Medicine and Health Sciences Commons^™

Digest Of The Philadelphia College Of Osteopathic Medicine (Fall 2009), Philadelphia College Of Osteopathic Medicine

Digest

The Fall 2009 issue of the Digest of the Philadelphia College of Osteopathic Medicine includes the following articles:

• Opening Remarks
• PCOM Updates and Kudos
• PCOM–World’s Oldest College of Osteopathic Medicine
• Helping Patients During Difficult Times
• Global Outreach Inspires Students
• Class Notes
• In Memoriam
• My Turn Essay
• PCOM Events

Expression Of Transcription Factor Zinc-Binding Protein-89 (Zbp-89) Is Inhibited By Inflammatory Cytokines., Ruth C. Borghaei, Mariah Chambers

PCOM Scholarly Papers

Zinc-binding protein-89 (ZBP-89; ZNF148, BERF-1, BFCOL-1) is a zinc-finger transcription factor of the Kruppel family. It has been shown to regulate the expression of a number of genes, acting as either an activator or repressor of gene expression, depending on the context. It is over-expressed in several cancers, but has been shown to be involved in apoptosis and to have a negative influence on cell growth in part by interactions with p53. Previously, ZBP-89 was shown to activate transcription of the matrix metalloproteinase-3 (MMP-3) gene by binding to a polymorphic promoter element in competition with nuclear factor kappaB (NF-kappaB). NF-kappaB …

Digest Of The Philadelphia College Of Osteopathic Medicine (Summer 2009), Philadelphia College Of Osteopathic Medicine

Digest

The Summer 2009 issue of the Digest of the Philadelphia College of Osteopathic Medicine includes the following articles:

• Opening Remarks
• PCOM Updates and Kudos
• Development News
• GA-PCOM Mason W. Pressly Memorial Medal
• Crisis in the ER: Repairing the Nation’s Health Care Safety Net
• Challenges
• Finding Answers
• Physician Assistants Ease Burden
• Primary Care Physicians Are Key
• PCOM Provides Leadership
• Reunion Years Roundtable
• The Inspiration Behind the Simmy Ginsburg Humanitarian Award
• Class Notes
• In Memoriam
• My Turn Essay
• PCOM Events

Digest Of The Philadelphia College Of Osteopathic Medicine (Winter 2009), Philadelphia College Of Osteopathic Medicine

Digest

The Winter 2009 issue of the Digest of the Philadelphia College of Osteopathic Medicine includes the following articles:

• Opening Remarks
• PCOM Updates and Kudos
• Development News
• Keeping the Balance True: The Rural Medicine Practice
• Health and Social Service Outcomes
• The Effects of Physician Supply
• Specialty-Specific Issues: Obstetrics and Gynecology
• Federally Qualified Health Centers for Direct Provision of Care
• Rural Sociology and the Draw for Today’s Medical Students
• Founders’ Day 2009
• O.J. Snyder Memorial Medal
• Mason W. Pressly Memorial Medal
• Preparing Medical Students for End of Life Care
• Class Notes
• In Memoriam
• My Turn Essay
• PCOM Events

Catalog (2009 - 2010), Philadelphia College Of Osteopathic Medicine

Catalogs

A snapshot of the PCOM curriculum throughout the decades.

Synapsis: Philadelphia Campus (2009), Philadelphia College Of Osteopathic Medicine

All Yearbooks

This yearbook includes Clubs, White Coat Ceremony, D.O. Day on the Hill, OMM Fellows, Military, Charity, Runner's Club, Soccer, Volleyball, Flag Football, Baseball, Cycling, Deck Hockey, Men's Rugby, Basketball, Prom, Parties, Student Government Association, Class Officers, A Capella, American College Of Osteopathic Family Practitioners, ACOFP, American Holistic Medical Association, AHMA, American Medical Association, American Medical Student Association, Association Of Military Osteopathic Physicians and Surgeons, AMOPS, American Medical Women's Association, AMWA, Christian Medical Association, Kappa Sigma Phi, KSPh, (ΚΣΦ), Kappa Sigma Phi Women's Osteopathic Society, Lesbian Gay Bisexual Transgender People in Medicine, National Latino Health Organization, Phi Sigma Gamma, PSG, (ΦΣΓ), …

Synapsis: Georgia Campus (2009), Philadelphia College Of Osteopathic Medicine

All Yearbooks

This yearbook includes the White Coat Ceremony, Accreditation, Student Government Association, Class Officers, Clubs, PCOM Learning About Youngsters, PLAY, Emergency Medicine.

Does The Duration Of Type 2 Diabetes Correlate With Changes In Taste Deficits?, Ann T. Mclaughlan

PCOM Biomedical Studies Student Scholarship

The loss of insulin sensitivity in Type 2 diabetes interferes with cellular utilization of glucose. The underlying down-regulation of insulin receptors and the resulting insulin resistance is wide-spread throughout the body. The cardiovascular consequences may be indirectly responsible for decreased taste sensitivity because of diminished perfusion of the taste buds in this patient population. This study utilized an inexpensive, non-invasive technique, electrogustometry, to directly stimulate the taste buds by applying a variable, direct-current stimulus to measure taste receptor thresholds in newly-diagnosed ( < 2 years) and long-standing diagnosed (> 6 years) male and female Type 2 diabetes mellitus subjects. Taste thresholds were elicited by application of an …

Confronting The Unknown: Mothers’ Reactions, Challenges, And Ways Of Coping With A Child's Diagnosis Of Long Qt Syndrome, Twain Gonzales

PCOM Psychology Dissertations

Long QT syndrome (LQTS) is a life-threatening inherited cardiac condition. It is caused by a disturbance in the ion channel genes that control cardiac repolarization, resulting in ventricular arrhythmias that can lead to syncope, sudden cardiac arrest (SCA), or sudden cardiac death (SCD). Most deaths occur in children, adolescents, and young adults. Although congenital LQTS occurs in 1/3000 to 1/5000 individuals, to date, little research has been conducted on the psychosocial effects of LQTS. Mothers who are confronted with a new diagnosis of their children’s LQTS are likely to have never heard of the disease prior to diagnosis, and few …

Rhoa/Rho-Kinase Signaling: A Therapeutic Target In Pulmonary Hypertension, Scott A. Barman, Shu Zhu, Richard E. White

PCOM Scholarly Papers

Pulmonary arterial hypertension (PAH) is a devastating disease characterized by progressive elevation of pulmonary arterial pressure and vascular resistance due to pulmonary vasoconstriction and vessel remodeling as well as inflammation. Rho-kinases (ROCKs) are one of the best-described effectors of the small G-protein RhoA, and ROCKs are involved in a variety of cellular functions including muscle cell contraction, proliferation and vascular inflammation through inhibition of myosin light chain phosphatase and activation of downstream mediators. A plethora of evidence in animal models suggests that heightened RhoA/ROCK signaling is important in the pathogenesis of pulmonary hypertension by causing enhanced constriction and remodeling of …