Medicine and Health Sciences Commons^™

Mindspace: A Multi-Media Art Exhibition On C-Ptsd Awareness, Emma Wallace

Student Research Symposium

"Mindspace" is an autobiographical art exhibition aimed at raising awareness about Complex Post-Traumatic Stress Disorder (C-PTSD) through a multi-sensory experience. The exhibition combines sculpture, lights, sound, and video projection to immerse viewers in the intricate emotional landscape of C-PTSD. Through a series of sculptural installations and carefully curated lighting and audio, visitors are invited to explore the internal world of an artist affected by C-PTSD and learn how it differs from PTSD and other types of mental health issues.

“Mindspace" incorporates specially composed soundscapes that offer an intimate look into the artist’s thoughts and memories, which range from spoken word …

Impact Of Intersecting Vulnerabilities On Functional Outcome And Health-Related Quality Of Life After Traumatic Brain Injury: A Prospective Cohort Study, Rekesh Subedi, Tatiana Hoyos-Gomez, Luis Tinoco-Garcia, John Cervantes Cervantes

Student Research Symposium

Traumatic Brain Injury (TBI) is a critical public health issue that disproportionately affects select vulnerable populations, including race/ethnic minorities, low-income individuals, and those without health insurance. Despite high incidences of TBI and its considerable impact on morbidity and mortality, research is limited in addressing how the intersectionality of vulnerabilities contributes to outcomes post-TBI. This literature review aims to synthesize existing knowledge regarding Social determinants of health (SDH) on TBI outcomes, focusing on functional recovery and health-related quality of life (HRQOL). This study will use a prospective cohort research design where TBI patients at Oregon Health and Science University (OHSU) will …

Interpersonal Experiential Learning And Cancer Research Training Designed To Enhance The Motivation Of Participating Interns Utilizing Self-Determination Theory: A Longitudinal Study With Photovoice Methodology, Alex Vazquez-Cortes, Dierdre Mckay, Connie Tran, Bridget Bugla, Tiffany Bui, Kaisa Holt, Anthony Phan, Clare Hansen, Amy Lin, Amanda Braley, Lisa Marriott Phd

Student Research Symposium

Historically, the underrepresentation of individuals from disadvantaged backgrounds, disabled, and diverse racial/ethnic groups in STEM fields is prevalent. Equity in stem fields allows for different perspectives and knowledge backgrounds allows for the cognitive diversity needed to tackle complex research topics. The Knight Scholars Program (KSP) aims to support underrepresented and disadvantaged high school and undergraduate students pursuing a research career by teaching them the tools they need to succeed. Spanning over three summers, KSP utilized the Self-Determination Theory (SDT) of motivation to create an inclusive learning environment and to strengthen the high schoolers' motivation to pursue research careers focusing on …

Evaluation Of Sleep Outcomes After Traumatic Brain Injury In Children Using Questionnaires And Actigraphy, Connie Tran, Sydney Weese, Cydni Williams Md

Student Research Symposium

Traumatic brain injuries are the result of a sudden external blunt force to the brain and can result in long-term complications or death. In pediatrics, it is the leading cause of acute and chronic sleep wake disturbances, as well as cognitive deficits, which can lead to a reduction in the quality of life. These impairments can later result in lowered performance in work and school settings or decreased psychosocial function. Although there is sufficient evidence that traumatic brain injuries contribute to is that it is unknown whether or not sleep wake disturbances contribute to an increase in the mentioned cognitive …

Hide & Cru-Seq: Investigating Potential Crucivirus Hosts With Fluorescently Labeled Protein, Marcell Devaune Richard, Nacho De La Higuera, Jono Abshier, Ken Stedman

Student Research Symposium

Cruciviruses are DNA viruses that contain a capsid protein that shares striking similarities to capsid proteins from RNA viruses. Formerly known as “RNA-DNA hybrid viruses”, this novel type of viruses suggest gene exchange between unrelated RNA and DNA viruses. However, the hosts of cruciviruses remain unknown. To investigate this groundbreaking virus genome further, utilization of the predicted viral host recognition domain (P-domain) fused to a thermal green protein and a histidine tag, allows investigation of crucivirus hosts in environments where these viruses have been discovered. Using cruciviruses that have been found in soil samples on the PSU campus, along with …

