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Full-Text Articles in Medicine and Health Sciences
Efficacy Of The Biomaterials 3 Wt%-Nanostrontium-Hydroxyapatite-Enhanced Calcium Phosphate Cement (Nanosr-Cpc) And Nanosr-Cpc-Incorporated Simvastatin-Loaded Poly(Lactic-Co-Glycolic-Acid) Microspheres In Osteogenesis Improvement, Reza Masaeli, Tahereh S. Jafarzadeh Kashi, Rassoul Dinarvand, Vahid Rakhshan, Hossein Shahoon, Behzad Hooshmand, Fatemeh Mashhadi Abbas, Majid Raz, Alireza Rajabnejad, Hossein Eslami, Kimia Khoshroo, Mohammadreza Tahriri, Lobat Tayebi
Efficacy Of The Biomaterials 3 Wt%-Nanostrontium-Hydroxyapatite-Enhanced Calcium Phosphate Cement (Nanosr-Cpc) And Nanosr-Cpc-Incorporated Simvastatin-Loaded Poly(Lactic-Co-Glycolic-Acid) Microspheres In Osteogenesis Improvement, Reza Masaeli, Tahereh S. Jafarzadeh Kashi, Rassoul Dinarvand, Vahid Rakhshan, Hossein Shahoon, Behzad Hooshmand, Fatemeh Mashhadi Abbas, Majid Raz, Alireza Rajabnejad, Hossein Eslami, Kimia Khoshroo, Mohammadreza Tahriri, Lobat Tayebi
School of Dentistry Faculty Research and Publications
Aims
The purpose of this multi-phase explorative in vivo animal/surgical and in vitro multi-test experimental study was to (1) create a 3 wt%-nanostrontium hydroxyapatite-enhanced calcium phosphate cement (Sr-HA/CPC) for increasing bone formation and (2) creating a simvastatin-loaded poly(lactic-co-glycolic acid) (SIM-loaded PLGA) microspheres plus CPC composite (SIM-loaded PLGA + nanostrontium-CPC). The third goal was the extensive assessment of multiple in vitro and in vivo characteristics of the above experimental explorative products in vitro and in vivo (animal and surgical studies).
Methods and results pertaining to Sr-HA/CPC
Physical and chemical properties of the prepared Sr-HA/CPC were evaluated. MTT assay and …
Three-Dimensional Bioprinting Materials With Potential Application In Preprosthetic Surgery, Mina D. Fahmy, Hossein E. Jazayeri, Mehdi Razavi, Radi Masri, Lobat Tayebi
Three-Dimensional Bioprinting Materials With Potential Application In Preprosthetic Surgery, Mina D. Fahmy, Hossein E. Jazayeri, Mehdi Razavi, Radi Masri, Lobat Tayebi
School of Dentistry Faculty Research and Publications
Current methods in handling maxillofacial defects are not robust and are highly dependent on the surgeon’s skills and the inherent potential in the patients’ bodies for regenerating lost tissues. Employing custom-designed 3D printed scaffolds that securely and effectively reconstruct the defects by using tissue engineering and regenerative medicine techniques can revolutionize preprosthetic surgeries. Various polymers, ceramics, natural and synthetic bioplastics, proteins, biomolecules, living cells, and growth factors as well as their hybrid structures can be used in 3D printing of scaffolds, which are still under development by scientists. These scaffolds not only are beneficial due to their patient-specific design, but …