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Philadelphia College of Osteopathic Medicine

Theses/Dissertations

2020

Acne

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Is Spironolactone An Effective Method For Reducing Lesion Count In Individuals With Acne Vulgaris?, Alana M. Waters Jan 2020

Is Spironolactone An Effective Method For Reducing Lesion Count In Individuals With Acne Vulgaris?, Alana M. Waters

PCOM Physician Assistant Studies Student Scholarship

OBJECTIVE: The objective of this selective EBM review is to determine whether or not “Is spironolactone an effective method for reducing lesion count in individuals with acne vulgaris?”

STUDY DESIGN: A systematic review of three English language studies published after 2009 in peer-reviewed journals, including two randomized, controlled trials and one retrospective cohort study.

DATA SOURCES: Two randomized, controlled trials and one retrospective cohort study that evaluated spironolactone as a treatment for acne vulgaris were found using PubMed.

OUTCOMES MEASURED: Reductions in total lesion counts (TLC).

RESULTS: All three studies supported the efficacy of spironolactone in reducing lesion counts in …