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Grand Valley State University

Masters Theses

Theses/Dissertations

Adrenergic pig

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Vascular Effects Of Dietary Supplement Bmpea On Mesenteric Porcine Vasculature, Clifford Cooper Apr 2017

Vascular Effects Of Dietary Supplement Bmpea On Mesenteric Porcine Vasculature, Clifford Cooper

Masters Theses

β-methylphenylethylamine (BMPEA) was first synthesized in the 1930’s as a potential stimulant and amphetamine replacement. It was expected to act as an indirect sympathomimetic agent that binds to peripheral α- and β- adrenergic receptors to control vascular responses in peripheral sites. The effects of BMPEA were never studied in humans, but due to its structural similarity to amphetamines as well as the effects noticed in animal studies in the 1920’s and 1930’s, BMPEA was assumed to work as a vasoconstrictor. In the current study, porcine mesenteric arteries were used as a model following confirmation of arterial viability with the known …