Medicine and Health Sciences Commons^™

Mycobacterium Chelonae Associated With Rapid Erosion Of Non-Sutured Laparoscopic Gastric Band, Muhammed Ashraf Memon, Breda Memon, Michael Whitby

Muhammed Ashraf Memon

Introduction

To describe a case of rapidly eroded laparoscopic placed non-sutured gastric band secondary to Mycobacterium chelonae.

Presentation of case

A 65 year old male, who had undergone laparoscopic gastric banding two months prior for morbid obesity, presented to the clinic complaining of abdominal pain and night time fever of 4 days duration. Urgent gastroscopy revealed eroded gastric band which was removed laparoscopically.

Discussion

M. chelonae are not uncommon in Queensland. Although the mode of acquisition of infection remains unclear, it is suspected that human disease results from environmental exposure to dirty soil and water. The patient lives in rural …

Cd36 And Na/K-Atpase- Α 1 Form A Proinflammatory Signaling Loop In Kidney, David Kennedy, Yiliang Chen, Wenxin Huang, Jamie Viterna, Jiang Liu, Kristen Westfall, Jian Tian, David Bartlett, W.H. Tang, Zijian Xie, Joseph Shapiro, Roy Silverstein

Jiang Liu

Proatherogenic, hyperlipidemic states demonstrate increases in circulating ligands for scavenger receptor CD36 (eg, oxidized low-density lipoprotein [oxLDL]) and the Na/K-ATPase (eg, cardiotonic steroids). These factors increase inflammation, oxidative stress, and progression of chronic kidney disease. We hypothesized that diet-induced obesity and hyperlipidemia potentiate a CD36/Na/K-ATPase–dependent inflammatory paracrine loop between proximal tubule cells (PTCs) and their associated macrophages and thereby facilitate development of chronic inflammation and tubulointerstitial fibrosis. ApoE^-/- and apoE^-/-/cd36^-/- mice were fed a high-fat diet for ≤32 weeks and examined for physiologic and histologic changes in renal function. Compared with apoE^-/-, apoE^{-/- …}

Obesity And Serum High Sensitivity C-Reactive Protein Levels Among Elderly Turkish Immigrants In The Netherlands With Type 2 Diabetes, Shiryn Sukhram, Gustavo Zarini, Lamya Shaban, Joan Vaccaro, Fatma Huffman

Joan A. Vaccaro

The study examined the associations of anthropometric measures of obesity with high sensitivity C-reactive protein (hs-CRP) levels in Turkish immigrants with type 2 diabetes (T2D) living in the Netherlands. A total of 110 participants, physician-diagnosed with T2D, aged 30 years and older were recruited from multiple sources from The Hague, Netherlands. Serum hs-CRP levels were measured with immunoturbidimetric assay. Glycated hemoglobin (A1C) was determined by high-pressure liquid chromatography. Measures of obesity: body weight, body mass index (BMI), waist circumference (WC), hip circumference (HC), waist-to-hip ratio (WHR), and waist-to-height ratio (WHtR) were determined. Statistical analysis included descriptive statistics, Pearson’s correlations and …

Acculturation, Physical Activity, And Obesity Among Hispanic Adolescents, Jihong Liu, Janice Probst, Nusrat Harun, Kevin Bennett, Myriam Torres

Jihong Liu

No abstract provided.

