Open Access. Powered by Scholars. Published by Universities.®
- Keyword
-
- Department of Medicine (15)
- Cardiology Division (13)
- Department of Emergency Medicine (8)
- Department of Emergency Medicine Faculty (8)
- Female (5)
-
- Humans (5)
- Male (5)
- Middle Aged (5)
- Aged (4)
- Department of Medicine Faculty (4)
- Department of Medicine Fellows and Residents (4)
- Adult (3)
- Administration and Leadership (2)
- Anti-Arrhythmia Agents (2)
- Atrial Fibrillation (2)
- Catheter Ablation (2)
- Department of Community Health and Health Studies (2)
- Department of Emergency Medicine Residents (2)
- Heart Rate (2)
- Patient Care Services / Nursing (2)
- Pediatrics (2)
- Prospective Studies (2)
- Retrospective Studies (2)
- Stroke (2)
- UMCCTS funding (2)
- *Forecasting (1)
- *Hospitalization (1)
- Algorithms (1)
- Angiography (1)
- Assessment (1)
Articles 1 - 25 of 25
Full-Text Articles in Medicine and Health Sciences
Sildenafil For The Treatment Of Pulmonary Hypertension In Pediatric Patients, Alice Huddleston, Chad Knoderer, Jennifer Morris, Eric Ebenroth
Sildenafil For The Treatment Of Pulmonary Hypertension In Pediatric Patients, Alice Huddleston, Chad Knoderer, Jennifer Morris, Eric Ebenroth
Chad A. Knoderer
Sildenafil is a phosphodiesterase 5 inhibitor widely used for the treatment of pulmonary hypertension in children. Despite limited available safety and efficacy evidence, use of sildenafil continues to increase. To date, sildenafil use for pediatric pulmonary hypertension has been characterized for 193 children through 16 studies and 28 case series and reports. The primary efficacy data suggest that sildenafil is beneficial for facilitating the weaning of inhaled nitric oxide in children after cardiac surgery. Compiled safety data suggest that sildenafil is well tolerated among children with idiopathic pulmonary arterial hypertension and pulmonary arterial hypertension associated with congenital heart disease. This …
Efficacy Of Limited Cefuroxime Prophylaxis In Pediatric Patients After Cardiovascular Surgery, Chad Knoderer, Elaine Cox, Michelle Berg, Andrea Webster, Mark Turrentine
Efficacy Of Limited Cefuroxime Prophylaxis In Pediatric Patients After Cardiovascular Surgery, Chad Knoderer, Elaine Cox, Michelle Berg, Andrea Webster, Mark Turrentine
Chad A. Knoderer
Purpose The efficacy of limited cefuroxime prophylaxis in pediatric patients after cardiovascular surgery was evaluated. Methods All patients age 18 years or younger who underwent cardiovascular surgery and received postoperative care from the cardiovascular surgery team between February and July 2006 (preintervention group) and between August 2006 and January 2007 (postintervention group) were eligible for study inclusion. Patients were excluded if they did not receive cefuroxime as postoperative prophylaxis, had a preexisting infection, underwent cardiac transplantation or extracorporeal membrane oxygenation, or underwent delayed sternal closure. The preintervention group received prolonged cefuroxime prophylaxis, and the postintervention group received 24 hours of …
30-Year Trends In Patient Characteristics, Treatment Practices, And Long-Term Outcomes Of Adults Aged 35 To 54 Years Hospitalized With Acute Myocardial Infarction, Mayra Tisminetzky, David Mcmanus, Joel Gore, Jorge Yarzebski, Andrew Coles, Darleen Lessard, Robert Goldberg
30-Year Trends In Patient Characteristics, Treatment Practices, And Long-Term Outcomes Of Adults Aged 35 To 54 Years Hospitalized With Acute Myocardial Infarction, Mayra Tisminetzky, David Mcmanus, Joel Gore, Jorge Yarzebski, Andrew Coles, Darleen Lessard, Robert Goldberg
Jorge L. Yarzebski
