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Medicine and Health Sciences Commons

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Otterbein University

Theses/Dissertations

2016

Dantrolene

Discipline

Articles 1 - 2 of 2

Full-Text Articles in Medicine and Health Sciences

Malignant Hyperthermia, Taylor M. Morriss Aug 2016

Malignant Hyperthermia, Taylor M. Morriss

Nursing Student Class Projects (Formerly MSN)

Complications related to the anesthetic process are multifaceted and abundant. As a future nurse anesthesia student, the underlying pathophysiology, diagnosis, and treatment of anesthesia-related complications are of particular interest. One such anesthesia-induced life-threatening metabolic process involves the hypermetabolism of skeletal muscle. This pharmacogenetic process, known as malignant hyperthermia (MH), has a variable incidence rate ranging from 1:10,000 to 1: 250,000 anesthetic cases. However, the prevalence of the genetic abnormalities may be as great as one in 400 individuals (Rosenberg, Pollock, Schiemann, Bulger, & Stowell, 2015, p. 1). “Malignant hyperthermia (MH) is a rare, but life-threatening, autosomal-dominant inherited disorder that may …


Malignant Hyperthermia, Leonid Levertov Jul 2016

Malignant Hyperthermia, Leonid Levertov

Nursing Student Class Projects (Formerly MSN)

Providing patient care in the operating room as a nurse anesthetist is rewarding and challenging. There is a paramount level of responsibility that lies on certified registered nurse anesthetist (CRNA). Recognition of serious life threatening conditions by CRNA must be prompt and treated urgently. As a student registered nurse anesthetist and future CRNA, knowing how to recognize and treat developed emergency conditions while patient is under anesthesia or recovering from anesthesia is an absolute requirement. Malignant hyperthermia (MH), is a rare autosomal dominant hypermetabolic life threatening disorder of skeletal muscle. Malignant hyperthermia is caused by volatile anesthetics (desflurane, sevoflurane, isoflurane) …