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Characterization Of Bovine-Derived Porous Hydroxyapatite Scaffold And Its Potential To Support Osteogenic Differentiation Of Human Bone Marrow Derived Mesenchymal Stem Cells., Krishnamurithy G, Murali Mr, Hamdi M, Abbas Aa, Raghavendran Hb, Kamarul T
Characterization Of Bovine-Derived Porous Hydroxyapatite Scaffold And Its Potential To Support Osteogenic Differentiation Of Human Bone Marrow Derived Mesenchymal Stem Cells., Krishnamurithy G, Murali Mr, Hamdi M, Abbas Aa, Raghavendran Hb, Kamarul T
Murali Malliga Raman
Porous three-dimensional hydroxyapatite (HA) scaffolds were prepared using bovine cortical bone derived HA (BDHA). Analyses of the morphology, chemical composition, and phase purity of the scaffold were performed using scanning electron microscopy (SEM), micro-computer tomography (micro-CT), Fourier transform infrared spectroscopy (FTIR), energy dispersive X-ray spectroscopy (EDX), and X-ray diffraction (XRD). SEM images revealed the rough and porous surface of the scaffold, while micro-CT showed the average porous volume of 76.7±0.6% and pore size of 0.04–0.25 mm. Single phase corresponding to standard HA was observed using XRD, and FTIR confirmed the presence of functional groups similar to HA. The EDX analysis …