Yongliang Shi

Master's Theses

Through layer-by-layer method, the authors have constructed three Au nanoplexes: AuPEI/RNA/PEI, AuPEI/RNA/PEI-mPEG, and AuPEI/NA/PEI-PEG-FA. All the nanoplexes are characterized by UV-vis spectrometry, DLS, and zeta potential. The surface density of the first layer PEI and second layer RNA were also determined. Moreover, the Au nanoplexes can protect siRNA from RNase degradation and are stable in cell culture medium.

siGLuc-ppp, ssRNA₈₀, and siF17 were delivered by the assembled Au nanoplexes, and the results were analyzed by GLuc assay, TB assay, and Luciferase assay. In terms of RNA delivery, the Au nanoplexes AuPEI/RNA/PEI exhibited excellent gene silencing efficiency (or causing …

Evaluation Of A Theory-Based Farm To School Program, Rebecca Kent Bishop

Master's Theses

Fruit and vegetable (FV) intakes in MS children remain lower than recommended. Theory-based, multi-component nutrition education interventions like Farm to School (F2S) target FV consumption and utilize such interventions to improve children’s dietary behaviors by incorporating nutrition and agriculture education. The current study was designed with Theory of Planned Behavior (TPB) as its framework. An intervention was implemented to enhance beliefs, norms, and self-efficacy regarding FV, thus potentially increasing the intention to consume more FV. The research objectives of this study are to describe changes over the course of the intervention in (1) nutrition knowledge; (2) norms, beliefs, and self-efficacy …

Propagation Of Oligomeric Α-Synuclein And Amyloid-Β: Implications For Parkinson's And Alzheimer's Diseases, Matthew Stephen Planchard

Master's Theses

The aggregation of amyloidogenic proteins is a critical event in the pathology of a variety of neurodegenerative diseases, including Alzheimer’s disease (AD) and Parkinson’s disease (PD). The proteins α-synuclein (αS) and amyloid-β (Aβ) are involved in the formation of amyloid lesions observed in PD and AD, respectively. Both PD and AD exhibit a significant amount of co-pathology in clinical settings, and the αS and Aβ proteins have been shown to interact in vitro. Recent experimental consensus has shown oligomeric species to be significant, if not primary, sources of toxicity in these diseases. …