Treatment Of Adult Obesity With Bariatric Surgery, Robin Schroeder, Jordan Garrison, Mark Johnson

Robin S. Schroeder MD

Bariatric surgery procedures, including laparoscopic adjustable gastric banding, laparoscopic sleeve gastrectomy, and Roux-en-Y gastric bypass, result in an average weight loss of 50 percent of excess body weight. Remission of diabetes mellitus occurs in approximately 80 percent of patients after Roux-en-Y gastric bypass. Other obesity-related comorbidities are greatly reduced, and health-related quality of life improves. The Obesity Surgery Mortality Risk Score can help identify patients with increased mortality risk from bariatric surgery. Complications and adverse effects are lowest with laparoscopic surgery, and vary by procedure and presurgical risk. The Roux-en-Y procedure carries an increased risk of malabsorption sequelae, which can …

Birth Weight And Obesity Risk At First Grade In A Cohort Of Chilean Children, S. Loaiza, Alberto Coustasse, X. Urrutia-Rojas, E. Atalah

Alberto Coustasse

The purpose of the study was to determine the association of birth weight as a risk factor for obesity at first grade in a cohort of elementary school Chilean children. Height and weight at birth and follow up measurements at first grade were analyzed from a national cohort of 119,070 new borns. Subjects were classified by anthropometric characteristics: new born weight in kilograms, Ponderal Index, (birth weight/height³ x 100), and gestational age (physical maturity) categories at birth. The study tested the hypothesis that a macrocosomic newborn (4,000 g or > 8.8 pounds) or Large for Gestational Age , would be …

“A Little On The Heavy Side”: A Qualitative Analysis Of Parents' And Grandparents' Perceptions Of Preschoolers' Body Weights, Karin Eli, Kyndal Howell, Philip Fisher, Paulina Nowicka

Karin Eli

Objectives: Parents’ difficulties in perceiving children's weight status accurately pose a barrier for family-based obesity interventions; however, the factors underlying weight misinterpretation still need to be identified. This study's objective was to examine parents and grandparents’ perceptions of preschoolers’ body sizes. Interview questions also explored perceptions of parental responsibility for childhood obesity and appropriate contexts in which to discuss preschoolers’ weights. Design: Semistructured interviews, which were videotaped, transcribed and analysed qualitatively. Setting: Eugene and the Springfield metropolitan area, Oregon, USA Participants: Families of children aged 3–5 years were recruited in February—May 2011 through advertisements about the study, published in the …

Preventing Paediatric Obesity; Recommendations From A Community-Based Qualitative Investigation, Patricia Tucker, Jennifer Irwin, L. Sangster Bouck, Meizi He, G. Pollett

Trish Tucker

Childhood obesity is on the rise, and interventions targeted at pre-school-aged children are essential for the primary prevention of this disease. Physical activity programming and decreasing screen viewing may be advantageous ways to reduce the early onset of obesity. Parents' perceptions regarding effective tools and programmes to target obesity are needed to develop an efficacious programme. Ten semi-structured focus groups were conducted for this qualitative study. Two experienced moderators facilitated all focus groups which were conducted in local day cares, workplaces and play groups, frequented by parents. All focus groups were audio-recorded and transcribed verbatim. Strategies to ensure trustworthiness of …

Preschoolers' Physical Activity Behaviours: Parents' Perspectives, Jennifer Irwin, Meizi He, L. Sangster Bouck, Patricia Tucker, Graham Pollett

Trish Tucker

OBJECTIVES: To understand parents' perspectives of their preschoolers' physical activity behaviours. METHODS: A maximum variation sample of 71 parents explored their preschoolers' physical activity behaviours through 10 semi-structured focus group discussions. RESULTS: Parents perceived Canada's Physical Activity Guidelines for Children as inadequate; that their preschoolers get and need more than 30-90 minutes of activity daily; and that physical activity habits must be established during the preschool years. Nine barriers against and facilitators toward adequate physical activity were proposed: child's age, weather, daycare, siblings, finances, time, society and safety, parents' impact, and child's activity preferences. DISCUSSION: The need for education and …

Screen-Viewing Behaviors Among Preschoolers Parents' Perceptions, Meizi He, Jennifer Irwin, L. Sangster Bouck, Patricia Tucker, Graham Pollett

