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Full-Text Articles in Medicine and Health Sciences
Randomized Phase Iii Trial Of Piroxicam In Combination With Mitoxantrone Or Carboplatin For First-Line Treatment Of Urogenital Tract Transitional Cell Carcinoma In Dogs., Sara D. Allstadt, C O. Rodriquez, B Boostrom, R B. Rebhun, K A. Skorupski
Randomized Phase Iii Trial Of Piroxicam In Combination With Mitoxantrone Or Carboplatin For First-Line Treatment Of Urogenital Tract Transitional Cell Carcinoma In Dogs., Sara D. Allstadt, C O. Rodriquez, B Boostrom, R B. Rebhun, K A. Skorupski
Sara Allstadt, DVM, Diplomate ACVIM (Oncology)
BACKGROUND: Reported response rates of transitional cell carcinoma (TCC) in dogs to piroxicam in combination with either mitoxantrone or carboplatin are similar; however, it is unknown whether either drug might provide superior duration of response. HYPOTHESIS/OBJECTIVES: To determine if the progression-free interval (PFI) of dogs with TCC treated with mitoxantrone and piroxicam was different than that of dogs receiving carboplatin and piroxicam. The hypothesis was that the efficacy of mitoxantrone is no different from carboplatin. ANIMALS: Fifty dogs with TCC without azotemia. METHODS: Prospective open-label phase III randomized study. Either mitoxantrone or carboplatin was administered every 3 weeks concurrently with …
Collagen-Calcium Alginate Film Dressing With Therapeutic Ultrasound To Treat Open Wound In Rats, Khaled M. A Hussin, Asma Saleh Elmabrok
Collagen-Calcium Alginate Film Dressing With Therapeutic Ultrasound To Treat Open Wound In Rats, Khaled M. A Hussin, Asma Saleh Elmabrok
Asma Saleh Elmabrok
Abstract: About 24 healthy female Sprague-Dawley rats weighing between 300-350 g were used in this study over a 20 day period. They were allocated randomly into 4 groups of 6 animals each. After the creation of 2x2 em open wound, group 1 was control treated with Gentamycin ointment. Groups 2-4 were treated with Therapeutic ultrasound massage, collagen-calcium alginate film and collagen-calcium alginate film with therapeutic ultrasound. On application, the collagen-calcium alginate film with therapeutic ultrasound was well accepted by the animals without any adverse reaction. Mean percentage of wound contraction were significantly better in group 4 (p<0.05). Faster epithelialization was also seen in the collagen-calcium alginate film with therapeutic ultrasound treated group as compared to the other groups. Collagen is a biocompatible protein that does not interfere with the body's normal immunologic response and can be used in non-healing chronic wounds which require a trigger to stimulate the normal healing process. In extensive wounds when there is lack of autologous tissue, biomaterials like collagen-calcium alginate may be beneficial and can be used.
Impact Of A Logistics Management Program On Admitted Patient Boarders Within An Emergency Department, Mary Ann Healy-Rodriguez, Rula Wilson, Chris Freer, Laura Pontiggia, Stephen Metraux, Lyndsey Lord
Impact Of A Logistics Management Program On Admitted Patient Boarders Within An Emergency Department, Mary Ann Healy-Rodriguez, Rula Wilson, Chris Freer, Laura Pontiggia, Stephen Metraux, Lyndsey Lord
Stephen Metraux
Introduction: ED crowding is a public health issue, and hospitals across the country must pursue aggressive strategies to improve patient flow to help solve this growing problem. The logistics management program (LMP) is an expansion of the bed management process to include a systematic approach to patient flow management throughout the facility and a clinical liaison or field agent to drive throughput at all points of care. The purpose of this study was to examine the effects of an LMP on ED length of stay (ED evaluation times and ED placement times), as well as inpatient length of stay (IPLOS). …
Providing An Information Prescription Veterinary Medical Clinics: A Pilot Study, Lori Kogan, Regina Schoenfeld-Tacher, Ann R. Viera, Lauren Gould, Peter Hellyer
Providing An Information Prescription Veterinary Medical Clinics: A Pilot Study, Lori Kogan, Regina Schoenfeld-Tacher, Ann R. Viera, Lauren Gould, Peter Hellyer
Ann R Viera MLIS
No abstract provided.
