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Articles 1 - 8 of 8
Full-Text Articles in Medicine and Health Sciences
The Effect Of Distal Femoral Resection On Fixed Flexion Deformity In Total Knee Arthroplasty, David Liu, James Reidy, Elaine Beller
The Effect Of Distal Femoral Resection On Fixed Flexion Deformity In Total Knee Arthroplasty, David Liu, James Reidy, Elaine Beller
Elaine Beller
This study aims to quantify the relationship between distal femoral bone resection and correction of fixed flexion in total knee arthroplasty (TKA). Two previous studies have reported conflicting results. Spacers attached to the trial femoral component simulated additional distal femoral resection and the degree of knee flexion was recorded using computer navigation. The 2-mm augment produced an average of 3.37° of flexion deformity, 4-mm augment 6.68°, and 6-mm augment 11.38°. The amount of pre-resection flexion contracture significantly impacted on the effect of each augment. From our results, an additional 3.55 mm of distal femoral bone resection is required to correct …
Prevalence And Risk Factors For Low Habitual Walking Speed In Nursing Home Residents: An Observational Study, Justin Keogh, Hugh Senior, Elaine Beller, Timothy Henwood
Prevalence And Risk Factors For Low Habitual Walking Speed In Nursing Home Residents: An Observational Study, Justin Keogh, Hugh Senior, Elaine Beller, Timothy Henwood
Elaine Beller
OBJECTIVE To quantify habitual walking speed and estimate the prevalence of low habitual walking speed (<0.8m/s and <0.5m/s) in nursing home residents; and secondarily to gain some insight into whether demographic, health, and functional outcomes could predict the nursing home residents' walking speed. DESIGN Cross-sectional study. SETTING Eleven nursing homes. PARTICIPANTS Nursing home residents (N=102 [37%] of 273 eligible, randomly selected residents from 11 nursing homes consented to participate in this study). INTERVENTIONS Not applicable. MAIN OUTCOME MEASURES The primary outcome was habitual walking speed assessed over a distance of 2.4m. Secondary outcomes including body composition, muscle strength, balance …
Exercise Versus No Exercise For The Occurrence, Severity And Duration Of Acute Respiratory Infections (Review), Antonio Grande, J. Keogh, Tammy Hoffmann, Elaine Beller, Chris Del Mar
Exercise Versus No Exercise For The Occurrence, Severity And Duration Of Acute Respiratory Infections (Review), Antonio Grande, J. Keogh, Tammy Hoffmann, Elaine Beller, Chris Del Mar
Elaine Beller
Acute respiratory infections (ARIs) last for less than 30 days and are the most common acute diseases affecting people worldwide. Exercise has been shown to improve health generally and may be effective in reducing the occurrence, severity and duration of acute respiratory infections.
Increasing Value And Reducing Waste In Biomedical Research Regulations And Management, Rustam Salman, Elaine Beller, Jonathan Kagan, Elina Hemminki, Robert Phillips, Julian Savulescu, Malcolm Macleod, Janet Wisely, Iain Chalmers
Increasing Value And Reducing Waste In Biomedical Research Regulations And Management, Rustam Salman, Elaine Beller, Jonathan Kagan, Elina Hemminki, Robert Phillips, Julian Savulescu, Malcolm Macleod, Janet Wisely, Iain Chalmers
Elaine Beller
After identifi cation of an important research question and selection of an appropriate study design, waste can arise from the regulation, governance, and management of biomedical research. Obtaining regulatory and governance approval has become increasingly burdensome and disproportionate to the conceivable risks to research participants. Regulation and governance involve interventions that are assumed to be justifi ed in the interests of patients and the public, but they can actually compromise these interests. Ineffi cient management of the procedural conduct of research is wasteful, especially if it results in poor recruitment and retention of participants in well designed studies addressing important …
Palliative Pharmacological Sedation For Terminally Ill Adults (Review), Elaine Beller, Mieke Van Driel, Leanne Mcgregor, Shani Truong, Shani Mitchell
Palliative Pharmacological Sedation For Terminally Ill Adults (Review), Elaine Beller, Mieke Van Driel, Leanne Mcgregor, Shani Truong, Shani Mitchell