Trish Tucker

BACKGROUND: Childhood obesity has emerged as a public health concern in Canada. It has been suggested that excessive screen viewing (i.e., television, computer, video) is a major factor contributing to the increased risk of obesity in children. Exploring young children's experiences with this modifiable behavior may be beneficial to the creation of a multifaceted program aimed at the primary prevention of obesity. OBJECTIVES: To seek parents' perceptions and insights pertaining to their preschoolers' screen-viewing behaviors. METHODS: This qualitative study targeted a heterogeneous sample of parents with children aged 2.5 to 5 years. Two experienced moderators using a semistructured interview guide …

Obesity, Weight Change, And Risk Of Adenoma Recurrence: A Prospective Trial, Adeyinka Laiyemo, Chyke Doubeni, Dilhana Badurdeen, Gillian Murphy, Pamela Marcus, Robert Schoen, E. Lanza, Duane Smoot, A. Cross

Chyke A. Doubeni

BACKGROUND AND STUDY AIMS: Obesity is a risk factor for colorectal neoplasia. Lifestyle modifications, including weight loss, have been advocated to reduce the risk. However, no prospective study has evaluated whether weight loss actually affects adenoma recurrence. The aim of this study was to examine whether weight change (loss or gain) over 4 years is associated with adenoma recurrence. PATIENTS AND METHODS: A total of 1826 patients with colorectal adenoma in the Polyp Prevention Trial had their height and weight measured at baseline. Adenoma recurrence was determined by end of trial colonoscopy 4 years after study entry when patients' weights …

The Impact Of Co-Active Life Coaching On Female University Students With Obesity, Melissa Van Zandvoort, Jennifer Irwin, Don Morrow

Donald Morrow

The purpose of this qualitative study was to explore the impact of Co-active life coaching on obese female university students. Five obese (BMI ≥ 30kg/m2), female university students received an average of nine weekly, 35-minute, one-on-one sessions with a certified coach. Semi- structured, in-depth interviews before and after participating in the coaching intervention were conducted, and inductive content analysis was utilized. Strategies to enhance data trustworthiness were incorporated throughout. Participants initially reported: struggling with barriers and experiencing pressure from family to lose weight; negative relationships with themselves; feeling self-conscious and remorse for their size and lifestyle choices. At the conclusion …

Participants' Perceived Utility Of Motivational Interviewing Using Co-Active Life Coaching Skills On Their Struggle With Obesity, Courtney Newnham-Kanas, Don Morrow, Jennifer Irwin

Donald Morrow

The purpose of this qualitative study was to investigate the impact of Motivational Interviewing (MI) using Co-Active Life Coaching skills as a treatment for adults (age, 35–55 years) struggling with obesity. Eight women (BMI≥30) who reside in London, Ontario, received 18 coaching sessions over six months with a Certified Professional Co-Active (CPCC) coach. Participants engaged in semi-structured pre- and post-interviews, along with a focus group six months after the last coaching session. The study's CPCC was also interviewed post-intervention to gain an understanding of what it was like coaching this population. All interviews were analysed using inductive content analysis. Following …

Contribution Of Behavioral Risk Factors And Obesity To Socioeconomic Differences In Colorectal Cancer Incidence, Chyke Doubeni, Jacqueline Major, Adeyinka Laiyemo, Mario Schootman, Ann Zauber, Albert Hollenbeck, Rashmi Sinha, Jeroan Allison

Chyke A. Doubeni

BACKGROUND:Health behaviors are known risk factors for colorectal cancer and are more common in low socioeconomic status (SES) populations. We evaluated the extent to which behavioral risk factors and body mass index (BMI) explain SES disparities in colorectal cancer incidence, overall and by tumor location.

