Open Access. Powered by Scholars. Published by Universities.®

Medicine and Health Sciences Commons

Open Access. Powered by Scholars. Published by Universities.®

PDF

Philadelphia College of Osteopathic Medicine

Aspirin

Articles 1 - 2 of 2

Full-Text Articles in Medicine and Health Sciences

Is There A Mortality Benefit With The Use Of Aspirin In The Primary Prevention Setting In Adults Without Cardiovascular Disease?, Lauren Bernardi Jan 2020

Is There A Mortality Benefit With The Use Of Aspirin In The Primary Prevention Setting In Adults Without Cardiovascular Disease?, Lauren Bernardi

PCOM Physician Assistant Studies Student Scholarship

OBJECTIVE: The objective of this selective EBM review is to determine whether or not there is a mortality benefit with the use of aspirin in the primary prevention setting in adults without cardiovascular disease.

STUDY DESIGN: This is a systematic review of three double blind randomized controlled trials published in 2018. All three trials compared 100 mg of aspirin with placebo and were published in English.

DATA SOURCES: All three articles were identified and published through peer-reviewed sources using PubMed.

OUTCOMES MEASURED: Mortality was the outcome measured through various death identification steps such as review of death certificates, notification from …


Is Aspirin Effective In Helping To Prevent Breast Cancer In Women Ages 45 Years And Older?, Kristen M. Quartuccio Jan 2012

Is Aspirin Effective In Helping To Prevent Breast Cancer In Women Ages 45 Years And Older?, Kristen M. Quartuccio

PCOM Physician Assistant Studies Student Scholarship

OBJECTIVE: The objective of this selective EBM review is to determine whether or not aspirin is effective in helping to prevent breast cancer in women ages 45 years and older.

STUDY DESIGN: Review of three English language primary studies published in 2005, 2007, and 2008

DATA SOURCES: Two randomized, double blind, placebo controlled clinical trials and one prospective, population based cohort study comparing aspirin to placebo were found using PubMed and Cochrane databases.

OUTCOMES MEASURED: Breast cancer development was measured in several ways. Tumor characteristics were measured at diagnosis, including size, metastasis to lymph nodes, histology of the mass, histology …