S100b As A Protein Marker For Intracranial Hemorrhages, Anthony Phan

Student Research Symposium

This study aims to evaluate the effectiveness of S100B as a protein marker for patients that are clinically diagnosed with an Intracranial Hemorrhage (ICH). This study enrolled patients that present to the hospital as a trauma activation consistent with a traumatic brain injury (either a blunt or penetrating traumatic mechanism) who are 15 or older, GCS of 12 or lower, and received the placebo arm of the TXA drug. The S100B level of patients will be measured through an Enzyme-Linked Immunosorbent Assay (ELISA). After the data collection, a statistical test will be conducted to determine the level of significance for …

Exploring Speech Experiences, Cpib Scores, And Aac Assessment Experiences Of Autistic Aac Users With Intermittent, Unreliable, Insufficient, And/Or Expensive Speech, Karina Rayl, Pang Lee Herr, Brandon Eddy, Amy Donaldson, Stephanie Fuller, Alyssa Zisk

Student Research Symposium

There is growing evidence from the perspectives of speaking autistic people that augmentative and alternative communication (AAC) supports their self-expression and communicative agency. Despite the evidence supporting the communication effectiveness of AAC, autistic adults have reported that professionals often prioritized speech as the ideal communicative method rather than offering AAC as a communication option. This study will investigate autistic adults’ AAC assessment experiences and explore whether a modified version of the Communication Participation Item Bank (CPIB) self-rating questionnaire could be an effective tool to document the internal states of intermittent, unreliable, insufficient, and/or expensive speech. Surveys will be distributed to …

Second Language Impacts On First Language Processing, Natalie Robison, Sarah C. Creel, Sarah Elkington, Judith Kelholt, Amy Lin, Carolyn Quam

Student Research Symposium

This line of research investigates attrition (loss of fluency) of native Mandarin language (L1) proficiency with increasing proficiency in English. English uses pitch to denote intonation (e.g., “it’s there?” versus “it’s there!”), while Mandarin uses pitch to indicate word meanings; e.g., /he/ means “drink” with a high, level tone, or “river” with a rising tone. The present study delineates between two alternative explanations for the prior finding (Quam & Creel, 2017) that English proficiency correlates with attrition of Mandarin tones, but not vowels. This pattern could be explained by 1) language assimilability (L1-L2 Assimilability Hypothesis), or 2) by tone being …

Describing Shen & Shen Ming Via A Hybrid Quantum Computational Model, Alex M. Cullen, Johnny Lemau

Student Research Symposium

Definitions for Traditional Chinese Medicine (TCM) terminology within the context of quantum biology (QB) have recently been proposed. These definitions aim to elucidate concepts such as qi meridians in TCM. Our study presents a hypothesis that seeks to provide an operational definition for Spirit (Shen) and Bright Spirit (Shen Ming) in TCM via a scoping review. We propose that Shen represents physical, phenomenological proto-consciousness/consciousness in the forms of computation, such as singular particles/bits/qubits, computers, organisms, or computational strategies, whereas Shen Ming may refer to emergent, quasi-physical meta-proto-consciousness/consciousness formed by coherent relationships of multiple orchestrated/integrated units of computation; manifesting itself as …

Impact Of Mindfulness-Oriented Recovery Enhancement On Pain And Disability In Patients With Chronic Lumbosacral Radiculopathy: Results From An Rct, Danielle Zuzero

Student Research Symposium

Lumbosacral Radiculopathy (LR), also known as sciatica, is a common type of radiating neurologic pain in the lower extremities with an estimated lifetime prevalence as high as 43%. The goal of this randomized control trial was to determine the impact of virtually delivered Mindfulness-Oriented Recovery Enhancement (MORE) on patients with LR. Participants were randomized to MORE sessions or treatment-as-usual (TAU) for 8 consecutive weeks, pain intensity was collected daily via email. At baseline and follow-up visits, participants completed questionnaires of disability, quality of life, depression, mindful interpretation of pain, and train mindfulness. Patients undergoing MORE sessions had greater improvement in …

