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Full-Text Articles in Medicine and Health Sciences

Selective Suppression Of Cervical Cancer Hela Cells By 2-O-Beta-D-Glucopyranosyl-L-Ascorbic Acid Isolated From The Fruit Of Lycium Barbarum L., Zhiping Zhang, Xiaoming Liu, Tao Wu, Junhong Liu, Xu Zhang, Xueyun Yang, Michael Goodheart, John Engelhardt, Yujiong Wang May 2013

Selective Suppression Of Cervical Cancer Hela Cells By 2-O-Beta-D-Glucopyranosyl-L-Ascorbic Acid Isolated From The Fruit Of Lycium Barbarum L., Zhiping Zhang, Xiaoming Liu, Tao Wu, Junhong Liu, Xu Zhang, Xueyun Yang, Michael Goodheart, John Engelhardt, Yujiong Wang

Koen De Geest

No abstract provided.


The Role Of Lef1 In Endometrial Gland Formation And Carcinogenesis, Dawne Shelton, Hubert Fornalik, Traci Neff, Soo Park, David Bender, Koen Degeest, Xiaoming Liu, Weiliang Xie, David Meyerholz, John Engelhardt, Michael Goodheart May 2013

The Role Of Lef1 In Endometrial Gland Formation And Carcinogenesis, Dawne Shelton, Hubert Fornalik, Traci Neff, Soo Park, David Bender, Koen Degeest, Xiaoming Liu, Weiliang Xie, David Meyerholz, John Engelhardt, Michael Goodheart

Koen De Geest

No abstract provided.


Metabolism Gone Awry: How Ovarian Cancer's Metabolism Differs From The Normal Ovary, B. Zand, J. Bottsford-Miller, A. Nick, W. Hu, R. Stone, Koen De Geest, S. Lutgendorf, A. Sood Apr 2013

Metabolism Gone Awry: How Ovarian Cancer's Metabolism Differs From The Normal Ovary, B. Zand, J. Bottsford-Miller, A. Nick, W. Hu, R. Stone, Koen De Geest, S. Lutgendorf, A. Sood

Koen De Geest

No abstract provided.


Salvage Mitomycin/5-Fluorouracil After Platinum-Based Therapy For Women With Advanced Ovarian Cancer And Related Gynecologic Malignancies., L. Massad, E. Wagley, L. Winkelman, S. Lincoln, E. Yordan, Koen De Geest, G. Wilbanks Apr 2013

Salvage Mitomycin/5-Fluorouracil After Platinum-Based Therapy For Women With Advanced Ovarian Cancer And Related Gynecologic Malignancies., L. Massad, E. Wagley, L. Winkelman, S. Lincoln, E. Yordan, Koen De Geest, G. Wilbanks

Koen De Geest

No abstract provided.


Effect Of Interleukin-8 Gene Silencing With Liposome-Encapsulated Small Interfering Rna On Ovarian Cancer Cell Growth, William Merritt, Yvonne Lin, Whitney Spannuth, Mavis Fletcher, Aparna Kamat, Liz Han, Charles Landen, Nicholas Jennings, Koen De Geest, Robert Langley, Gabriel Villares, Angela Sanguino, Susan Lutgendorf, Gabriel Lopez-Berestein, Menashe Bar-Eli, Anil Sood Apr 2013

Effect Of Interleukin-8 Gene Silencing With Liposome-Encapsulated Small Interfering Rna On Ovarian Cancer Cell Growth, William Merritt, Yvonne Lin, Whitney Spannuth, Mavis Fletcher, Aparna Kamat, Liz Han, Charles Landen, Nicholas Jennings, Koen De Geest, Robert Langley, Gabriel Villares, Angela Sanguino, Susan Lutgendorf, Gabriel Lopez-Berestein, Menashe Bar-Eli, Anil Sood

Koen De Geest

No abstract provided.


A Gynecologic Oncology Group Phase Ii Trial Of The Protein Kinase C-Beta Inhibitor, Enzastaurin And Evaluation Of Markers With Potential Predictive And Prognostic Value In Persistent Or Recurrent Epithelial Ovarian And Primary Peritoneal Malignancies, Lydia Usha, Michael Sill, Kathleen Darcy, Doris Benbrook, Jean Hurteau, David Michelin, Robert Mannel, Parviz Hanjani, Koen De Geest, Andrew Godwin Apr 2013

A Gynecologic Oncology Group Phase Ii Trial Of The Protein Kinase C-Beta Inhibitor, Enzastaurin And Evaluation Of Markers With Potential Predictive And Prognostic Value In Persistent Or Recurrent Epithelial Ovarian And Primary Peritoneal Malignancies, Lydia Usha, Michael Sill, Kathleen Darcy, Doris Benbrook, Jean Hurteau, David Michelin, Robert Mannel, Parviz Hanjani, Koen De Geest, Andrew Godwin

Koen De Geest

No abstract provided.


