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Full-Text Articles in Medicine and Health Sciences
Comparison Of In Vitro Biocompatibility Of Nanobone(®) And Biooss(®) For Human Osteoblasts, Qin Liu, Timothy Douglas, Christiane Zamponi, Stephan Becker, Eugene Sherry, Sureshan Sivananthan, Frauke Warnke, Jörg Wiltfang, Patrick Warnke
Comparison Of In Vitro Biocompatibility Of Nanobone(®) And Biooss(®) For Human Osteoblasts, Qin Liu, Timothy Douglas, Christiane Zamponi, Stephan Becker, Eugene Sherry, Sureshan Sivananthan, Frauke Warnke, Jörg Wiltfang, Patrick Warnke
Qin Liu
Introduction:Scaffolds for bone tissue engineering seeded with the patient's own cells might be used as a preferable method to repair bone defects in the future. With the emerging new technologies of nanostructure design, new synthetic biomaterials are appearing on the market. Such scaffolds must be tested in vitro for their biocompatibility before clinical application. However, the choice between a natural or a synthetic biomaterial might be challenging for the doctor and the patient. In this study, we compared the biocompatibility of a synthetic bone substitute, NanoBone®, to the widely used natural bovine bone replacement material BioOss®.Material and methods: The in …
Ceramic Scaffolds Produced By Computer-Assisted 3d Printing And Sintering: Characterization And Biocompatibility Investigations, Patrick Warnke, Hermann Seitz, Stephan Becker, Sureshan Sivananthan, Eugene Sherry, Qin Liu, Jorge Wiltfang, Timothy Douglas
Ceramic Scaffolds Produced By Computer-Assisted 3d Printing And Sintering: Characterization And Biocompatibility Investigations, Patrick Warnke, Hermann Seitz, Stephan Becker, Sureshan Sivananthan, Eugene Sherry, Qin Liu, Jorge Wiltfang, Timothy Douglas
Qin Liu
Hydroxyapatite (HAP) and tricalcium phosphate (TCP) are two very common ceramic materials for bone replacement. However, in general HAP and TCP scaffolds are not tailored to the exact dimensions of the defect site and are mainly used as granules or beads. Some scaffolds are available as ordinary blocks, but cannot be customized for individual perfect fit. Using computer-assisted 3D printing, an emerging rapid prototyping technique, individual three-dimensional ceramic scaffolds can be built up from TCP or HAP powder layer by layer with subsequent sintering. These scaffolds have precise dimensions and highly defined and regular internal characteristics such as pore size. …