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La Salle University

Undergraduate Research

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Full-Text Articles in Medicine and Health Sciences

Targeting Tgf-Β During Epithelial-To-Mesenchymal Progression As An Effective Therapy Against Colorectal Cancer, Joyce Fan Apr 2024

Targeting Tgf-Β During Epithelial-To-Mesenchymal Progression As An Effective Therapy Against Colorectal Cancer, Joyce Fan

Undergraduate Research

Colorectal cancer is one of the most common cancers worldwide. Understanding the mechanisms of colorectal cancer progression is crucial for the development of effective therapeutics. Epithelial-to-mesenchymal transition is a hallmark feature of cancer and is defined as the loss of epithelial cell features, such as apical-basal polarity and high expression of cell adhesion molecules, and the development of mesenchymal features, such as lack of polarity and increased cell mobility. Epithelial-to-mesenchymal is essential for cell migration, proliferation, and tumor growth. Both the TGF-β and SMAD pathway are associated with colorectal cancer progression. TGF-β is crucial to the cellular mechanism of cell …


The Future Of Forensic Psychology, William J. Lasala May 2021

The Future Of Forensic Psychology, William J. Lasala

Undergraduate Research

Throughout my years at La Salle University as a dual Psychology and Criminal Justice major, I have had the opportunity to study and learn about a variety of different topics regarding these two fields. The specific field that I was drawn towards the most was the field of forensic psychology, which is why it is the topic of my research project. My project’s main goal is to ensure that forensic psychology, with some new improvements, continue to be a leading force in both the field of criminal justice and psychology. Specifically, my project focuses on the future of forensic psychology …


Time To Get In The Game: Opportunities For More Involvement In Sport-Related Concussion Management, Karle M. Linden, Ryan S. Husak, Evelyn Klein, Meredith Kneavel Apr 2021

Time To Get In The Game: Opportunities For More Involvement In Sport-Related Concussion Management, Karle M. Linden, Ryan S. Husak, Evelyn Klein, Meredith Kneavel

Undergraduate Research

Many college athletes who have a sport-related concussion experience changes in cognitive-communication abilities. Unfortunately, nearly half of all sport-related concussions go unreported. Information on why collegiate athletes report or conceal their symptoms is important for improving reporting rates and increasing athletes’ access to services for cognitive-communication impairments. This study examined whether changes in cognitive-communication abilities affected college athlete’s intentions to report a sport-related concussion. Findings showed that approximately two-thirds of the college student-athletes who participated in the research were unlikely to report that they had a sport-related head injury. The study found that participants’ concerns for cognitive-communication deficits differentiated student-athletes …


Readability Levels Of Speech-Language Pathology And Audiology Online Patient Education Materials In English And Spanish, Astrid Olivera, Sarah Gallagher, Dana Bitetti Apr 2019

Readability Levels Of Speech-Language Pathology And Audiology Online Patient Education Materials In English And Spanish, Astrid Olivera, Sarah Gallagher, Dana Bitetti

Undergraduate Research

Clinicians have role in educating patients and their families about communication disorders. Therefore patient materials must have an appropriate level of readability. Studies are needed that investigate the readability of online patient education materials. This study investigated 30 online patient handouts in English and Spanish using several readability indices. The results indicated that few handouts met the recommended readability levels.


Being "With Women, For A Lifetime": The Current State Of Nurse-Midwifery Practice In The United States, Michal Koren May 2017

Being "With Women, For A Lifetime": The Current State Of Nurse-Midwifery Practice In The United States, Michal Koren

Undergraduate Research

The purpose of this research project is to explore the evolution of midwifery care from its earliest beginnings steeped within societal structures and birthing customs to its contemporary practices filled with professional regulations and competing technologies. Focused interest will be given to: 1) identifying the core values and basic principles of midwifery that have endured over time, and 2) ascertaining the significant changes in educational regulations and clinical competencies that influence midwifery practice in contemporary times.


Sexual Assault On College Campuses: An Epidemic And An Alternative Approach, Mark N. Devone Apr 2017

Sexual Assault On College Campuses: An Epidemic And An Alternative Approach, Mark N. Devone

Undergraduate Research

Sexual assault is a major problem that is occurring at staggering rates on college campuses nationwide. Sexual Assault on College Campuses: An Epidemic and An Alternative Approach takes an in depth look at the problem at hand and discusses how the current ways of handling sexual assault cases and their faults. An alternative approach is introduced as a possible way to help fix the current sexual assault problem. The approach is Restorative Justice, which focuses on the rehabilitation of the offender and the healing of the victim through reconciliation techniques that include the victim, offender, and the community.