Nice But Needy: English Guidance On Managing Alcohol Dependence Is Not Backed Up By Government Alcohol Policy, Laura Williamson
Nice But Needy: English Guidance On Managing Alcohol Dependence Is Not Backed Up By Government Alcohol Policy, Laura Williamson
Dr Laura Williamson
No abstract provided.
Adding Substance To Strategy, Laura Williamson, Susan Kerr
Adding Substance To Strategy, Laura Williamson, Susan Kerr
Dr Laura Williamson
No abstract provided.
Public Policy On Alcohol In The United Kingdom: Towards A Safety Net For The Alcohol-Dependent, Laura Williamson
Public Policy On Alcohol In The United Kingdom: Towards A Safety Net For The Alcohol-Dependent, Laura Williamson
Dr Laura Williamson
Public policy on alcohol in the United Kingdom fails to support, and may even undermine, the wellbeing of those with the worst alcohol misuse problems, the alcohol-dependent. This is partly because it evades the thorny issue of impaired control that characterises dependence. In addition, until recently, all United Kingdom alcohol policy focused on improving individualised treatment for the dependent, rather than attending to the wider social and environmental factors that influence the condition. The efforts of policy to normalise "sensible" drinking, while stigmatising drunkenness, also risk exacerbating the social vulnerability of the alcohol-dependent. The article examines these issues and concludes …
Scotland: Leading The Way For Alcohol Policy In The United Kingdom?, Laura Williamson
Scotland: Leading The Way For Alcohol Policy In The United Kingdom?, Laura Williamson
Dr Laura Williamson
In March 2009, the Scottish Government published a new strategy for addressing the harms associated with alcohol misuse entitled Changing Scotland’s Relationship with Alcohol: A Framework for Action. The document is important for health ethics because it signals a philosophical shift in the way countries in the United Kingdom address alcohol related harms.
Empirical Assessments Of Clinical Ethics Services: Implications For Clinical Ethics Committees’, Laura Williamson
Empirical Assessments Of Clinical Ethics Services: Implications For Clinical Ethics Committees’, Laura Williamson
Dr Laura Williamson
The need to evaluate the performance of clinical ethics services is widely acknowledged although work in this area is more developed in the United States. In the USA many studies that assess clinical ethics services have utilized empirical methods and assessment criteria. The value of these approaches is thought to rest on their ability to measure the value of services in a demonstrable fashion. However, empirical measures tend to lack ethical content, making their contribution to developments in ethical governance unclear. The steady increase of clinical ethics committees in the UK must be accompanied by efforts to evaluate their performance. …
The Regulation Of Xenotransplantation In The Uk After Ukxira: Legal And Ethical Issues’, Laura Williamson, Marie Fox, Sheila Mclean
The Regulation Of Xenotransplantation In The Uk After Ukxira: Legal And Ethical Issues’, Laura Williamson, Marie Fox, Sheila Mclean
Dr Laura Williamson
Xenotransplantation - the transfer of living tissue between species - has long been heralded as a potential solution to the severe organ shortage crisis experienced by the United Kingdom and other `developed' nations. However, the significant risks which accompany this biotechnology led the United Kingdom to adopt a cautious approach to its regulation, with the establishment of a non-departmental public body - UKXIRA - to oversee the development of this technology on a national basis. In December 2006 UKXIRA was quietly disbanded and replaced with revised guidance, which entrusts the regulation of xenotransplantation largely to research ethics committees. In this …
Clinical Ethics Committees In The United Kingdom – Towards Evaluatio, Laura Williamson
Clinical Ethics Committees In The United Kingdom – Towards Evaluatio, Laura Williamson
Dr Laura Williamson
In the United Kingdom there is a growing conviction that CECs have an important role to play in helping health care professionals address ethical dilemmas. For example, the Royal College of Physicians, the Nuffield Trust and the unofficial Clinical Ethics Network, which has received financial support from the Department of Health, commend the use of CECs in the UK. The growth of such committees has been influenced by the legal and policy support they have received in the United States. However, there is increasing concern about both the benefits and the quality of work produced by CECs. In addition, despite …