METHODS: We analyzed prospective National Institutes of Health-AARP Diet and Health Study data on 506 488 participants who were recruited in 1995-1996 from six US states and two metropolitan areas and followed through 2006. Detailed baseline data on risk factors for colorectal cancer, including health behaviors, were obtained using questionnaires. SES was measured by self-reported …

A Link Between Chronic Sleep Restriction And Obesity: Methodological Considerations, Christopher Magee, Donald Iverson, Xu-Feng Huang, Peter Caputi

Xu-Feng Huang

Emerging evidence suggests that chronicsleeprestriction contributes to obesity. Targeting short sleep duration may therefore offer a novel and effective method of preventing and treating obesity. However, this area of research is only in its infancy, and a complete understanding of how chronicsleeprestriction and obesity are linked is currently lacking. The aim of this paper is to briefly review epidemiological evidence for an association between chronicsleeprestriction and obesity in adults, and outline the key methodological limitations of these studies. Particular attention is paid to the methods used to measure sleep and obesity, as well as the need to control for potential …

Effects Of Diets High In Whey, Soy, Red Meat And Milk Protein On Body Weight Maintenance In Diet-Induced Obesity In Mice, Xu-Feng Huang, Y Liu, Gita Rahardjo, Peter Mclennan, Linda Tapsell, William Buttemer

Xu-Feng Huang

This study examined the effects of different food sources of protein on energy intake, body weight maintenance, and on the responses of plasma leptin, insulin and adiponectin in chronic high-fat diet-induced obese mice. Obesity was induced in 47 mice with a high-fat diet for 20 weeks. They were divided into five diet groups to test the effects of a higher protein proportion (30% energy), achieved at the expense of carbohydrate. For the next eight weeks, four of the groups were fed diets of chow formulated with whey, soy, red meat or milk while the control group continued on their high-fat …

A Link Between Chronic Sleep Restriction And Obesity: Methodological Considerations, Christopher Magee, Donald Iverson, Xu-Feng Huang, Peter Caputi

Don C. Iverson

Emerging evidence suggests that chronicsleeprestriction contributes to obesity. Targeting short sleep duration may therefore offer a novel and effective method of preventing and treating obesity. However, this area of research is only in its infancy, and a complete understanding of how chronicsleeprestriction and obesity are linked is currently lacking. The aim of this paper is to briefly review epidemiological evidence for an association between chronicsleeprestriction and obesity in adults, and outline the key methodological limitations of these studies. Particular attention is paid to the methods used to measure sleep and obesity, as well as the need to control for potential …

Family Practice Residents' Identification And Management Of Obesity, R Mcartor, Donald Iverson, D Benken, L Dennis

Don C. Iverson

This study, involving 25 family practice residents and 2746 patients in a family practice residency programme, addressed four hypotheses regarding the identification and management of obesity in the primary care setting: (i) the physician-identified prevalence of obesity is significantly lower than the actual prevalence in the population, (ii) obesity is more likely to be addressed with management actions when it is recorded on the medical record problem list than when it is not recorded, (iii) physician actions dealing with obesity are influenced by the patient's age, sex, level of motivation, and body mass index (BMI) value, and (iv) the type …

Assessing The Effectiveness Of Intuitive Eating For Weight Loss - Pilot Study, Judith Anglin

Judith C Anglin

The obesity epidemic is widely recognized as a major public health issue resulting in chronic diseases. Calorie restriction (CR) is frequently used for most weight loss programs. The intuitive eating (IE) approach uses an individual's response to internal cues of hunger, satiety, and appetite and replaces CR. The study was a randomized controlled trial with two groups that assessed the anthropometric measurements of obese adults using CR and IE to achieve weight loss. The participants were sedentary obese individuals with no history of chronic diseases. They engaged in physical activity three times per week for 30 minutes and recorded their …

The Change Program: Comparing An Interactive Versus Prescriptive Obesity Intervention On University Students' Self-Esteem And Functional Health Status, Erin Pearson, Jennifer Irwin, Don Morrow