Much of our knowledge about the characteristics, clinical management, and postdischarge outcomes of acute myocardial infarction (AMI) is derived from clinical studies in middle-aged and older subjects with little contemporary information available about the descriptive epidemiology of AMI in relatively young men and women. The objectives of our population-based study were to describe >3-decade-long trends in the clinical features, treatment practices, and long-term outcomes of young adults aged 35 to 54 years discharged from the hospital after AMI. The study population consisted of 2,142 residents of the Worcester (Massachusetts) metropolitan area who were hospitalized with AMI at all central Massachusetts …
Decade-Long Trends In The Characteristics, Management And Hospital Outcomes Of Diabetic Patients With St-Segment Elevation Myocardial Infarction, Mayra Tisminetzky, Samuel Joffe, David Mcmanus, Chad Darling, Joel Gore, Jorge Yarzebski, Darleen Lessard, Robert Goldberg
Decade-Long Trends In The Characteristics, Management And Hospital Outcomes Of Diabetic Patients With St-Segment Elevation Myocardial Infarction, Mayra Tisminetzky, Samuel Joffe, David Mcmanus, Chad Darling, Joel Gore, Jorge Yarzebski, Darleen Lessard, Robert Goldberg
Jorge L. Yarzebski
PURPOSE: Our objectives were to describe recent trends in the characteristics and in-hospital outcomes in diabetic as compared with non-diabetic patients hospitalized with ST-segment elevation myocardial infarction (STEMI).
METHODS: We reviewed the medical records of 2537 persons with (n = 684) and without (n = 1853) a history of diabetes who were hospitalized for STEMI between 1997 and 2009 at 11 medical centres in Central Massachusetts.
RESULTS: Diabetic patients were more likely to be older, female and to have a higher prevalence of previously diagnosed comorbidities. Diabetic patients were more likely to have developed important in-hospital complications and to have …
In-Hospital Depression Predicts Early Hospital Readmission After An Acute Coronary Syndrome: Preliminary Data From Trace-Core, David Mcmanus, Jane Saczynski, Molly Waring, Milena Anatchkova, Richard Mcmanus, Robert Goldberg, Jeroan Allison, David Parish, Hamza Awad, Jerry Gurwitz, Arlene Ash, Catarina Kiefe
In-Hospital Depression Predicts Early Hospital Readmission After An Acute Coronary Syndrome: Preliminary Data From Trace-Core, David Mcmanus, Jane Saczynski, Molly Waring, Milena Anatchkova, Richard Mcmanus, Robert Goldberg, Jeroan Allison, David Parish, Hamza Awad, Jerry Gurwitz, Arlene Ash, Catarina Kiefe
Richard H. McManus
Background: Hospital systems, patients and providers seek to avert rehospitalizations within 30 days for patients admitted with an acute coronary syndrome (ACS). Rehospitalizations within 30 days of discharge are often considered preventable and to reflect poor in-hospital management or discharge practices. However, independent associations of psychosocial factors with early rehospitalization in patients admitted with an ACS have not been examined. Methods: A multi-racial cohort of 1,540 patients admitted with an ACS reported psychosocial factors via standardized questionnaires in an in-hospital interview. One month following discharge, patients were interviewed via phone and reported hospital readmissions. We used logistic regression models to …
Long-Term Survival For Patients With Acute Decompensated Heart Failure According To Ejection Fraction Findings, Andrew Coles, Kimberly Fisher, Chad Darling, Jorge Yarzebski, David Mcmanus, Joel Gore, Darleen Lessard, Robert Goldberg
Long-Term Survival For Patients With Acute Decompensated Heart Failure According To Ejection Fraction Findings, Andrew Coles, Kimberly Fisher, Chad Darling, Jorge Yarzebski, David Mcmanus, Joel Gore, Darleen Lessard, Robert Goldberg
Jorge L. Yarzebski
