Medicine and Health Sciences Commons^™

Promoting The Use For Sugammadex In Robotic- Assisted Surgeries:, Amr Ali

Scholars Week

No abstract provided.

Benefits Of The Use Of Probiotics In Preventing Secondary Infections, Sarah Cutcher

Scholars Week

Through evidence based research, the use of supplemental probiotics has been shown to have a positive effect in preventing secondary infections in hospital patients. Although there are other techniques that have decreased the incidence of infections, such as reducing invasive procedures and aseptic techniques, these are external procedures designed to prevent infection. Probiotics are an effective method of internally preventing infection. By studying certain infections and the effect that probiotics have on their prevention, researchers can safely conclude which bacteria strain could help to prevent each infection. Some different types of issues that will be looked at are healthcare acquired …

The Impact Of Spirituality On Patient Outcomes And How Nurses Can Implement Spirituality In Patient Care, Audrey Pittman

Scholars Week

This article studied the impact of spirituality on patient outcomes and how nurses can implement spirituality into patient care. This study looked at peer reviewed articles over the impact of spirituality on patient care. They found a positive impact of spiritual wellness and patient outcomes. Next it looked at how nurses could implement spiritual care into practice. This study found that the implementation of the FICA assessment tool would be a great first step in the right direction on no longer neglecting spiritual wellness.

Local Anesthetic Systemic Toxicity (Last): Provider Education, Alexis Johnson

Scholars Week

Abstract

Background: Local Anesthetic Systemic Toxicity (LAST) is a rare but serious complication due to accumulation of local anesthetics. If not treated quickly, LAST can cause detrimental complications such as seizures and cardiac arrest. Therefore, it is important that anesthesia providers are well versed in preventing, recognizing, and treating this adverse event.

Methods: A LAST flowchart written by The American Society of Regional Anesthesia and Pain Medicine (ASRA) was printed and placed in each operating room in a small suburban hospital. Anesthesia staff were also educated on recognizing signs and symptoms, onset time, high risk patients, and prevention.

Results: Ten …

Reducing Perioperative Opioid Use Through Utilization Of Dexmedetomidine Prior To Induction: Provider Education, Axel Nilsson

Scholars Week

Reducing Perioperative Opioid Use Through Utilization of Dexmedetomidine

Prior to Induction: Provider Education

Abstract

AIM: The primary objective of this project was to decrease perioperative opioid use by providing education to key stakeholders on the efficacy of implementing dexmedetomidine prior to induction to attenuate the response to surgical stress.

KEYWORDS: anesthesia, dexmedetomidine, opioid-sparing analgesia, multimodal analgesia

METHODS: Strategies to promote a practice change included disseminating education to anesthesia providers through handouts and one-on-one education and evaluating the efficacy of the education through questionnaires.

RESULTS: Twelve anesthesia providers participated in the project. After receiving education, the mean score based on a …

Education Of Ventilator-Associated Pneumonia Prevention In Adult Intensive Care Patients, Carlin Morgan

Scholars Week

The purpose of this project was to improve knowledge related to evidence-based ventilator-associated pneumonia (VAP) preventative measures that decrease the prevalence of VAP in adult patients in the intensive care unit (ICU). An educational presentation was provided to twelve critical care nurses at a 349-bed hospital in western Kentucky. A pretest was obtained to measure the nurse’s knowledge prior to the presentation. A PowerPoint and pamphlet containing VAP prevention techniques were presented to the twelve critical care nurses during each meeting. A posttest was then administered after the presentation to measure the efficacy of the educational presentation. The mean of …

Avaren-Fc, A Novel Immunotherapeutic, Recruits Nk Cells In B16f10 Melanoma Tumor Tissue, Sreevatsa Vemuri, Katarina Mayer, Nobuyuki Matoba

Posters-at-the-Capitol

Melanoma is the fifth most common cancer in the US, with limited effective immunotherapeutic options available for patients. Avaren-Fc (AvFc) is a novel experimental immunotherapeutic agent with a unique “lectibody” property. It is capable of targeting cancer cells through the selective recognition of high mannose glycans, which are aberrantly overrepresented on the surface of malignant cells. AvFc can interact with circulating effector immune cells equipped with Fc receptors, such as natural killer (NK) cells to induce antibody-dependent cell-mediated cytotoxicity (ADCC) and kill cancer cells. Previous work has shown that AvFc effectively induces ADCC activity against B16F10 cancer cells in vitro …

Enhancing The Safety Of Medication Administration: The Synergistic Role Of Closed Loop Electronic Medication Management And Iv Medication Administration, Kelly Goetz, Angela Schoenung, Lauren Daugherty, Kaitlyn Hornsby

