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Coping Styles, Opioid Blockade, And Cardiovascular Response To Stress, Stephen Bruehl, James Mccubbin, John Wilson, Thomas Montgomery, Paloma Ibarra, Charles Carlson Jul 2014

Coping Styles, Opioid Blockade, And Cardiovascular Response To Stress, Stephen Bruehl, James Mccubbin, John Wilson, Thomas Montgomery, Paloma Ibarra, Charles Carlson

James A. McCubbin

We investigated the hypothesis that the effects of Monitoring and Blunting coping styles are mediated in part by endogenous opioids. Mean arterial pressure (MAP) and heart rate (HR) were measured in 39 males before, during, and after a mental arithmetic stressor. Each subject experienced the protocol once under opioid blockade (naltrexone) and once in a placebo condition, in counterbalanced order. Monitoring and Blunting were assessed using the Miller Behavioral Style Scale. High Blunting and high Monitoring were both associated with poorer MAP recovery under opioid blockade than in the placebo condition. Similar effects were noted for Blunting on the measure …


Relaxation Training And Opioid Inhibition Of Blood Pressure Response To Stress, James Mccubbin, John Wilson, Stephen Bruehl, Paloma Ibarra, Charles Carlson, Jane Norton, George Colclough Jul 2014

Relaxation Training And Opioid Inhibition Of Blood Pressure Response To Stress, James Mccubbin, John Wilson, Stephen Bruehl, Paloma Ibarra, Charles Carlson, Jane Norton, George Colclough

James A. McCubbin

The present study was designed to determine the role of endogenous opioid mechanisms in the circulatory effects of relaxation training. Opioid mechanisms were assessed by examination of the effects of opioid receptor blockade with naltrexone on acute cardiovascular reactivity to laboratory stress before and after relaxation training. 32 young men with mildly elevated casual arterial pressure were recruited for placebo-controlled naltrexone stress tests and relaxation training. The results indicated that relaxation training significantly reduced the diastolic pressure response to mental arithmetic stress. Opioid receptor blockade with naltrexone antagonized the effects of relaxation training. These findings suggest that some of the …


Emotional Dampening In Persons With Elevated Blood Pressure: Affect Dysregulation And Risk For Hypertension, James Mccubbin, J Loveless, J Graham, D Moore, G Hall, R Bart, M Merritt, R Lane, J Thayer Jul 2014

Emotional Dampening In Persons With Elevated Blood Pressure: Affect Dysregulation And Risk For Hypertension, James Mccubbin, J Loveless, J Graham, D Moore, G Hall, R Bart, M Merritt, R Lane, J Thayer

James A. McCubbin

Background Persons with higher blood pressure have emotional dampening in some contexts. This may reflect interactive changes in central nervous system control of affect and autonomic function in the early stages of hypertension development. Purpose The purpose of this study is to determine the independence of cardiovascular emotional dampening from alexithymia to better understand the role of affect dysregulation in blood pressure elevations. Methods Ninety-six normotensives were assessed for resting systolic and diastolic (DBP) blood pressure, recognition of emotions in faces and sentences using the Perception of Affect Task (PAT), alexithymia, anxiety, and defensiveness. Results Resting DBP significantly predicted PAT …


Effects Of Stretch-Based Progressive Relaxation Training On The Secretion Of Salivary Immunoglobulin A In Orofacial Pain Patients, Jeffrey Sherman, Charles Carlson, James Mccubbin, John Wilson Jul 2014

Effects Of Stretch-Based Progressive Relaxation Training On The Secretion Of Salivary Immunoglobulin A In Orofacial Pain Patients, Jeffrey Sherman, Charles Carlson, James Mccubbin, John Wilson

James A. McCubbin

There is a growing body of evidence that psychologic stressors can affect physical health and proneness to disease through depletion of the body's immune system. Relatively little research, however, has investigated the potential immunoenhancing effect of stress-relieving strategies such as progressive muscle relaxation. This study explored the relationship between immune functioning and relaxation training with persons experiencing persistent facial pain. In a single experimental session, 21 subjects either received relaxation training or rested for an equivalent time period. Salivary immunoglobulin A, mood, pain, and tension levels were measured before and after relaxation and rest periods. Results indicated that a greater …