Limited data exist about the long-term prognosis of patients with acute decompensated heart failure (ADHF) further stratified according to ejection fraction (EF) findings. The primary objective of this population-based observational study was to characterize and compare trends in long-term prognosis after an episode of ADHF across 3 EF strata. Hospital medical records were reviewed for 3,604 residents of the Worcester, Massachusetts, metropolitan area who were discharged after ADHF from all 11 medical centers in central Massachusetts during 1995, 2000, 2002, and 2004 and had EF measurements during their index hospitalizations. The average age of this population was 75 years, most …
Sex Differences In Cardiac Arrest Survivors Who Receive Therapeutic Hypothermia, Marna Greenberg, Amy Ahnert, Nainesh Patel, Courtney Bennett, Nicole Elliott, Mark Lundquist, Andrew Miller, Ellina Feiner, Anita Kurt, Bernadette Gl-Porter, Mercedes Rios-Scott, David Burmeister
Sex Differences In Cardiac Arrest Survivors Who Receive Therapeutic Hypothermia, Marna Greenberg, Amy Ahnert, Nainesh Patel, Courtney Bennett, Nicole Elliott, Mark Lundquist, Andrew Miller, Ellina Feiner, Anita Kurt, Bernadette Gl-Porter, Mercedes Rios-Scott, David Burmeister
Marna R Greenberg DO, MPH, FACEP
OBJECTIVE: Sex differences have not been well defined for patients undergoing therapeutic hypothermia (TH). We aimed to determine sex differences in mortality and Cerebral Performance Category (CPC) scores at discharge among those receiving TH. METHODS: This retrospective cohort study used data abstracted from an "ICE alert" database, an institutional protocol expediting mild TH for postarrest patients. Quality assurance variables (such as age, time to TH, CPC scores, and mortality) were reviewed and compared by sex. χ(2) Test and Wilcoxon rank sum test were used. Stepwise logistic regression was used to assess the association between mortality and sex, while controlling for …
Diagnostic Performance Of Cardiac Troponin I For Early Rule-In And Rule-Out Of Acute Myocardial Infarction: Results Of A Prospective Multicenter Trial, Alan Storrow, Robert Christenson, Richard Nowak, Deborah Diercks, Adam Singer, Alan Wu, Erik Kulstad, Frank Lovecchio, Christian Fromm, Gary Headden, Tracie Potis, Christopher Hogan, Jon Schrock, Daniel Zelinski, Marna Greenberg, James Ritchie, Janna Chamberlin, Kurtis Bray, Daniel Rhodes, Deirdre Trainor, Dawn Holmes, Paula Southwick
Diagnostic Performance Of Cardiac Troponin I For Early Rule-In And Rule-Out Of Acute Myocardial Infarction: Results Of A Prospective Multicenter Trial, Alan Storrow, Robert Christenson, Richard Nowak, Deborah Diercks, Adam Singer, Alan Wu, Erik Kulstad, Frank Lovecchio, Christian Fromm, Gary Headden, Tracie Potis, Christopher Hogan, Jon Schrock, Daniel Zelinski, Marna Greenberg, James Ritchie, Janna Chamberlin, Kurtis Bray, Daniel Rhodes, Deirdre Trainor, Dawn Holmes, Paula Southwick
Marna R Greenberg DO, MPH, FACEP
OBJECTIVES: To compare emergency department TnI serial sampling intervals, determine optimal diagnostic thresholds, and report representative diagnostic performance characteristics for early rule-in and rule-out of MI. METHODS: We prospectively measured TnI (AccuTnI+3™, Beckman Coulter) at serial time intervals in 1929 subjects with chest pain or equivalent ischemic symptoms suggestive of acute coronary syndromes at 14 medical centers. Diagnosis was adjudicated by an independent central committee. RESULTS: TnI ≥0.03ng/mL provided 96.0% sensitivity and 89.4% specificity at 1-3h after admission, and 94.9% sensitivity and 86.7% specificity at 3-6h. NPV (rule-out, non-MI) was 99.5% at 1-3h, and 99.0% at 3-6h when TnI is …
General Practitioners' Use Of Different Cardiovascular Risk Assessment Strategies: A Qualitative Study, Carissa Bonner, Jesse Jansen, Shannon Mckinn, Les Irwig, J. Doust, Paul Glasziou, Andrew Hayen, Kirsten Mccaffery
