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Modulation Of Soleus H-Reflex During Shortening And Lengthening Muscle Actions In Young And Older Adults, Yung-Sheng Chen, Shi Zhou, Colleen Cartwright
Modulation Of Soleus H-Reflex During Shortening And Lengthening Muscle Actions In Young And Older Adults, Yung-Sheng Chen, Shi Zhou, Colleen Cartwright
Professor Colleen M Cartwright
The Hoffmann reflex (H-reflex) is dependently modulated during isometric and anisometric muscle actions. However, the manner of the H-reflex modulation during dynamic muscle movements in relation to ageing is less stated in the literature. This study was designed to investigate the effects of ageing on soleus (SOL) H-reflex modulation during dynamic muscle actions. Twenty young (24±4 years of age) and 20 older adults (73±5 years of age) voluntarily participated in the study. The SOL H-reflex was measured during passive and active shortening and lengthening muscle actions in a sitting position. The older group showed a lower ratio of the maximal …
Cognition And Beta-Amyloid In Preclinical Alzheimer's Disease: Data From The Aibl Study, Kerryn Pike, Kathryn A Ellis, Victor L Villemagne, Norm Good, Gael Chetelat, David Ames, Cassandra Szoeke, Simon Laws, Giuseppe Verdile, Ralph Martins, Colin L Masters, Christopher C Rowe
Cognition And Beta-Amyloid In Preclinical Alzheimer's Disease: Data From The Aibl Study, Kerryn Pike, Kathryn A Ellis, Victor L Villemagne, Norm Good, Gael Chetelat, David Ames, Cassandra Szoeke, Simon Laws, Giuseppe Verdile, Ralph Martins, Colin L Masters, Christopher C Rowe
Simon Laws
The ‘preclinical’ phase of Alzheimer's disease is a future target for treatment, but additional research is essential to understand the relationship between β-amyloid burden and cognition during this time. We investigated this relationship using a large sample of apparently healthy older adults (N = 177), which also enabled examination of whether the relationship differed according to age, gender, years of education, apolipoprotein E status, and the presence of subjective memory complaints. In addition to episodic memory, a range of cognitive measures (global cognition, semantic memory, visuospatial performance, and executive function) were examined. Participants were aged over 60 years with no …