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Evaluation Of 3d Computer-Assisted Patient’S Specific Scaffold Seeded With Autogenous Stem Cells And Platelet-Rich Fibrin In Alveolar Cleft Repair, Ahmad Abd El Azeem, Hatem Al-Ahmady, Mostapha Abdul Rahman

Al-Azhar Journal of Dentistry

Purpose: Evaluation of the treatment outcome of using patient-specific implantable scaffolds seeded with autogenous bone marrow mononuclear cell layer containing stem cells and platelet-rich fibrin in the treatment of alveolar cleft defect. Materials and methods: 12 alveolar cleft defects were divided into 2 groups; group A, six alveolar defects were treated using 3D printed patient’s specific implantable PLLA scaffolds seeded with autogenous bone marrow mononuclear cell layer containing stem cells and platelet-rich fibrin. Group B, six alveolar defects were treated with standard anterior iliac crest cortico-cancellous alveolar bone grafting procedures. Clinical and radiographic assessments were done to compare between two …