Endocervical Prostaglandin-E2 Gel For Preinduction Cervical Softening, M. Thiery, J. Decoster, W. Parewijck, M. Noah, R. Derom, H. Vankets, P. Defoort, W. Aertsens, G. Debruyne, Koen De Geest, F. Vandekerckhove Apr 2013

Endocervical Prostaglandin-E2 Gel For Preinduction Cervical Softening, M. Thiery, J. Decoster, W. Parewijck, M. Noah, R. Derom, H. Vankets, P. Defoort, W. Aertsens, G. Debruyne, Koen De Geest, F. Vandekerckhove

Koen De Geest

No abstract provided.


A Phase I Trial Of Tailored Radiation Therapy With Concomitant Cetuximab And Cisplatin In The Treatment Of Patients With Cervical Cancer: A Gynecologic Oncology Group Study, Kathleen Moore, Michael Sill, David Miller, Carolyn Mccourt, Koen De Geest, Peter Rose, Higinia Cardenes, Robert Mannel, John Farley, Russell Schilder, Paula Fracasso Apr 2013

A Phase I Trial Of Tailored Radiation Therapy With Concomitant Cetuximab And Cisplatin In The Treatment Of Patients With Cervical Cancer: A Gynecologic Oncology Group Study, Kathleen Moore, Michael Sill, David Miller, Carolyn Mccourt, Koen De Geest, Peter Rose, Higinia Cardenes, Robert Mannel, John Farley, Russell Schilder, Paula Fracasso

Koen De Geest

No abstract provided.


Differential Response Of Cervical Intraepithelial And Cervical-Carcinoma Cell-Lines To Transforming Growth-Factor-Beta-1, Koen De Geest, C. Bergman, M. Turyk, B. Frank, G. Wilbanks Apr 2013

Differential Response Of Cervical Intraepithelial And Cervical-Carcinoma Cell-Lines To Transforming Growth-Factor-Beta-1, Koen De Geest, C. Bergman, M. Turyk, B. Frank, G. Wilbanks

Koen De Geest

No abstract provided.


Patient-Reported Peripheral Neuropathy Of Doxorubicin And Cisplatin With And Without Paclitaxel In The Treatment Of Advanced Endometrial Cancer: Results From Gog 184, David Cella, Helen Huang, Howard Homesley, Anthony Montag, Ritu Salani, Koen De Geest, Roger Lee, Nick Spirtos Apr 2013

Patient-Reported Peripheral Neuropathy Of Doxorubicin And Cisplatin With And Without Paclitaxel In The Treatment Of Advanced Endometrial Cancer: Results From Gog 184, David Cella, Helen Huang, Howard Homesley, Anthony Montag, Ritu Salani, Koen De Geest, Roger Lee, Nick Spirtos

Koen De Geest

No abstract provided.


Epigenetic Regulation Of Maspin Expression In Human Ovarian Carcinoma Cells, Stephen Rose, Matthew Fitzgerald, Natalie White, Michael Hitchler, Bernard Futscher, Koen De Geest, Frederick Domann Apr 2013

Epigenetic Regulation Of Maspin Expression In Human Ovarian Carcinoma Cells, Stephen Rose, Matthew Fitzgerald, Natalie White, Michael Hitchler, Bernard Futscher, Koen De Geest, Frederick Domann

Koen De Geest

No abstract provided.


Social Support, Psychological Distress, And Natural Killer Cell Activity In Ovarian Cancer, S. Lutgendorf, A. Sood, B. Anderson, S. Mcginn, H. Maiseri, M. Dao, J. Sorosky, Koen De Geest, J. Ritchie, D. Lubaroff Apr 2013

Social Support, Psychological Distress, And Natural Killer Cell Activity In Ovarian Cancer, S. Lutgendorf, A. Sood, B. Anderson, S. Mcginn, H. Maiseri, M. Dao, J. Sorosky, Koen De Geest, J. Ritchie, D. Lubaroff