Impact Of Testosterone Therapy On Voices In Trans-Masculine People: A Scoping Review, Samuel E. Hedine, Jeff Conn, Deanna Britton

Student Research Symposium

Treatment of trans people by speech-language pathologists (SLPs) dates back to at least the 1980s. However, the majority of early research on the voices of trans people focused on trans-women. More recently, the field of speech-language pathology has garnered more interest in the effects of testosterone therapy in trans-masculine individuals. The goal of this project is to review current research, and compile the known effects of testosterone therapy in the trans-masculine population on common acoustic indices of voice production, including fundamental frequency (pitch), decibels/sound pressure level (dB SPL; loudness) and cepstral peak prominence (voice quality). A scoping literature search was …

Construction And Mutagenesis Of Ssv1 Mutants In Extreme Viruses, Lou Ann F. O'Connor, Jono Abshier, Kenneth M. Stedman

Student Research Symposium

Archaeal viruses with unique structures such as spindle-shaped virions are found abundantly in extreme environments like geothermal hot springs around the world. Among all spindle-shaped viruses, the model Sulfolobus Spindle-shaped Virus 1 (SSV1) is best studied. Creating the lemon-shaped or spindle-shaped virion structure are two proteins, VP1 as the major capsid protein, and VP3 as the minor capsid protein. The primary structure of VP1 consists of a proteolytic cleavage site at position 66 that is believed to be necessary for virus evolution. Recent studies showed that genetic mutation of the amino acid, glutamate (E) at position 66 in VP1 which …

Feesability Of Laryngeal Endoscopy Simulation Labs In Student Training: A Scoping Review, Anna Thut

Student Research Symposium

Fiberoptic Endoscopic Evaluation of Swallowing (FEES) involves passing a flexible endoscope through the nose and down the throat to provide a detailed view of the throat, airway, and vocal folds. With the scope in place, people can eat and drink, allowing the clinician to evaluate for safe swallowing. Speech-Language Pathologists (SLP) use FEES for diagnostic evaluation and to gauge therapy progress and effectiveness. Simulation training on a low or high-fidelity model may provide a bridge for SLP graduate students to gain competency before being introduced to FEES in a clinical setting. This review aims to gather evidence on the use …

Respiratory-Swallowing Coordination In Motor Neuron Disease: A Scoping Review, Mariam Z. Mansoor

Student Research Symposium

Respiratory-swallowing coordination (RSC) is essential for providing efficient breathing and optimal swallowing function. Most commonly used methods of measuring RSC include nasal thermistry, and respiratory inductance plethysmography (RIP) to determine direction and durations of airflow. Outcome measures include swallow apnea duration (SAD) and respiratory phase pattern (RPP), i.e., direction of airflow pre- and post-SAD. The goal of the current project was to conduct a scoping literature review of RSC, focusing on the motor neuron disease (MND) population, including people with amyotrophic lateral sclerosis (ALS). A multi-engine literature search was conducted in 2023-24 via PubMed and Google Scholar. No limitations were …

Considering The Historical And Systemic Context, To What Extent Are Cuban Women’S Healthcare And Reproductive Rights Affected By The Privacy And Social Influence Of Cuba Today?, Autumn Cowell

Student Research Symposium

This paper will examine how historical and systemic values continue to frame social influences thus impacting Cuban women’s healthcare and reproductive rights. If the impact of history and systems still affects social influences then Women’s Healthcare and Reproductive Rights may be compromised. This investigation will highlight the potential benefits and risks of historical and systemic values that have affected challenges or changes within Cuban culture. And how these social influences are found within the areas of prevention, intervention, and treatment. This paper hopes to outline how the Cuban government and society are sustaining the protection of Cuban women’s access to …

Systematic Comparison Of Propensity Score Matching And Structural Causal Modeling For Clinical Applications, With A Case Study Of Albumin Treatment For Acute Kidney Injury (Aki) Patients: Propensity Score Matching Vs. Structural Causal Models, Layaal Khellah

Student Research Symposium

Introduction:

Propensity Score Matching (PSM) and Structural Causal Models (SCMs) are key approaches in causal inference for treatment evaluation and clinical decisions, both rooted in the potential outcome framework but differing in their foundations—PSM follows Rubin's Causal Model, while SCMs adhere to the Structural Theory of Causation.

