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Full-Text Articles in Medicine and Health Sciences
Mechanism Of Mechanical Vibration In Enhancing Orthodontic Retention- Analysis Of Global Gene Expression, Shuwei Wang
Mechanism Of Mechanical Vibration In Enhancing Orthodontic Retention- Analysis Of Global Gene Expression, Shuwei Wang
Master's Theses (2009 -)
Introduction: Low-magnitude, high-frequency (LMHF) mechanical vibration has been proposed as a possible adjunctive retention method after orthodontic treatment. In this study, we explored the mechanism of using LMHF vibration to improve bone formation during retention phase. We aimed to provide insight of global gene expression and cellular activities of PDL cells under tension, as well as identify novel biomarkers for induced osteogenesis by using LMHF mechanical vibration as adjunct tool in retention phase. Materials and Methods: Human PDL cells (hPDLCs) were seeded in 6-well FLEXCELL culture plates. The wells were assigned to four experimental groups as control, stretching (ST), vibration …
Application Of Mechanical Vibration To Enhance The Stability After Orthodontic Treatment - A Micro - Ct Study, Nicolas Branshaw
Application Of Mechanical Vibration To Enhance The Stability After Orthodontic Treatment - A Micro - Ct Study, Nicolas Branshaw
Master's Theses (2009 -)
Introduction: Mechanical vibration (MV) possesses anti-resorptive properties that can possibly enhance the stability of the dentition during retention, lessening the potential for relapse of teeth to their initial positions. In this project, we established a mouse model and investigated the effects of MV on bone modeling during orthodontic retention. Materials and Methods: Thirty-two 14-week-old inbred strain C57BL/6 male mice were randomly assigned into four groups: 1) Control (N=6); 2) Mechanical Vibration (MV) (N =6); 3) Orthodontic Retention (OR) (N=9); and 4) Orthodontic Retention and Mechanical Vibration (ORMV) (N=11). All mice in OR and ORMV groups received approximately 10g of orthodontic …
The Effect Of Mechanical Vibration On Human Pdl Cell Differentiation And Response To Inflammation, Megan Desroches
The Effect Of Mechanical Vibration On Human Pdl Cell Differentiation And Response To Inflammation, Megan Desroches
Master's Theses (2009 -)
Low magnitude mechanical vibration is a therapeutic adjunct being investigated to alter bone remodeling and inflammation in areas such as osteoporosis, bone fracture healing, and muscle soreness after exercise. In orthodontics a device named AcceleDent has been marketed that claims to increase the rate of tooth movement and decrease pain. However evidence for these claims is lacking. In this study we looked at two potential cellular mechanisms for these claims: periodontal ligament (PDL) cell differentiation and inflammation under an orthodontic model of strain (IL-1β). Increased PDL cell differentiation into osteogenic cells could be an avenue of increasing orthodontic tooth movement. …