Koen De Geest

PURPOSE: Psychosocial stress has been related to impaired immunity in cancer patients. However, the extent to which these relationships exist in immune cells in the tumor microenvironment in humans has not been explored. We examined relationships among distress, social support, and natural killer (NK) cell activity in ovarian cancer patients in peripheral-blood mononuclear cells (PBMC), ascitic fluid, and tumor-infiltrating lymphocytes (TIL). PATIENTS AND METHODS: Patients awaiting surgery for a pelvic mass suspected of being ovarian cancer completed psychological questionnaires and gave a presurgical sample of peripheral blood. Samples of tumor and ascites were taken during surgery, lymphocytes were then isolated, …


Bevacizumab Shows Activity In Treating Recurrent Sex Cord-Stromal Ovarian Tumors: Results Of A Phase Ii Trial Of The Gynecologic Oncology Group, J. Brown, W. Brady, J. Schink, L. Van Le, M. Leitao, S. Yamada, Koen De Geest, D. Gershenson Apr 2013

Bevacizumab Shows Activity In Treating Recurrent Sex Cord-Stromal Ovarian Tumors: Results Of A Phase Ii Trial Of The Gynecologic Oncology Group, J. Brown, W. Brady, J. Schink, L. Van Le, M. Leitao, S. Yamada, Koen De Geest, D. Gershenson

Koen De Geest

No abstract provided.


An Alternative Zmiz1 Promoter Exhibits Higher Gene Expression In Epithelial Ovarian Cancer That Is P53-Independent, N. Nadkarni, L. Rogers, M. Samuelson, T. Neff, D. Bender, A. Ahmed, Koen De Geest, A. Button, A. Dupuy, Michael Goodheart Apr 2013

An Alternative Zmiz1 Promoter Exhibits Higher Gene Expression In Epithelial Ovarian Cancer That Is P53-Independent, N. Nadkarni, L. Rogers, M. Samuelson, T. Neff, D. Bender, A. Ahmed, Koen De Geest, A. Button, A. Dupuy, Michael Goodheart

Koen De Geest

No abstract provided.


Hla Class I Antigen Processing Machinery Component Expression And Intratumoral T-Cell Infiltrate As Independent Prognostic Markers In Ovarian Carcinoma, Liz Han, Mavis Fletcher, Diana Urbauer, Peter Mueller, Charles Landen, Aparna Kamat, Yvonne Lin, William Merritt, Whitney Spannuth, Michael Deavers, Koen De Geest, David Gershenson, Susan Lutgendorf, Soldano Ferrone, Anil Sood Apr 2013

Hla Class I Antigen Processing Machinery Component Expression And Intratumoral T-Cell Infiltrate As Independent Prognostic Markers In Ovarian Carcinoma, Liz Han, Mavis Fletcher, Diana Urbauer, Peter Mueller, Charles Landen, Aparna Kamat, Yvonne Lin, William Merritt, Whitney Spannuth, Michael Deavers, Koen De Geest, David Gershenson, Susan Lutgendorf, Soldano Ferrone, Anil Sood

Koen De Geest

No abstract provided.


Evaluation Of New Platinum-Based Treatment Regimens In Advanced-Stage Ovarian Cancer: A Phase Iii Trial Of The Gynecologic Cancer Intergroup, Michael Bookman, Mark Brady, William Mcguire, Peter Harper, David Alberts, Michael Friedlander, Nicoletta Colombo, Jeffrey Fowler, Peter Argenta, Koen De Geest, David Mutch, Robert Burger, Ann Marie Swart, Edward Trimble, Chrisann Accario-Winslow, Lawrence Roth Apr 2013

Evaluation Of New Platinum-Based Treatment Regimens In Advanced-Stage Ovarian Cancer: A Phase Iii Trial Of The Gynecologic Cancer Intergroup, Michael Bookman, Mark Brady, William Mcguire, Peter Harper, David Alberts, Michael Friedlander, Nicoletta Colombo, Jeffrey Fowler, Peter Argenta, Koen De Geest, David Mutch, Robert Burger, Ann Marie Swart, Edward Trimble, Chrisann Accario-Winslow, Lawrence Roth

Koen De Geest

No abstract provided.