General Practitioners' Use Of Different Cardiovascular Risk Assessment Strategies: A Qualitative Study, Carissa Bonner, Jesse Jansen, Shannon Mckinn, Les Irwig, J. Doust, Paul Glasziou, Andrew Hayen, Kirsten Mccaffery
Jenny Doust
Objectives: To identify factors that influence the extent to which general practitioners use absolute risk (AR) assessment in cardiovascular disease (CVD) risk assessment. Design, setting and participants: Semi-structured interviews with 25 currently practising GPs from eight Divisions of General Practice in New South Wales, Australia, between October 2011 and May 2012. Data were analysed using framework analysis. Results: The study identified five strategies that GPs use with patients in different situations, defined in terms of the extent to which AR was used and the reasons given for this: the AR-focused strategy, used when AR assessment was considered useful for the …
Comparison Of Insulin Infusion Protocols Targeting 110-140 Mg/Dl In Patients After Cardiac Surgery., Vasudev Magaji, Shriddha Nayak, Amy Donihi, Lauren Willard, Srinivasa Jampana, Parachur Nivedita, Raymond Eder, Jann Johnston, Mary Korytkowski
Comparison Of Insulin Infusion Protocols Targeting 110-140 Mg/Dl In Patients After Cardiac Surgery., Vasudev Magaji, Shriddha Nayak, Amy Donihi, Lauren Willard, Srinivasa Jampana, Parachur Nivedita, Raymond Eder, Jann Johnston, Mary Korytkowski
Vasudev G Magaji MD, MS
BACKGROUND: Continuous intravenous insulin infusion (CII) following coronary artery bypass graft (CABG) surgery reduces postoperative complications and hospitalization duration. Because of limited data evaluating outcomes of CII with revised glycemic targets (110-140 mg/dL) in cardiac surgery, this study compared efficacy and safety of two different CII protocols having revised targets. SUBJECTS AND METHODS: This is a retrospective study comparing two different protocols between August 2009 and March 2010. Protocol 1 consists of four algorithms, and Protocol 2 is a table to adjust CII. Blood glucose (BG) and CII rates were recorded for 48 h postoperatively or CII discontinuation. Efficacy was …
Efficacy And Safety Of Continuous Insulin Infusion Protocols With Glycemic Targets Of 110-140 Mg/Dl In Patients With And Without Diabetes Following Cardiac Surgery, Shriddha Nayak, Vasudev Magaji, Amy Donihi, Lauren Willard, Srinivasa Jampana, Parachur Nivedita, Raymond Eder, Jann Johnston, Mary Korytkowski
Efficacy And Safety Of Continuous Insulin Infusion Protocols With Glycemic Targets Of 110-140 Mg/Dl In Patients With And Without Diabetes Following Cardiac Surgery, Shriddha Nayak, Vasudev Magaji, Amy Donihi, Lauren Willard, Srinivasa Jampana, Parachur Nivedita, Raymond Eder, Jann Johnston, Mary Korytkowski
Vasudev G Magaji MD, MS
No abstract provided.
Simultaneous Very Late Angiographic Stent Thrombosis Of 2 Drug-Eluting Stents: A Case Report, Joseph Quercia, Bryan Kane, Kathleen Kane
Simultaneous Very Late Angiographic Stent Thrombosis Of 2 Drug-Eluting Stents: A Case Report, Joseph Quercia, Bryan Kane, Kathleen Kane
Kathleen E Kane MD
No abstract provided.
Angiographic Recognition Of Ostial Left Main Coronary Artery Stenosis: Case Report., R M Macmillan, Bruce Feldman, V Maranhao
Angiographic Recognition Of Ostial Left Main Coronary Artery Stenosis: Case Report., R M Macmillan, Bruce Feldman, V Maranhao
Bruce A. Feldman DO
Ostial left main coronary stenosis has a poor prognosis and increased mortality rate with coronary arteriography. Due to its anatomic location, visualization of the stenosis may be difficult. A high index of suspicion based upon only a few signs should prompt the physician to perform certain maneuvers to obtain the correct diagnosis. Four illustrative cases are presented and discussed.