Elaine Beller
Terminally ill people experience a variety of symptoms in the last hours and days of life, including delirium, agitation, anxiety, terminal restlessness, dyspnoea, pain, vomiting, and psychological and physical distress. In the terminal phase of life, these symptomsmay become refractory, and unable to be controlled by supportive and palliative therapies specifically targeted to these symptoms. Palliative sedation therapy is one potential solution to providing relief from these refractory symptoms. Sedation in terminally ill people is intended to provide relief from refractory symptoms that are not controlled by other methods. Sedative drugs such as benzodiazepines are titrated to achieve the desired …
The Honeypot Randomized Controlled Trial Statistical Analysis Plan, Elaine Pascoe, Serigne Lô, Anish Scaria, Sunil Badve, Elaine Beller, Alan Cass
The Honeypot Randomized Controlled Trial Statistical Analysis Plan, Elaine Pascoe, Serigne Lô, Anish Scaria, Sunil Badve, Elaine Beller, Alan Cass
Elaine Beller
Background: The HONEYPOT study is a multicenter, open-label, blinded-outcome, randomized controlled trial designed to determine whether, compared with standard topical application of mupirocin for nasal staphylococcal carriage, exit-site application of antibacterial honey reduces the rate of catheter-associated infections in peritoneal dialysis patients. {black diamond suit} Objective: To make public the pre-specified statistical analysis principles to be adhered to and the procedures to be performed by statisticians who will analyze the data for the HONEYPOT trial. {black diamond suit} Methods: Statisticians and clinical investigators who were blinded to treatment allocation and treatment-related study results and who will remain blinded until the …
Antibacterial Honey For The Prevention Of Peritoneal-Dialysis-Related Infections (Honeypot): A Randomised Trial, David Johnson, Sunil Badve, Elaine Pascoe, Elaine Beller, Alan Cass, Carolyn Clark, Janak De Zoysa, Nicole Isbel, Douglas Mctaggart, Alicia Morrish, Geoffrey Playford, Anish Scaria, Paul Snelling, Liza Vergara, Carmel Hawley
Antibacterial Honey For The Prevention Of Peritoneal-Dialysis-Related Infections (Honeypot): A Randomised Trial, David Johnson, Sunil Badve, Elaine Pascoe, Elaine Beller, Alan Cass, Carolyn Clark, Janak De Zoysa, Nicole Isbel, Douglas Mctaggart, Alicia Morrish, Geoffrey Playford, Anish Scaria, Paul Snelling, Liza Vergara, Carmel Hawley
Elaine Beller
Background: There is a paucity of evidence to guide the best strategy for prevention of peritoneal-dialysis-related infections. Antibacterial honey has shown promise as a novel, cheap, effective, topical prophylactic agent without inducing microbial resistance. We therefore assessed whether daily application of honey at the exit site would increase the time to peritoneal-dialysis-related infections compared with standard exit-site care plus intranasal mupirocin prophylaxis for nasal carriers of Staphylococcus aureus. Methods: In this open-label trial undertaken in 26 centres in Australia and New Zealand, participants undergoing peritoneal dialysis were randomly assigned in a 1:1 ratio with an adaptive allocation algorithm to daily …
Prevalence Of Attention-Deficit/ Hyperactivity Disorder: A Systematic Review And Meta-Analysis, Rae Thomas, Sharon Sanders, Jenny Doust, Elaine Beller, Paul Glasziou
Prevalence Of Attention-Deficit/ Hyperactivity Disorder: A Systematic Review And Meta-Analysis, Rae Thomas, Sharon Sanders, Jenny Doust, Elaine Beller, Paul Glasziou
Elaine Beller
Overdiagnosis and underdiagnosis of attention-deficit/hyperactivity abstract disorder (ADHD) are widely debated, fueled by variations in prevalence estimates across countries, time, and broadening diagnostic criteria. We conducted a meta-analysis to: establish a benchmark pooled prevalence for ADHD; examine whether estimates have increased with publication of different editions of the Diagnostic and Statistical Manual of Mental Disorders (DSM); and explore the effect of study features on prevalence. METHODS: Medline, PsycINFO, CINAHL, Embase, and Web of Science were searched for studies with point prevalence estimates of ADHD. We included studies of children that used the diagnostic criteria from DSM-III, DSM-III-R and DSM-IV in …