A Phase I Study With An Expanded Cohort To Assess The Feasibility Of Intraperitoneal Carboplatin And Intravenous Paclitaxel In Untreated Ovarian, Fallopian Tube, And Primary Peritoneal Carcinoma: A Gynecologic Oncology Group Study, M. Morgan, M. Sill, K. Fujiwara, B. Geer, S. Rubin, Koen De Geest, S. Yamada, S. Waggoner, R. Coleman, J. Walker, R. Mannel Apr 2013

A Phase I Study With An Expanded Cohort To Assess The Feasibility Of Intraperitoneal Carboplatin And Intravenous Paclitaxel In Untreated Ovarian, Fallopian Tube, And Primary Peritoneal Carcinoma: A Gynecologic Oncology Group Study, M. Morgan, M. Sill, K. Fujiwara, B. Geer, S. Rubin, Koen De Geest, S. Yamada, S. Waggoner, R. Coleman, J. Walker, R. Mannel

Koen De Geest

No abstract provided.


Serum Biomarker Panels For The Discrimination Of Benign From Malignant Cases In Patients With An Adnexal Mass, Brian Nolen, Liudmila Velikokhatnaya, Adele Marrangoni, Koen De Geest, Aleksey Lomakin, Robert Bast, Anna Lokshin Apr 2013

Serum Biomarker Panels For The Discrimination Of Benign From Malignant Cases In Patients With An Adnexal Mass, Brian Nolen, Liudmila Velikokhatnaya, Adele Marrangoni, Koen De Geest, Aleksey Lomakin, Robert Bast, Anna Lokshin

Koen De Geest

No abstract provided.


Lymphatic Mapping And Sentinel Lymph Node Biopsy In Women With Squamous Cell Carcinoma Of The Vulva: A Gynecologic Oncology Group Study, Charles Levenback, Shamshad Ali, Robert Coleman, Michael Gold, Jeffrey Fowler, Patricia Judson, Maria Bell, Koen De Geest, Nick Spirtos, Ronald Potkul, Mario Leitao, Jamie Bakkum-Gamez, Emma Rossi, Samuel Lentz, James Burke, Linda Van Le, Cornelia Trimble Apr 2013

Lymphatic Mapping And Sentinel Lymph Node Biopsy In Women With Squamous Cell Carcinoma Of The Vulva: A Gynecologic Oncology Group Study, Charles Levenback, Shamshad Ali, Robert Coleman, Michael Gold, Jeffrey Fowler, Patricia Judson, Maria Bell, Koen De Geest, Nick Spirtos, Ronald Potkul, Mario Leitao, Jamie Bakkum-Gamez, Emma Rossi, Samuel Lentz, James Burke, Linda Van Le, Cornelia Trimble

Koen De Geest

No abstract provided.


Scalene Lymph-Node Biopsy In The Preoperative Evaluation Of Patients With Recurrent Cervical-Cancer, A. Manetta, E. Podczaski, J. Larson, Koen De Geest, R. Mortel Apr 2013

Scalene Lymph-Node Biopsy In The Preoperative Evaluation Of Patients With Recurrent Cervical-Cancer, A. Manetta, E. Podczaski, J. Larson, Koen De Geest, R. Mortel

Koen De Geest

No abstract provided.


A Gynecologic Oncology Group Phase Ii Trial Of The Protein Kinase C-Beta Inhibitor Enzastaurin And Evaluation Of Markers With Potential Predictive And Prognostic Value In Persistent Or Recurrent Epithelial Ovarian And Primary Peritoneal Malignancies, L. Usha, M. Sill, K. Darcy, D. Benbrook, J. Hurteau, D. Michelin, R. Mannel, P. Hanjani, Koen De Geest, A. Godwin Apr 2013

A Gynecologic Oncology Group Phase Ii Trial Of The Protein Kinase C-Beta Inhibitor Enzastaurin And Evaluation Of Markers With Potential Predictive And Prognostic Value In Persistent Or Recurrent Epithelial Ovarian And Primary Peritoneal Malignancies, L. Usha, M. Sill, K. Darcy, D. Benbrook, J. Hurteau, D. Michelin, R. Mannel, P. Hanjani, Koen De Geest, A. Godwin

Koen De Geest

No abstract provided.


A Phase Ii Study Of A Urokinase-Derived Peptide (A6) In The Treatment Of Persistent Or Recurrent Epithelial Ovarian, Fallopian Tube, Or Primary Peritoneal Carcinoma: A Gynecologic Oncology Group Study, Michael Gold, William Brady, Heather Lankes, Peter Rose, Joseph Kelley, Koen De Geest, Marta Crispens, Kimberly Resnick, Stephen Howell Apr 2013

A Phase Ii Study Of A Urokinase-Derived Peptide (A6) In The Treatment Of Persistent Or Recurrent Epithelial Ovarian, Fallopian Tube, Or Primary Peritoneal Carcinoma: A Gynecologic Oncology Group Study, Michael Gold, William Brady, Heather Lankes, Peter Rose, Joseph Kelley, Koen De Geest, Marta Crispens, Kimberly Resnick, Stephen Howell

Koen De Geest

No abstract provided.


