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Full-Text Articles in Medicine and Health Sciences

Assessment Of Tumor-Induced Pain And C-Reactive Protein Levels In Dogs With Caninetransmissible Venereal Tumors, Waqas Ahmad, Muti-Ur- Rehman, Aftab Ahmad Anjum, Gulbeena Saleem, Ubaid Ur Rehman Zia, Muhammad Azeem, Fahad Akram Jan 2018

Assessment Of Tumor-Induced Pain And C-Reactive Protein Levels In Dogs With Caninetransmissible Venereal Tumors, Waqas Ahmad, Muti-Ur- Rehman, Aftab Ahmad Anjum, Gulbeena Saleem, Ubaid Ur Rehman Zia, Muhammad Azeem, Fahad Akram

Turkish Journal of Veterinary & Animal Sciences

The aim of this study was to determine the impact of tumor volume on generalized behavior, pain perception, and serum C-reactive protein (CRP) in dogs with canine transmissible venereal tumors (CTVTs). Pain scoring was performed using the Glasgow Composite Measure Pain Scale Short-Form. Cytomorphology of the tumors was studied through fine-needle aspiration and histopathology. Molecular identification of CTVTs was carried out using PCR assays based on LINE-1/c-myc. Hematological profiles including complete blood count and CRP were analyzed using an automatic hematology analyzer and immunoturbidimetric assays, respectively. Chi-square and regression analysis statistics were used for data analysis. Results of the study …


Increased Micronucleus Count Predicts Malignant Behavior In Pleural Effusion Fluid, Tuba Di̇lay Kökenek Ünal, İpek Çoban Jan 2018

Increased Micronucleus Count Predicts Malignant Behavior In Pleural Effusion Fluid, Tuba Di̇lay Kökenek Ünal, İpek Çoban

Turkish Journal of Medical Sciences

Background/aim: Micronucleus (MN) frequency is used as a biomarker of chromosomal damage, genome instability, and cancer risk. e aim of this study was to evaluate the diagnostic usefulness of MN frequency to di erentiate between malignant and benign pleural e usion samples. Materials and methods: Retrospectively, 78 pleural uid cytology samples (including 20 cases of benign reactive mesothelial cells, 22 cases of suspicious cytology, and 36 cases of malignant cytology) were examined. e number of micronucleated cells in 1000 well- preserved cells was counted. Statistical tests were performed to compare the study groups. Recover operating characteristics (ROC) curve analysis was …


Hpv Types And E6/E7 Mrna Expression In Cervical Samples From Turkish Women With Abnormal Cytology In Ankara, Turkey, İpek Tüney, Ayli̇n Altay, Koray Ergünay, Sevgen Çeli̇k Önder, Alp Usubütün, Mehmet Coşkun Salman, Gülendam Bozdayi, Erdem Karabulut, Osman Seli̇m Badur, Kunter Yüce, Ahmet Pinar Jan 2017

Hpv Types And E6/E7 Mrna Expression In Cervical Samples From Turkish Women With Abnormal Cytology In Ankara, Turkey, İpek Tüney, Ayli̇n Altay, Koray Ergünay, Sevgen Çeli̇k Önder, Alp Usubütün, Mehmet Coşkun Salman, Gülendam Bozdayi, Erdem Karabulut, Osman Seli̇m Badur, Kunter Yüce, Ahmet Pinar

Turkish Journal of Medical Sciences

Background/aim: Human papillomaviruses have been established as a risk factor for invasive carcinoma of the uterine cervix. HPV E6/E7 oncogene expression has recently emerged as a promising biomarker to determine the risk for progression to high-grade cervical lesions. The aim of this study was to evaluate HPV mRNA and DNA detection in samples with abnormal cytology. Materials and methods: Cervical specimens were obtained at the Department of Obstetrics and Gynecology via cervical brushes during January-October 2011. Liquid-based cytology slides were evaluated according to the 2001 Bethesda System. Cytology specimens from a total of 81 women with abnormal cytology were included. …


Endometrial Cytology As A Diagnostic Tool For Subclinical Endometritis In Beef Heifers, Carlos Moscuzza, Guadalupe Alvarez, Betiana Gutierrez, Marcelo Zurita, Marcelo Tropeano, Roberto Perna Jan 2015

Endometrial Cytology As A Diagnostic Tool For Subclinical Endometritis In Beef Heifers, Carlos Moscuzza, Guadalupe Alvarez, Betiana Gutierrez, Marcelo Zurita, Marcelo Tropeano, Roberto Perna