Methods:

Our study compares PSM and SCMs in clinical contexts, focusing on albumin as an AKI treatment. We examine each method's steps, highlighting differences. Using data from AKI patients with cirrhosis, we assess albumin’s treatment efficacy with both PSM and SCMs, offering insights into their performance in estimating causal effects..

Results:

PSM and …

Cognitive And Economic Development, John Luke Gallup

OHSU-PSU School of Public Health Annual Conference

A burgeoning literature finds that early childhood risk factors have large causal effects on individuals' cognitive development, education and earnings, but has not assessed the impact on the economy as a whole.

Cognitive ability is the foundation of human capital and the capacity to learn. The risk factors for poor cognitive development are very high in many countries. Each risk factor also causes child mortality, making child survival a viable proxy for good cognitive development conditions. The cognitive development of current workers happened decades earlier when they were children, providing a predetermined correlate. Controlling for country characteristics, income levels and …

Knowledge Of Medicaid Expansion To Recent And Undocumented Immigrants Among Oregon Mexican-Origin Latinos: (Work In Progress), Nancy Ledezma, Grace Parra, Alejandra Nunez, Dr. Blair Darney

OHSU-PSU School of Public Health Annual Conference

Background

Recent and undocumented immigrants are explicitly excluded from federal Medicaid and state insurance exchanges. The first phase of Healthier Oregon was implemented in July 2022 and expanded Medicaid (OHP) benefits to undocumented immigrants ages 19-25 or 55 and older. The second phase was implemented in July 2023 and extended benefits to everyone regardless of age. We assessed understanding of Healthier Oregon among Mexican-origin Latinos. We hypothesize that many potentially eligible people may not know about the program, if they qualify, or how to apply.

Methods

This is a cross-sectional study in collaboration with the General Consulate of Mexico. Our …

Understanding Variation In Provider Referral Rates To Early Intervention For Children With Developmental Delays, Gabriella Tangkilisan, Zoe Kilmer, Michelle Owens, Benjamin Sanders, Katharine Zuckerman

OHSU-PSU School of Public Health Annual Conference

Background:

Early detection and treatment of developmental disabilities (DD), including Autism Spectrum Disorder (ASD), improves language, IQ, and adaptive outcomes. Guidelines recommend immediate referral to Early Intervention (public developmental therapy services) upon positive ASD/DD screening in infant/toddler well child checks. However, children screening positive for ASD/DD are not always referred for Early Intervention services. This project aimed to understand why pediatricians do and do not refer children with positive DD/ASD screens to early intervention.

Methods:

We conducted qualitative interviews with pediatricians who participated in a randomized trial investigating family navigation for children with autism risk. We determined pediatrician referral rates …

A Window Of Opportunity: Describing Participants Engaged In A Comprehensive Perinatal Care Model To Treat Substance Use Disorder During Pregnancy, Christina Jäderholm

OHSU-PSU School of Public Health Annual Conference

In 2019, 12% of pregnant persons were estimated to use psychoactive substances, the highest rate in US history. Substance use disorder (SUD) is a chronic, relapsing condition, and while pregnancy presents a unique opportunity for SUD intervention, research on pregnant and postpartum SUD patient experiences is vital for informing perinatal systems of care. The purpose of this presentation is to describe a sample from SUN, a comprehensive perinatal care program for pregnant persons with SUD in North Carolina.

