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The Honeypot Study Protocol: A Randomised Controlled Trial Of Exit Site Application Of Medihoney Antibacterial Wound Gel For The Prevention Of Catheter-Associated Infections In Peritoneal Dialysis Patients, David Johnson, Carolyn Clark, Nicole Isbel, Carmel Hawley, Elaine Beller, Alan Cass, Janak De Zoysa, Steven Mctaggart, Geoffrey Playford, Brenda Rosser, Charles Thompson, Paul Snelling
The Honeypot Study Protocol: A Randomised Controlled Trial Of Exit Site Application Of Medihoney Antibacterial Wound Gel For The Prevention Of Catheter-Associated Infections In Peritoneal Dialysis Patients, David Johnson, Carolyn Clark, Nicole Isbel, Carmel Hawley, Elaine Beller, Alan Cass, Janak De Zoysa, Steven Mctaggart, Geoffrey Playford, Brenda Rosser, Charles Thompson, Paul Snelling
Elaine Beller
Objectives: The primary objective of this study is to determine whether daily exit-site application of standardized antibacterial honey (Medihoney Antibacterial Wound Gel; Comvita, Te Puke, New Zealand) results in a reduced risk of catheter-associated infections in peritoneal dialysis (PD) patients compared with standard topical mupirocin prophylaxis of nasal staphylococcal carriers.
Design: Multicenter, prospective, open label, randomized controlled trial.
Setting: PD units throughout Australia and New Zealand.
Participants: The study will include both incident and prevalent PD patients (adults and children) for whom informed consent can be provided. Patients will be excluded if they have had (1) a history of psychological …