Turkish Journal of Veterinary & Animal Sciences

The obstetric assistance of dystocia in field conditions promotes greater bacterial contamination of the uterus, causing subclinical endometritis. The aim of this study was to determine the occurrence of subclinical endometritis in beef heifers receiving professional calving assistance, and to evaluate endometrial cytology as a diagnostic technique compared to uterine biopsy. A group of 829 Angus heifers were assisted at calving. Dystocia was classified based on difficulty at assistance, which was estimated as complex or simple. At the end of the calving season, 93 dystocic heifers were reported (10.7%). The percentage of simple resolution and complex resolution was 88.2% and …


The Risk Of Tumor Cell Dissemination In Mediastinoscopy: A Cytological Study, Yasemi̇n Bi̇lgi̇n Büyükkarabacak, Ayşen Taslak Şengül, Bi̇lge Can Meydan, Burçi̇n Çeli̇k, Mehmet Gökhan Pi̇rzi̇renli̇, Selçuk Gürz, Zeynep Peli̇n Sürücü, Ahmet Başoğlu Jan 2015

The Risk Of Tumor Cell Dissemination In Mediastinoscopy: A Cytological Study, Yasemi̇n Bi̇lgi̇n Büyükkarabacak, Ayşen Taslak Şengül, Bi̇lge Can Meydan, Burçi̇n Çeli̇k, Mehmet Gökhan Pi̇rzi̇renli̇, Selçuk Gürz, Zeynep Peli̇n Sürücü, Ahmet Başoğlu

Turkish Journal of Medical Sciences

Background/aim: Mediastinoscopy is an invasive procedure that is used in the diagnosis of mediastinal diseases and in staging lung cancer. Tumor cell seeding during mediastinoscopy along the mediastinum and the incision line is a very rare complication. This study aimed to test the safety of mediastinoscopy in terms of tumor seeding by cytological evaluation of mediastinal lavage samples taken before and after biopsy. Materials and methods: The patients who underwent mediastinoscopy in our hospital between 2011 and 2014 were studied prospectively. Seventy-three patients with a diagnosis of lung or mediastinal malignancy were included in the study. All patients underwent classical …


Human Papillomavirus Prevalence And Type In Liquid-Based Cervical Samples From Turkish Women In A Selected Risk Group, Işin Akyar, Özlem Aydin, Mustafa Cengi̇z Yakicier, Zühtü Tanil Kocagöz, Ümi̇t İnce, İbrahi̇m Ünsal Jan 2013

Human Papillomavirus Prevalence And Type In Liquid-Based Cervical Samples From Turkish Women In A Selected Risk Group, Işin Akyar, Özlem Aydin, Mustafa Cengi̇z Yakicier, Zühtü Tanil Kocagöz, Ümi̇t İnce, İbrahi̇m Ünsal

Turkish Journal of Medical Sciences

To detect the prevalence and type distribution of human papillomavirus (HPV) in different cytological diagnostic categories. Materials and methods: Between 2007 and 2010, a total of 1014 liquid-based thin preparations of cervical smears were selected and classified according to cytology results. HPV DNA polymerase chain reaction (PCR) was also performed using these samples. HPV DNA-positive samples were genotyped by DNA sequencing. Results: Of those enrolled in the study, 45.3% were negative cytologically, 36.4% had atypical squamous cells of undetermined significance, 0.3% had atypical squamous cells preventing the exclusion of a high-grade squamous intraepithelial lesion, 16.8% showed a low-grade squamous intraepithelial …


Diagnostic Value Of Ki-67li In Hepatocellular Carcinoma Ki-67 Antigen Expression In Hepatocellular Carcinoma, Metastatic Adenocarcinoma And Normal Hepatocytes, Işin Soyuer, Cemi̇l Eki̇nci̇, Muhsi̇n Kaya, Yasemi̇n Genç, Kadi̇r Bahar Jan 2003

Diagnostic Value Of Ki-67li In Hepatocellular Carcinoma Ki-67 Antigen Expression In Hepatocellular Carcinoma, Metastatic Adenocarcinoma And Normal Hepatocytes, Işin Soyuer, Cemi̇l Eki̇nci̇, Muhsi̇n Kaya, Yasemi̇n Genç, Kadi̇r Bahar

Turkish Journal of Medical Sciences

One hundred liver fine-needle aspiration cytology (FNAC) specimens obtained from 42 patients with hepatocellular carcinomas (HCC), 38 patients with metastatic adenocarcinomas (MAC) and 20 patients with non-malignant liver disease (control group) were studied. Liver specimens were stained with an immunoperoxidase method using a monoclonal antibody to Ki-67 (MIB1). Ki-67 antigen was visualised in cold acetone, and a fresh liver needle aspiration cytology specimen using antibodies was used to identify proliferating hepatocytes. In this study it was examined that; if there is a difference between the groups in terms of Ki-67 positivity and degree of differentiation of tumor and the relationship …