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Selected Works

1988

Articles 1 - 2 of 2

Full-Text Articles in Medicine and Health Sciences

S-Antigen In A Hereditary Visual Cell Disease. Immunocytochemical And Immunological Studies, Gustavo D. Aguirre, K Long, N Philp, I Gery Oct 1988

S-Antigen In A Hereditary Visual Cell Disease. Immunocytochemical And Immunological Studies, Gustavo D. Aguirre, K Long, N Philp, I Gery

Gustavo D. Aguirre, VMD, PhD

S-antigen is a photoreceptor-specific and potentially autoantigenic protein. Using light microscopic immunocytochemistry, the localization of S-antigen was studied in the retinas of normal dogs and Irish setters affected with rod-cone dysplasia, a hereditary retinal degeneration characterized by abnormal cGMP metabolism and arrested outer segment differentiation. Normal and affected dogs were also tested for the presence of humoral and cellular immunity to S-antigen. S-antigen was present in both rods and cones during inner and outer segment differentiation, but there was an apparent loss of immunoreactivity in cones as the retina matured. The developmental appearance and localization of S-antigen in affected retinas …

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Vitamin D And Parotid Gland Function In The Rat, C. Peterfy, A. Tenenhouse, E. Yu Mar 1988

Vitamin D And Parotid Gland Function In The Rat, C. Peterfy, A. Tenenhouse, E. Yu

Edward Yu

1. We previously reported that parotid gland secretion is decreased in rats deprived of vitamin D (Glijer, Peterfy & Tenenhouse, 1985). In the present study we examine whether this effect is a direct result of the absence of vitamin D or due to the secondary systemic effects of vitamin D deficiency. 2. Offspring of rats maintained on a calcium-supplemented (1.2%), vitamin-D-deficient diet were weaned onto the same diet and examined after 8 weeks. Using this method it was possible to maintain serum calcium and parathyroid hormone concentrations within normal limits. Serum 25-hydroxyvitamin D (25(OH)D3) was not detectable, but 1,25-dihydroxyvitamin D …

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