Donald Morrow

Background: Previous studies incorporating Motivational Interviewing administered via Co‐Active Life Coaching tools (MI‐via‐CALC) have elicited positive results among adults with obesity. However, there is a paucity of this research that includes sufficient power and a comparison group. This study's purpose was to compare MI‐via‐CALC with a validated obesity intervention among university students. Methods: Participants (n = 45) were randomised to either a telephone‐based 12‐week: (a) MI‐via‐CALC program whereby a certified coach worked with subjects to achieve goals through dialogue; or (b) lifestyle modification treatment following the LEARN Program for Weight Management. Participants completed the Rosenberg Self‐Esteem Scale and Short Form …

The Change Program: Comparing An Interactive Versus Prescriptive Obesity Intervention On University Students’ Self-Esteem And Quality Of Life, Don Morrow, Erin Pearson, Jennifer Irwin, Hall Craig

Donald Morrow

Previous studies incorporating Motivational Interviewing administered via Co-Active Life Coaching tools (MI-via-CALC) have elicited positive results among adults with obesity. However, there is a paucity of this research that includes sufficient power and a comparison group. This study’s purpose was to compare MI-via-CALC with a validated obesity intervention among university students. Methods: Participants (n = 45) were randomised to either a telephone-based 12-week: (a) MI-via-CALC program whereby a certified coach worked with subjects to achieve goals through dialogue; or (b) lifestyle modification treatment following the LEARN Program for Weight Management. Participants completed the Rosenberg Self-Esteem Scale and Short Form Functional …

Overweight And Obesity Among White, Black, And Mexican American Children: Implications For When To Intervene, Janice Long, Nicole Mareno, Rebecca Shabo, Astrid Wilson

Nicole Mareno

Ways To Enhance Children's Activity And Nutrition (We Can)--A Pilot Project With Latina Mothers, Kathy James, Cynthia Connelly, Luz Garcia, Nicole Mareno, Janice Baietto

Nicole Mareno

Body Mass Index, Treatment Practices, And Mortality In Patients With Acute Heart Failure, Timothy Fitzgibbons, Olga Hardy, Darleen Lessard, Joel Gore, Jorge Yarzebski, Robert Goldberg

Jorge L. Yarzebski

OBJECTIVES: Obesity is associated with an increased risk of heart failure (HF). Among patients presenting with acute HF, however, differences in clinical characteristics, treatment regimens, and short-term prognosis of varying weights are largely unknown, particularly from a broader population-based perspective. METHODS: A total of 3722 patients admitted with acute HF to 11 greater Worcester (Massachusetts, USA) hospitals during 1995 and 2000 were categorized as being lean (n = 216), normal weight (n = 1465), overweight (n = 1007), or obese (n = 1034) at the time of hospitalization. RESULTS: Obese patients with decompensated HF were significantly younger (mean age = …

Diverse Regulation Of Nf-Kappab And Peroxisome Proliferator-Activated Receptors In Murine Nonalcoholic Fatty Liver, Laszlo Romics, Karen Kodys, Angela Dolganiuc, Lucia Graham, Arumugam Velayudham, Pranoti Mandrekar, Gyongyi Szabo

Gyongyi Szabo

Fatty liver is highly sensitive to inflammatory activation. Peroxisome proliferator-activated receptors (PPAR) have anti-inflammatory effects and regulate lipid metabolism in the fatty liver. We hypothesized that fatty liver leads to endotoxin sensitivity through an imbalance between pro- and anti-inflammatory signals. Leptin-deficient, ob/ob mice and their lean littermates were challenged with single or double insults and pro- and anti-inflammatory pathways were tested on cytokine production and activation of nuclear regulatory factors NF-kappaB and peroxisome proliferator receptor element (PPRE). Ob/ob mice produced significantly higher serum tumor necrosis factor alpha (TNF-alpha) and interleukin (IL) 6 and showed increased hepatic NF-kappaB activation compared to …

Family-Based Weight Management With Latino Mothers And Children, Kathy James, Cynthia Connelly, Elaine Rutkowski, Darlene Mcpherson, Luz Garcia, Nicole Mareno, Dorothy Zirkle

Nicole Mareno