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A Randomized Controlled Trial Of An Oral Probiotic To Reduce Antepartum Group B Streptococcus Colonization And Gastrointestinal Symptoms, Lisa Hanson, Leona Vandevusse, Marie Forgie, Emily Malloy, Maharaj Singh, Maryanne Scherer, Diana Kleber, Jonah Dixon, Andrew J. Hryckowian, Nasia Safdar
A Randomized Controlled Trial Of An Oral Probiotic To Reduce Antepartum Group B Streptococcus Colonization And Gastrointestinal Symptoms, Lisa Hanson, Leona Vandevusse, Marie Forgie, Emily Malloy, Maharaj Singh, Maryanne Scherer, Diana Kleber, Jonah Dixon, Andrew J. Hryckowian, Nasia Safdar
College of Nursing Faculty Research and Publications
BACKGROUND
Probiotics have been suggested as a strategy to reduce antenatal group B Streptococcus colonization. Although probiotics are known to improve gastrointestinal symptoms, this has not been studied during pregnancy.
OBJECTIVE
This study aimed to evaluate the efficacy of a probiotic to reduce: (1) standard-of-care antenatal group B Streptococcus colonization and colony counts and (2) gastrointestinal symptoms of pregnancy.
STUDY DESIGN
In a double-blind fashion, 109 healthy adult pregnant people were randomized to Florajen3 probiotic or placebo capsules once daily from 28 weeks’ gestation until labor onset. Baseline vaginal and rectal study swabs for group B Streptococcus colony-forming units and …