Long Term Stemi Outcome Data Acquisition, Tina Ruhf Rn, Orlando E. Rivera Rn, Nainesh C. Patel Md, Bruce Feldman Do, J Patrick Kleaveland Md, Mercedes Rios-Scott Bs, Kevin T. Whalen Bs, Susan Bernhard Bs, David A. Cox Md
Long Term Stemi Outcome Data Acquisition, Tina Ruhf Rn, Orlando E. Rivera Rn, Nainesh C. Patel Md, Bruce Feldman Do, J Patrick Kleaveland Md, Mercedes Rios-Scott Bs, Kevin T. Whalen Bs, Susan Bernhard Bs, David A. Cox Md
Bruce A. Feldman DO
No abstract provided.
Mi Alert St-Segment Elevation Myocardial Infarction (Stemi) Real Time Data Feedback: A Patient Quality Of Care Initiative, Orlando Rivera, Nainesh Patel, Bruce Feldman
Mi Alert St-Segment Elevation Myocardial Infarction (Stemi) Real Time Data Feedback: A Patient Quality Of Care Initiative, Orlando Rivera, Nainesh Patel, Bruce Feldman
Bruce A. Feldman DO
No abstract provided.
Left Atrial Enlargement Is Associated With Postoperative Respiratory Failure And Mortality, Bertrand N. Mukete Md, Christina Dunbar Do, Mph, Matthew M. Miller Do, Sherrine Eid Mph, Bruce Feldman Do
Left Atrial Enlargement Is Associated With Postoperative Respiratory Failure And Mortality, Bertrand N. Mukete Md, Christina Dunbar Do, Mph, Matthew M. Miller Do, Sherrine Eid Mph, Bruce Feldman Do
Bruce A. Feldman DO
No abstract provided.
One Year Outcomes Of A Pre-Hospital Myocardial Infarction Alert 3 Process, Gerald Coleman Do, Andrew C. Miller Do, David Richardson Md, David A. Cox Md, Nainesh Patel Md, J Patrick Kleaveland Md, Bruce Feldman Do, Ron Freudenberger Md, Richard S. Mackenzie Md
One Year Outcomes Of A Pre-Hospital Myocardial Infarction Alert 3 Process, Gerald Coleman Do, Andrew C. Miller Do, David Richardson Md, David A. Cox Md, Nainesh Patel Md, J Patrick Kleaveland Md, Bruce Feldman Do, Ron Freudenberger Md, Richard S. Mackenzie Md
Bruce A. Feldman DO
No abstract provided.
Impact Of Pre-Hospital Myocardial Infarction Alert Process Education On Door To Balloon Times At Sites Within A Regional Heart Center, Gerald Coleman Do, Andrew C. Miller Do, David Richardson Md, David Cox Md, Nainesh C. Patel Md, J Patrick Kleaveland Md, Bruce Feldman Do, Ron Freudenberger Md, Richard S. Mackenzie Md
Impact Of Pre-Hospital Myocardial Infarction Alert Process Education On Door To Balloon Times At Sites Within A Regional Heart Center, Gerald Coleman Do, Andrew C. Miller Do, David Richardson Md, David Cox Md, Nainesh C. Patel Md, J Patrick Kleaveland Md, Bruce Feldman Do, Ron Freudenberger Md, Richard S. Mackenzie Md
Bruce A. Feldman DO
No abstract provided.
Rapid Door To Balloon Time In The Treatment Of Acute St- Elevation Myocardial Infarction Meaningfully Reduces Overall Hospital Stay, Amit N. Nanavati Md, Nainesh Patel Md, Bruce Feldman Do, J Patrick Kleaveland Md, Orlando E. Rivera Rn, David A. Cox Md
Rapid Door To Balloon Time In The Treatment Of Acute St- Elevation Myocardial Infarction Meaningfully Reduces Overall Hospital Stay, Amit N. Nanavati Md, Nainesh Patel Md, Bruce Feldman Do, J Patrick Kleaveland Md, Orlando E. Rivera Rn, David A. Cox Md
Bruce A. Feldman DO
No abstract provided.
