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Full-Text Articles in Medicine and Health Sciences
Characterisation And Optimisation Of Gypsum Crystallization, Catherine H. Shannon
Characterisation And Optimisation Of Gypsum Crystallization, Catherine H. Shannon
Theses
Gypsum is produced as a by-product during the citric acid production process at ADM Ringaskiddy. The particle size and filterability of the gypsum has a critical bearing on the overall citric acid production rate. Prior to August 1996, research in the area of gypsum crystal optimisation at ADM had concentrated on the application of vortex mixing to perform the gypsum formation reaction. While the gypsum crystals produced with vortex mixing were found to be desirably clear of microcrystalline gypsum, the crystals were considerably smaller and more difficult to filter and wash. This research project sought to retain the advantages conferred …
Optimisation Studies In A Batch Pharmaceutical Company, Sarah Fitzgerald
Optimisation Studies In A Batch Pharmaceutical Company, Sarah Fitzgerald
Theses
This thesis outlines a collaborative project between industry and academia based on a short term research contract.
In the past in Eli Lilly, process optimisation in a multi-purpose, modular building had been mainly confined to equipment commissioning and new product development. It was necessary to embark upon an exercise to develop an optimisation programme m order to meet the increased requirements and demands of the building. Increased market demands, through the introduction of over-the-counter (OTC) drugs, and the demand for cycle time reduction through the expiry of existing patents, made the need for optimisation inevitable.
The purpose of this thesis …
Conjugated Bilirubin Measurement Re-Examined: A New 'Approach'., Aidan Kelleher
Conjugated Bilirubin Measurement Re-Examined: A New 'Approach'., Aidan Kelleher
Theses
Conjugated bilirubin is an important but difficult metabolite to measure accurately, elevated levels of conjugated bilirubin in the serum are indicative of obstructive jaundice and therefore can be used to discriminate this disorder from other forms of unconjugated hyper bilirubinaemia.
The Atomic Force Microscope In The Elucidation Of Leukocyte Abnormality, Derbrenn O'Connor
The Atomic Force Microscope In The Elucidation Of Leukocyte Abnormality, Derbrenn O'Connor
Theses
The aim of this project was to investigate the novel use of the atomic force microscope (AFM) as a technique in the elucidation of leukocyte abnormality. To this end, comparative AFM imaging and elasticity studies were performed on normal and myeloid leukaemic leukocytes.
Initially, an evaluation of techniques for the isolation of specific leukocyte (e.g. lymphocytes, granulocytes, etc.) populations from whole blood or leukocyte concentrates, was carried out. It was found that a silanised glass surface failed to select and immobilise a leukocyte population. However, centrifugation of whole blood in an Isopaque-ficoll gradient solution yielded a viable mixed leukocyte population …