Smoking, Obesity, And Survival In Squamous-Cell Carcinoma Of The Vulva, C. Kirschner, E. Yordan, Koen Degeest, G. Wilbanks Apr 2013

Smoking, Obesity, And Survival In Squamous-Cell Carcinoma Of The Vulva, C. Kirschner, E. Yordan, Koen Degeest, G. Wilbanks

Koen De Geest

No abstract provided.


True Blood: Platelets As A Biomarker Of Ovarian Cancer Recurrence, J. Bottsford-Miller, S. Lutgendorf, C. Pecot, R. Stone, A. Nick, K. Matsuo, E. King, K. Ring, Koen De Geest, A. Sood Apr 2013

True Blood: Platelets As A Biomarker Of Ovarian Cancer Recurrence, J. Bottsford-Miller, S. Lutgendorf, C. Pecot, R. Stone, A. Nick, K. Matsuo, E. King, K. Ring, Koen De Geest, A. Sood

Koen De Geest

No abstract provided.


Growth And Differentiation Of Human Papillomavirus Type-31b Positive Human Cervical Cell-Lines, Koen De Geest, M. Turyk, M. Hosken, J. Hudson, L. Laimins, G. Wilbanks Apr 2013

Growth And Differentiation Of Human Papillomavirus Type-31b Positive Human Cervical Cell-Lines, Koen De Geest, M. Turyk, M. Hosken, J. Hudson, L. Laimins, G. Wilbanks

Koen De Geest

No abstract provided.


Docetaxel Plus Trabectedin Appears Active In Recurrent Or Persistent Ovarian And Primary Peritoneal Cancer After Up To Three Prior Regimens: A Phase Ii Study Of The Gynecologic Oncology Group, Bradley Monk, Michael Sill, Parviz Hanjani, Robert Edwards, Jacob Rotmensch, Koen De Geest, Albert Bonebrake, Joan Walker Apr 2013

Docetaxel Plus Trabectedin Appears Active In Recurrent Or Persistent Ovarian And Primary Peritoneal Cancer After Up To Three Prior Regimens: A Phase Ii Study Of The Gynecologic Oncology Group, Bradley Monk, Michael Sill, Parviz Hanjani, Robert Edwards, Jacob Rotmensch, Koen De Geest, Albert Bonebrake, Joan Walker

Koen De Geest

No abstract provided.


The Role Of Angiogenic Markers In Stage Iii And Iv Ovarian Cancer And Their Association With Mutations Of The P53 Gene, N. Nadkarni, D. Bender, T. Buekers, Koen De Geest, M. Zimmerman, Michael Goodheart Apr 2013

The Role Of Angiogenic Markers In Stage Iii And Iv Ovarian Cancer And Their Association With Mutations Of The P53 Gene, N. Nadkarni, D. Bender, T. Buekers, Koen De Geest, M. Zimmerman, Michael Goodheart

Koen De Geest

No abstract provided.


Multimodality Therapy For Carcinoma Of The Bartholin Gland, L. Massad, Koen De Geest Apr 2013

Multimodality Therapy For Carcinoma Of The Bartholin Gland, L. Massad, Koen De Geest

Koen De Geest

No abstract provided.


Adenosarcoma In A Patient With Vaginal Endometriosis, J. Anderson, K. Behbakht, Koen De Geest, P. Bitterman Apr 2013

Adenosarcoma In A Patient With Vaginal Endometriosis, J. Anderson, K. Behbakht, Koen De Geest, P. Bitterman

Koen De Geest

No abstract provided.


Evaluation Of Ep300, A Histone Acetyletransferase, In Patients With Epithelial Ovarian Carcinoma, M. Strigenz, N. Nadkarni, Y. Chin, T. Neff, S. Park, D. Bender, A. Ahmed, Koen De Geest, Michael Goodheart Apr 2013

Evaluation Of Ep300, A Histone Acetyletransferase, In Patients With Epithelial Ovarian Carcinoma, M. Strigenz, N. Nadkarni, Y. Chin, T. Neff, S. Park, D. Bender, A. Ahmed, Koen De Geest, Michael Goodheart

Koen De Geest

No abstract provided.