Radiofrequency Ablation Improving Lv Function In Cardiomyopathy Secondary To Low Burden Of Premature Ventricular Complexes, Nasir Shariff, Daniel Makowski, Vadim Levin
Radiofrequency Ablation Improving Lv Function In Cardiomyopathy Secondary To Low Burden Of Premature Ventricular Complexes, Nasir Shariff, Daniel Makowski, Vadim Levin
Vadim A Levin MD
No abstract provided.
Addressing The Controversy Of Rate-Versus-Rhythm Control In Atrial Fibrillation, Tahmeed Contractor, Vadim Levin, Ravi Desai, Francis E Marchlinski
Addressing The Controversy Of Rate-Versus-Rhythm Control In Atrial Fibrillation, Tahmeed Contractor, Vadim Levin, Ravi Desai, Francis E Marchlinski
Vadim A Levin MD
Atrial fibrillation is the most common sustained cardiac arrhythmia and significantly increases patient risk of stroke, cardiomyopathy, and mortality. Rate versus rhythm control as the "best" treatment strategy remains an issue of considerable, ongoing debate. A multitude of clinical trials have compared the 2 strategies and have not shown any benefit of one approach over the other. However, the trials were conducted in specific subgroups of patients and demonstrated low success rates with antiarrhythmic drug (AAD) therapy and a high incidence of adverse AAD effects. Sub-analyses of the trials have confirmed that successful rhythm control with sinus rhythm restoration is …
Addressing The Controversy Of Rate-Versus-Rhythm Control In Atrial Fibrillation, Tahmeed Contractor, Vadim Levin, Ravi Desai, Francis E Marchlinski
Addressing The Controversy Of Rate-Versus-Rhythm Control In Atrial Fibrillation, Tahmeed Contractor, Vadim Levin, Ravi Desai, Francis E Marchlinski
Ravi V Desai MD
Atrial fibrillation is the most common sustained cardiac arrhythmia and significantly increases patient risk of stroke, cardiomyopathy, and mortality. Rate versus rhythm control as the "best" treatment strategy remains an issue of considerable, ongoing debate. A multitude of clinical trials have compared the 2 strategies and have not shown any benefit of one approach over the other. However, the trials were conducted in specific subgroups of patients and demonstrated low success rates with antiarrhythmic drug (AAD) therapy and a high incidence of adverse AAD effects. Sub-analyses of the trials have confirmed that successful rhythm control with sinus rhythm restoration is …
Cardiopulmonary Resuscitation Prescription Program: A Pilot Randomized Comparator Trial, Marna Greenberg, Gavin Barr, Valerie Rupp, Nainesh Patel, Kevin Weaver, Kimberly Hamilton, James Reed
Cardiopulmonary Resuscitation Prescription Program: A Pilot Randomized Comparator Trial, Marna Greenberg, Gavin Barr, Valerie Rupp, Nainesh Patel, Kevin Weaver, Kimberly Hamilton, James Reed
Marna R Greenberg DO, MPH, FACEP
No abstract provided.
Gender Disparity In Non St Elevation Myocardial Infarction Cardiac Care: A Unique Illustration, Marna Greenberg, R Llaguri, Monisha Bindra, Valerie Rupp, Sharon Kimmel, William Bond, Richard Mackenzie
Gender Disparity In Non St Elevation Myocardial Infarction Cardiac Care: A Unique Illustration, Marna Greenberg, R Llaguri, Monisha Bindra, Valerie Rupp, Sharon Kimmel, William Bond, Richard Mackenzie
Marna R Greenberg DO, MPH, FACEP
No abstract provided.
Gender Differences In Acute Cardiac Care: Where It’S Not, Marna Greenberg, Richard Mackenzie, David Richardson, Michael Rossi, Valerie Rupp, Anne Crown, Sharon Kimmel
Gender Differences In Acute Cardiac Care: Where It’S Not, Marna Greenberg, Richard Mackenzie, David Richardson, Michael Rossi, Valerie Rupp, Anne Crown, Sharon Kimmel
Marna R Greenberg DO, MPH, FACEP
No abstract provided.