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Local Control Of Pulmonary Resistance And Lung Compliance, Robert L. Coon

Dissertations (1934 -)

This study originated as a study of the effects of hypoxia and of various pharmacological agents on the pulmonary vasculature of the left lower lobe of the canine lung. Because the bronchomotor tone might also be affected, particularly by the pharmacological agents, it was decided as a secondary objective to also measure the effects of these agents on bronchomotor tone. It quickly became apparent that this was not as simple as it sounded. As no totally satisfactory method existed, a method of studying pulmonary mechanics in the left lower lobe in situ had to be developed. The effects of pump …