Posters-at-the-Capitol

The high acuity of patients in the ICU results in numerous medications being administered, increasing the risk of medication errors. The purpose of this project is to investigate the impact of integrating consistent closed loop electronic medication management (CLEMM) to decrease medication errors in the ICU for bedside nurses who use electronic health records (EHRs). The project type is a comprehensive literature review, with studies that included a single prospective cohort study, case report, single non-randomized trial, quasi experimental study, single cross-sectional studies, and systematic reviews. The importance of this project is to address the break in the loop of …

The Addition Of Nature To The Patient's Healing Regimen, Katelyn Lewis, Audrey Henry

Scholars Week

Through our scholarly research, we have found many benefits to the use of nature to help facilitate healing within patients. Our project aims to spread awareness of the positive aspects of nature during the healing process. Specifically, our research focuses on healing gardens and outside therapy for patients. Our presentation is based upon Nightingales' theory of the environment. Our hope is that facilities will implement the addition of nature to the patient's plan of care.

Effects Of Clinical Competency In Nursing Students Following The Implementation Of Student-Led Learning, Cori E. Hack, Jacob N. Hicks

Scholars Week

Research and supporting evidence represent a gap identified in didactic learning between students and faculty. This gap shows emotional factors of the nursing curriculum that may suggest negative impacts on nursing students, but also improvements that can be made to increase students’ clinical competency levels. By adhering to strict definitions of student-led learning theory and clinical competency, we were able to create concrete evidence with measurable data that can contribute to the elimination of this gap in learning. Upon inspection of past text, we identified a need for further research on this topic to bring awareness and encourage this method …

Reducing Burnout Among Pediatric Oncology Nurses, Karlie Devore, Madison Jarvis

Scholars Week

No abstract provided.

The Importance Of Educating Adolescent Mothers In The Postpartum Period, Sydney Price, Madelyn Travis, Reagan Schwable

Scholars Week

Due to the lack of policy or procedure for individualized education for adolescent mothers, we concluded that a educational checklist in the charting system would be the most effective way to properly educate young mothers during this confusing stage in their life. Specific education helps to improve perceived quality of care, safety/wellbeing in the young mother and newborn, and reducing the risks of complications such as postpartum depression or issues with pregnancy later on. In summary, ensuring that teenage mothers are fully educated before discharge will provide for better mother and baby outcomes.

Benefits And Challenges Of Charge Nurses Taking Patient Assignments, Alyssa Kuhl, Jenna Thomas, Karlee Meadows

Scholars Week

No abstract provided.

Implementation Of An Artificial Airway Communication Tool, Grace Thacker, Macy Damron

Scholars Week

This evidence based practice research project evaluated the use of communication tools for patients with artificial airways in the hospital setting. It was determined through clinical experiences and article research that no standard communication tool has been recommended for this patient population. Moreover, research has suggested that patient satisfaction has improved with the use of new communication methods. Given the lack of a solution to this issue, we have suggested the implementation of a new hospital policy concerning the use of a communication tool. This communication tool is an eight and a half by eleven laminated piece of paper that …

The Benefits Of Using Patient Transfer Devices In The Emergency Department, Abby Lawhorn, Mikaylen Dearmond

Scholars Week

The Emergency Department (ED) is known as one of the most fast-paced environments in which nurses work. Because of the nature of their responsibilities and daily tasks, ED nurses are at high risk of injury. One of those tasks that occur multiple times throughout the day is patient transfers. The Emergency Department staff is constantly moving patients in and out of the unit. Most often, patients seen in the ED are weak, in pain, elderly, or unable to transfer from vehicles, ambulance, stretchers, or wheelchairs independently or without minimal assistance. Our research focuses on the benefits of using assistive devices …

Why Bladder Training Prior To Foley Catheter Removal Is Not Best Practice, Emily Winstead, Sydny Tucker

Scholars Week

Several studies have been completed on bladder training prior to foley catheter removal via intermittent clamping. While this practice initially appears to be beneficial to patient care, the studies we have researched all found the practice to be insignificant or not indicated for patient care. As we researched, we were able to compile evidence from multiple sources that support bladder training prior to catheter removal is not best practice. After compiling those results, we were able to gather a better understanding of the reasons this practice is not indicated and what risks it will pose to patients. In conclusion, we …

The Benefits And Use Of Intranasal Versed (Midazolam) In Pediatric Patients Requiring Procedural Sedation And Seizure Cessation In The Emergency Department, Coleman Austin, Madison Simmons