Methods

We abstracted medical records (n=29), surveyed participants (n=29), and conducted two focus groups (n=7). Medical records provided participant demographics; medical, social, …

Gaza's Healthcare System In Collapse: An Exploratory Analysis Of Healthcare Attacks In Occupied Palestinian Territories (Opts) And Israel Since October 2023, Vincenzo J. Cornacchione

OHSU-PSU School of Public Health Annual Conference

Decades of apartheid practices and oppression in Occupied Palestinian Territories (OPTs), marked by mass displacement, restricted access to essential services, and countless human rights violations, have culminated in today's systematic dismantling of Gaza’s healthcare infrastructure. To investigate the systematic obstruction of healthcare access in OPT, this exploratory analysis employs an open intelligence dataset containing event data on reported healthcare attack incidents in OPT and Israel since October 2023. Specifically, this analysis seeks to elucidate the nature and extent of healthcare attacks in OPT by answering student-defined research questions, based on a priori expectations around the data. The analysis confirms that …

Impact Of Two Shift Schedules On Post-Shift Blood Pressure In Firefighters, Ayeisha H. Haswarey

OHSU-PSU School of Public Health Annual Conference

Background: Firefighters have an increased risk of cardiometabolic disease compared to the general population. Blunted blood pressure (BP) dipping during nocturnal sleep is associated with increased cardiometabolic disease morbidity/mortality. Shift work can alter diurnal BP oscillation, but the extent of alteration by different schedules remains debated. No study to date has examined firefighting shift schedules, necessitating a longitudinal evaluation to begin to understand their implications for cardiometabolic health. Thus, this preliminary analysis compares how two common schedules (24/48 hours on/off vs. 1/3/2/3 days on/off) impact post-shift BP and dipping in 20 firefighters.

Methods: 20 participants (10% female; 25-54 years of …

Transgender And Non-Binary Health In Oregon Under A Single-Payer Health System, Amy (Mick) L. Mcveety (They/She)

OHSU-PSU School of Public Health Annual Conference

As the state with the highest percentage of population who identifies as LGBTQ+, Oregon has a duty to provide adequate health protections and services to its transgender and nonbinary (TGNB) residents, particularly given the disparities TGNB individuals face in housing, employment, education, and health. Following recommendations from the Oregon Joint Task Force on Universal Health Care, Oregon should implement a single-payer health care system, with particular attention to:

1. Protecting patient privacy in EHR and other systems, particularly for youth TGNB patients;
2. Expanding the covered gender-affirming services and removing barriers such as cost-sharing and prior authorization, and;
3. Recruiting TGNB providers and …

Gender Affirming Surgery And Pain In Adolescents: Teen And Parent Experiences, Corrin Murphy, Eleanor Battison, University Of Rhode Island, Anna Wilson Phd

OHSU-PSU School of Public Health Annual Conference

Background: Adolescents seeking gender affirming medical care face unique biopsychosocial challenges, including experiences of discrimination and stigma. Transgender and gender diverse (TGD) adolescents often undergo gender affirming surgery (GAS). While there is an increase in GAS for TGD adolescents in the U.S., little is known about the pain experiences in the post-surgical period among these youth. There have been no studies to our knowledge that examine the psychological functioning of parents and their ability to handle their child's distress, which may be affected by their child's post-GAS pain experiences. Parental responses to their children’s pain and distress may, in turn, …

Exploring Decolonial And Indigenous Mental Health Framework And Practice To Address Complex Trauma Among Palestinian Youth Living Under Violence Of Settler-Colonialism, Vivian L. Duong, Corrin Murphy

OHSU-PSU School of Public Health Annual Conference

The growing settler colonial project of Israel forced indigenous Palestinians to flee from their homeland to further the Zionist movement of establishing a Jewish-majority state. The forced dispossession and displacement of Palestinians at this time was referred to as the Nakba, or catastrophe (Masalha, 2002). From 1947 and 1949, approximately 750,000 Palestinians from a population of 1.9 million were made refugees (Al Jazeera, 2017). Also referred to as the ethnic cleansing of Palestine, Zionists forcibly took over 78 percent of Palestine, destroyed about 530 villages and cities, and killed around 15,000 Palestinians including more than 70 massacres (Al Jazeera, 2017). …

Inequities In Chronic Stress Exposure At The Intersection Of Race, Gender, And Sexual Identity In A Nationally Representative Sample Of U.S. Adults, Jordan M. Lancaster, Efrain H. Chavez Martinez

OHSU-PSU School of Public Health Annual Conference

Background

Social inequity rooted in systemic oppression is robustly associated with mental and physical health; chronic stress is highlighted as a key mechanism. Limited research examining the association between sexual identity alone and C-reactive protein (CRP) – an upstream biological marker of chronic stress exposure – has yielded mixed results.