Code Mixing In Narratives Of Spanish-English Dual Language Learners, Janine Peca Apr 2017

Code Mixing In Narratives Of Spanish-English Dual Language Learners, Janine Peca

Undergraduate Research

As the U.S. diversifies, the number of Spanish-English dual language learners (DLLs) has grown significantly and is projected to continue to do so through 2060 (Colby & Ortman, 2015). Although research has shown that DLLs implement strategies, like code mixing, to compensate for varying language proficiencies (Vu, Bailey, & Howes, 2010), what elements of code mixing are typical has not been widely researched. This study aims to add to the body of work on typical development of DLL children by examining code mixing in narratives of 212 Spanish-English dual language learners at the beginning of preschool, to determine if differences …


Mindsets, Kelly White, Jennifer Kleinow Apr 2016

Mindsets, Kelly White, Jennifer Kleinow

Undergraduate Research

The concept of mindsets was developed by Carol Dweck, a Stanford University psychologist. Her vision was to help children and adults understand that they do not have a fixed amount of intelligence or a fixed amount of talent. Dweck implies that we are not born with a gene that says this is the only amount of talent and intelligence that we will ever have in our lifetime. Our talents and intelligence can be manipulated through hard work and practice. Dweck has devised two terms that are central to her mindsets concept. The first is a fixed mindset which is the …


Students’ Perceptions Of Female Faculty Members Based On Vocal Characteristics, Molly M. Kitchell, Cesar E. Ruiz Slp.D., Ccc/Slp., Bcs-S Apr 2015

Students’ Perceptions Of Female Faculty Members Based On Vocal Characteristics, Molly M. Kitchell, Cesar E. Ruiz Slp.D., Ccc/Slp., Bcs-S

Undergraduate Research

This study examines the relationship between the acoustic properties of female faculty members’ voices and the perception of the female faculty members age and personality characteristics by undergraduate students. A standardized acoustic analysis using the Multidimensional Voice Program (MDVP) and the RealPitch program was performed to determine the participating faculty members’ fundamental frequency (habitual and conversation), vocal jitter, and vocal shimmer. Faculty members were then recorded reading a brief preselected passage. Student participants listened to the recorded audio samples and completed a survey regarding the faculty members’ ages and personality characteristics. A Pearson product-moment correlation (Pearson r) analysis completed in …


Examining Phage Infection Utilizing Mycobacterium Smegmatis, Tanya L. Riddick Apr 2015

Examining Phage Infection Utilizing Mycobacterium Smegmatis, Tanya L. Riddick

Undergraduate Research

Bacteriophages, also known as phages, are viruses that are ubiquitous and survive and replicate within the host of the bacterial cell, Mycobacterium smegmatis. They are considered one of the most abundant organisms on earth (1031). Structurally, they are 100-200nm in size and consist of a protein encapsulated head that contains DNA or RNA, a tail sheath and tail fibers. This research consisted of examining phage infection, by re-isolating a novel phage, Tango. Tango was originally isolated genetically in 2013 by a previous ISBT student, Anna Maccarrone. The phage was sent to genetic sequencing but two phages were discovered, …


Parental Knowledge Of Shaken Baby Syndrome: Effects Of A High Risk Parent Teaching Program On Incidence Of Abusive Head Trauma, Mujeebat Suleiman Apr 2015

Parental Knowledge Of Shaken Baby Syndrome: Effects Of A High Risk Parent Teaching Program On Incidence Of Abusive Head Trauma, Mujeebat Suleiman

Undergraduate Research

The purpose of this research is to determine if parents and caregivers are educated about SBS, the incidence of SBS decreases. The subjects of this study are parents of newborns born at Pennsylvania Hospital. The experimental group will consist of 50 parents who will receive supplemental information in regards to preventing Shaken Baby Syndrome. The comparison group will consist of 50 parents who will receive no further education from the one received prior to discharge of the hospital. After the study is completed, the experimental group will be compared to the comparison group on the decrease incidence of SBS they …


Healing Through Art: An Examination Of Northern Ireland’S ‘Troubles’, Alexis Dunn Apr 2015

Healing Through Art: An Examination Of Northern Ireland’S ‘Troubles’, Alexis Dunn

Undergraduate Research

No abstract provided.