Scholars Week

Pediatric emergency department’s across the country have developed specific methods for treating injuries and illnesses in the pediatric population. However, many adult emergency departments that treat pediatric patients have outdated methods for treating children who come through their doors. A great example of this would be the current standard of care for pediatric patients who are in need of some form of sedation for treatment. Many adult emergency departments currently will use moderate to deep sedation techniques for treatment that should typically only require light sedation, like for lacerations and imaging scans. After lots of research, it seems that where …

Benefits Of Minimizing Foley Catheterization Time In Nursing Homes, Carly Robertson, Laney Farmer

Scholars Week

Foley catheterization is a commonality seen in various healthcare settings. There is a high risk of infection, trauma, and dependence associated with indwelling urinary devices. This research project addresses the benefits of decreasing foley catheterization time, specifically in nursing home patients. Previous research has deemed foley catheters as dangerous, invasive, and in some cases unnecessary. Foley’s are accompanied by many complications, trauma to urinary structures, as well as a major source of infection. This project used meta-analysis nursing journals to support the importance of decreasing catheterization time. This evidence-based practice project has discovered many risks associated with foley catheters and …

Reactive Chlorine Species Reversibly Inhibit Dnab Protein Splicing In Mycobacteria, Daniel R. Wahl, Christopher W. Lennon

Posters-at-the-Capitol

Intervening proteins, or inteins, are mobile genetic elements that are translated within host polypeptides and removed at the protein level by splicing. In protein splicing, a self-mediated reaction removes the intein, leaving a peptide bond in place. While protein splicing can proceed in the absence of external cofactors, several examples of conditional protein splicing (CPS) have emerged. In CPS, the rate and accuracy of splicing are highly dependent on environmental conditions. Because the activity of the intein-containing host protein is compromised prior to splicing and inteins are highly abundant in the microbial world, CPS represents an emerging form of posttranslational …

Screenings To Decrease Pediatric Suicide, Jordan Bridges, Dana Schildmeyer, Amanda Austin, Laura Boesken

Posters-at-the-Capitol

This project aimed to examine the current practice related to mental health and depression screenings in pediatric patients. The benefits of implementing screening in schools in identifying depression and suicide risks sooner were also considered. This project focused on the correlation between earlier mental health screening and identification of these mental health disorders earlier in the life of pediatric patients and suicide rates. Current, published literature notes mental health screening in the pediatric population in schools is an effective method to facilitate monitoring and early intervention in detecting a mental illness. Schools implementing mental health screenings can result in increased …

Home Visitation To Prevent And Reduce Postpartum Depression, Anna Bauer, Madison Polley, Laura Boesken Dnp, Msn, Rn

Posters-at-the-Capitol

Postpartum depression (PPD) occurs in 13-19% of women worldwide, and is a stigmatized medical condition affecting maternal and infantile long term outcomes. The purpose of this evidence-based practice project was to determine if women at high risk for PPD are affected by home visitation programs from discharge up to three years postpartum. CINHAL Ultimate, Google Scholar, and Medline databases were used. Current evidence supports the use of home-visitation programs for postpartum women to decrease the prevalence and the symptoms of PPD by allowing nurses access into homes to provide early intervention for PPD. In addition to providing care for prevention …

Uncovering The Role Of Cancer Associated Fibroblasts In Tumor Immunosuppression, Kamal Amirneni, Kavitha Yaddanapudi

Posters-at-the-Capitol

Current advances in cancer immunotherapy are hindered by the immunosuppressive nature of the tumor microenvironment (TME). Cancer-associated fibroblasts (CAFs) are a key component of the TME that contribute to suppressing the immune response. Chemokines and cytokines released by CAFs, such as IL-6, attract circulating monocytes which are converted into myeloid-derived suppressor cells (MDSCs). MDSCs suppress T-cells and natural killer cell proliferation which inactivates the immune response and deters immunotherapy. Both Prostaglandin E₂ (PGE₂) and granulocyte-macrophage colony-stimulating factor (GM-CSF) have been implicated in the CAF immunosuppressive pathway, but a causal link has yet to be established. We hypothesized …

Phase 1a Clinical Study For Q-Griffithsin Intranasal Spray For Prevention Of Coronavirus, Megan Bezold, Kenneth Palmer, Nobuyuki Matoba, Elizabeth Cash

Posters-at-the-Capitol

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a highly transmissible virus that causes acute respiratory disease with possible long-term complications, known as coronavirus disease 2019 (COVID-19). Griffithsin (GRFT; including the oxidation-resistant variant Q-GRFT used in this study) is an algal carbohydrate-binding protein exhibiting antiviral effects against many enveloped viruses, including all major variants of SARS- CoV-2 reported to date. Q-GRFT has been recombinantly manufactured in Nicotiana benthamiana plants, thoroughly purified, and formulated as an intranasal spray designed to be developed as a non-vaccine broad-spectrum prophylactic product for acute use. This is the first-in-human, randomized, double-blind, placebo-controlled study. The …

Implementing The Practice Of Rns And Uaps Receiving "Hand-Off" Report Conjointly, Gabby Pack, Cora Moll

Scholars Week

This is an informational presentation about ineffective communication within the nursing practice. This presentation outlines the benefits of RNs and UAPs giving/receiving "hand-off" report together.

