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Vasoactive Neuropeptides In Autoimmune Diseases, Ekua Brenu, Lotti Tajouri, Donald Staines, Sonya Marshall-Gradisnik
Vasoactive Neuropeptides In Autoimmune Diseases, Ekua Brenu, Lotti Tajouri, Donald Staines, Sonya Marshall-Gradisnik
Lotti Tajouri
Extract:Neuropeptides are a class of regulatory peptides with effects in nearly all physiological systems and processes. They are important in facilitating neuroendocrine immune interactions. Bi-directional communication between these two systems in both the central nervous system (CNS) and the periphery are arbitrated by the presence of these peptidergic innervations. These innervations interacting through unique ligand receptor binding complexes have immunomodulatory effects that preserve neuroendocrine and neuroimmune health.
Mechanism Of Autoimmunity In Pregnancy - The Good And The Bad, Lotti Tajouri, Ekua Brenu, Donald Staines, Sonya Marshall-Gradisnik
Mechanism Of Autoimmunity In Pregnancy - The Good And The Bad, Lotti Tajouri, Ekua Brenu, Donald Staines, Sonya Marshall-Gradisnik
Lotti Tajouri
Extract:In humans, female’s humoral and cellular immunity are actually stronger than men (Nalbandian & Kovats, 2005) and present a higher antibody serum titration than men (Giron-Gonzalez et al., 2000) which could logically and possibly explain their gender predisposition and susceptibility to autoimmunity. Holding an autoimmune disease and becoming pregnant is a serious matter for a woman and knowledge of the course of the condition during pregnancy is essential. Relational variations exist between types of autoimmuny during pregnancy and consequently proper advices from physicians are provided accordingly. In Systemic lupus erythematosus, all advices provided to the patients are meant to dissuade …