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Assessment Of Ovarian Reserve With Anti-Mullerian Hormone: A Comparison Of The Predictive Value Of Anti-Mullerian Hormone, Follicle-Stimulating Hormone, Inhibin B, And Age, R. Riggs, Eyup Duran, M. Baker, T. Kimble, E. Hobeika, L. Yin, L. Matos-Bodden, B. Leader, L. Stadtmauer

Eyup Hakan Duran

OBJECTIVE: The objective of this study was to evaluate basal anti-Mullerian hormone as a marker for ovarian responsiveness to fertility treatment. STUDY DESIGN: Frozen basal menstrual cycle day 3 serum samples were evaluated retrospectively for anti-Mullerian hormone, inhibin B, and follicle-stimulating hormone levels in 123 in vitro fertilization cycles (93 patients) and compared with in vitro fertilization records. RESULTS: Anti-Mullerian hormone values correlated the best with the number of retrieved oocytes (r = 0.539; P .05), luteinizing hormone (P > .05), and estradiol (r = -0.190; P .05), luteinizing hormone (P > .05), and estradiol (r = -0.190; P .05). Similarly, for …

Cumulative Exposure To High Estradiol Levels During The Follicular Phase Of Ivf Cycles Negatively Affects Implantation., Murat Arslan, Silvina Bocca, Ebru Arslan, E. Duran, Laurel Stadtmauer, Sergio Oehninger

Eyup Hakan Duran

PURPOSE: To investigate the effect of the cumulative exposure to estradiol (E(2)) during the follicular phase on IVF outcome.

METHODS: Patients were stimulated with recombinant FSH after GnRH agonist suppression and had a day 3-embryo transfer. Estrogen exposure was determined as the area under the curve (AUC) for serum E(2) levels measured from the first day of stimulation through the day after hCG administration.

RESULTS: E(2) AUC thresholds for 10th and 90th percentiles were 4704 pg/ml and 16338 pg/ml, respectively. The pregnancy and implantation rates were highest in the 10th-90th percentile group, and were statistically higher in this group than …