Decreasing Alarm Fatigue Through Alarm Management Training, Leah Davis, Brittany Fleming

Scholars Week

Alarm fatigue is a notable problem in the hospital setting. Alarm fatigue can decrease nurse response time and desensitize nurses to alarms. When this occurs, patient outcomes begin to be negatively affected. To combat this, we researched multiple articles on alarm fatigue and alarm management programs. These programs would be implemented and nurses would learn how to troubleshoot alarm equipment, how to recognize alarm fatigue, how to prevent alarm fatigue, and many more. Based on research articles, alarm management programs decrease alarm fatigue in nurses and the amount of alarms.

Implementing Hourly Rounding, Kalyn Grice, Emma Durham

Scholars Week

It has been long known that nurses can be stretched thin during their 12 hour shifts. Whether they are running around passing medications, completing orders, or performing nursing interventions the world of nursing is always go, go, go. With this mindset and culture some patients who require less tasks and care may be overlooked and not seen for a few hours during a shift. This can lead to negative patient outcomes and safety problems. Throughout the day patient’s require assistance to meet many different needs, many of them being activities of daily living, like using the restroom, changing positions, brushing …

Improving Patient Medication Teaching With A “Meds-To-Beds” Program, Grace Phelps, Shanna Blocker

Scholars Week

Medication education is a vital part of a healthcare provider’s job. Nurses specifically often must take on the main role in medication education in collaboration with physicians and pharmacists. The current medication education at a certain hospital involves discharging patients with a list of medications, dosages, and instructions. The policy also includes the use of layman terms in discussion and handing the patient a sheet with the date/time of last administration by the nurse. Before discussing a change in policy, it is important to first clarify who must take on the responsibility of medication education . This is within the …

Too Loud: A Project For Sound Reduction In The Neonatal Intensive Care Unit, Peyton Cadwell, Amy Krazl

Scholars Week

Sound levels in any intensive care unit environment are significantly higher than the recommended volume. The neonatal intensive care unit (NICU) is included in this aggregate that frequently exceeds advised levels. There are consequences associated with increased sound, such as slower language development and behavior issues. Not only are babies subjected to physiological effects, but there is potential for psychological detriment as well, such as behavioral issues (Bremmer, 2003). Many solutions for this issue have been proposed, including lowering phone volumes, putting rubber shoes on furniture and switching audio alarms to visual alarms. One specific intervention that may reduce the …

Effective Communication In Dementia Patients, Morgan Loveless, Callie Hardesty

Scholars Week

Effective Communication with Dementia Patients - Abstract

Throughout every nurse’s career, one will have the experience of working with those with dementia. Patients who suffer with dementia require different approaches to communication and may have difficult interactions with healthcare workers. A barrier many nurses continue to endure is poor communication and relationships with dementia patients. Many nurses work at a very quick and stressful pace, putting a strain on many nurses’ relationships with dementia patients. Ineffective communication may lower the quality of care dementia patients receive as nurses may lack the extra time needed to effectively communicate. This can lead …

Breadth Of Vaccinated Cancer Patient Humoral Response To Sars-Cov-2 Spike Protein And Rbd Variants, Julia Corman, Joey Breckenridge Jr., Adrienne M. Bushau-Sprinkle, Krystal T. Hamorsky, Joshua L. Fuqua

Posters-at-the-Capitol

SARS-CoV-2, the virus responsible for the COVID-19 of which several variants have emerged, such as the B.1.351 SARS-CoV-2 variant. The Receptor Binding Domain (RBD), located within the Spike protein is an immunogenic epitope for potent neutralizing antibodies. Current mRNA vaccines encode for the Spike protein, allowing the body to build antigen-specific antibodies. Assays measuring protective antibodies are essential to manage the COVID-19 pandemic and can be used as a platform for variant screening. RBD-foldon 2.2 is a novel antigen produced by fusing RBD with the trimerization domain Fibritin from Bacteriophage T4. Its amino acid sequence is based on the original …