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The Effect Of Chewable Chitosan On Phosphate Levels In Serum And Saliva In Hemodialysis Pediatric Patients, Mahy Salem, Mervat Fawzy, Mohamed Mostafa, Moftah Rabea

Al-Azhar Journal of Dentistry

Purpose: To evaluate the effect of a salivary phosphate binder “Chitosan” in a chewable form on serum and salivary levels of phosphate, calcium and urea in a group of hyperphosphatemic, hemodialysis pediatric patients suffering from end stage renal disease. Subjects and Methods: The study comprised 30 children on hemodialysis; (14 males and 16 females), aging 7-16 years, selected from the hemodialysis units of Al-Azhar University Hospitals. All the children chewed chitosan loaded chewing gum for one hour, twice daily, during the fasting hours between meals throughout the trial period (3 months), while maintained on oral phosphate binders. Results: There was …