Purpose

To examine whether race/ethnicity, gender, and sexual identity interact to produce unequal levels of CRP.

Methods

Using cross-sectional data from the 2003-2010 waves of the National Health and Nutrition Examination Survey, we examined intersectional (self-reported race*gender*sexual identity) patterns in log-transformed CRP levels using a multivariable linear model among 10,885 …

Strong Hearts Program: The Results Of A Novel Primary-Care Based Diagnostic And Referral Program For Chagas Disease In East Boston, Ma, Usa, Javier J. Huerta

OHSU-PSU School of Public Health Annual Conference

Purpose: Chagas disease (CD), a neglected parasitic infection, affects ~300,000 people in the US. Untreated, CD leads to irreversible cardiac morbidity and death in 20-30% of cases, yet

Methods: After provider and community sessions, 14,354 patients were screened at EBNHC from March 2017 - May 2023, following a prespecified protocol. Confirmed Chagas patients were referred to Boston Medical Center for further evaluation. Using chi-squared tests, we analyze diagnostic uptake and prevalence stratified by demographics. Additionally, we abstracted care continuum barriers from Chagas patients' records.

Results: Per quarter, a median of 572 patients were screened (IQR: 393 – 712). …

The Association Between Acculturation & C-Reactive Protein In U.S. Immigrants: A Cross-Sectional Study, Jessica Kilinski Bs, Rosol Mikail Bs, Kelly M. Reavis Phd, Mph, Deborah Karasek Phd, Mph

OHSU-PSU School of Public Health Annual Conference

Purpose: Immigrants undergo acculturation as they assimilate to a different culture, potentially leading to immense stress. Our objective was to examine the association between acculturation and C-reactive protein (CRP), a marker of stress-induced inflammation. We hypothesized that U.S. foreign-born adults 20 years and older with higher degrees of acculturation would have higher CRP levels compared to those with lower acculturation.

Method: We used 2017-2018 National Health and Nutrition Examination Survey (NHANES) data from 1526 participants to conduct a cross-sectional analysis. We measured acculturation as language spoken at home (categorized as low, moderate, and high) and examined its association with CRP …

The Use Of Extreme Risk Protection Orders Intended To Prevent Mass Violence In Oregon: A Descriptive Study, Rosol Mikail, Rebecca Valek, Shauna Rakshe, Rebecca Teichman, Susan Defrancesco, Kathleen Carlson

OHSU-PSU School of Public Health Annual Conference

Purpose: Firearm violence is a critical public health issue in the United States. Extreme Risk Protection Order (ERPO) laws are an intervention method that have been enacted in many states to prevent firearm violence including mass violence threats. This study examined the characteristics of ERPO petitions filed in Oregon for a 6-year period that involved mass violence threats.

Method: ERPO petitions included in court records obtained through the Oregon Judicial Case Information Network, from January 1, 2018, to December 31, 2023 were abstracted; a 20% random sample of records was double-coded to ensure interrater reliability. An epidemiologic analysis of cases …

Impact Of Medical Formula Shortage On Patients With Inborn Errors Of Metabolism (Iem) And Their Dietitians, Haemin Lee

OHSU-PSU School of Public Health Annual Conference

Since Feb. of 2022, patients with inborn errors of metabolism (IEM) suffered medical formula shortages due to an abrupt shut down of a major formula company in the US. The goal of this project was to understand the nutritional and psychosocial impacts on patients with IEM and changes in patient-dietitian relations as a result of the unexpected formula shortage.

Two survey were set up and disseminated via REDCap to patients(18 years-old or older), parent/legal gurdian of patients in the US, from Dec.2023-Jan.2024. Of those 571 records, 139(60.4%) patient surveys and 166(48.7%) caregiver surveys were retained for analysis after dropping complete …