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Full-Text Articles in Medicine and Health Sciences
Impact Of Parent’S Hiv Status On Their Uninfected Child—A Comparative Analysis Of The Child’S Healthcare Utilization, Access And Health Outcomes, Arijit Ganguli
Impact Of Parent’S Hiv Status On Their Uninfected Child—A Comparative Analysis Of The Child’S Healthcare Utilization, Access And Health Outcomes, Arijit Ganguli
Theses and Dissertations (ETD)
With the advent of effective antiretroviral medication and increased expectancy of life span among HIV-infected individuals has lead to an increase in the at-risk population of uninfected children living with their HIV-infected parent(s). The purpose of this study was to investigate the impact of parent’s HIV status on their child’s access to healthcare resources, healthcare utilization and health outcomes.
This was a cross-sectional study in which the information on the children of HIV seropositive parent(s) was collected through a face-to-face interview of the HIV-infected parents having children currently residing with them. The comparative group comprising of children of HIV seronegative …
Contribution Of The Membrane-Proximal Region Of The Vesicular Stomatitis Virus Glycoprotein To Host Cell Entry And Membrane Fusion, Elizabeth Lane Matheny
Contribution Of The Membrane-Proximal Region Of The Vesicular Stomatitis Virus Glycoprotein To Host Cell Entry And Membrane Fusion, Elizabeth Lane Matheny
Theses and Dissertations (ETD)
Vesicular stomatitis virus (VSV) is an enveloped, nonsegmented, negative-sense, RNA virus belonging to the Rhabdoviridae family. VSV is considered the prototypic Rhabdovirus due to its simple genetic organization, broad host cell tropism, and ability to be easily grown in cell culture. Therefore, VSV has been used as the prototype to study viral entry, transcription, replication, and assembly. Viral entry, a critical step in the lifecycle of the virus, is mediated by the outer surface protein, G and will be the focus of this dissertation.
We hypothesize that the highly conserved residues in the membrane-proximal region of VSV G protein are …
Pandemic Potential Of Reassortant Swine Influenza A Viruses, Christy Brockwell Staats
Pandemic Potential Of Reassortant Swine Influenza A Viruses, Christy Brockwell Staats
Theses and Dissertations (ETD)
Influenza A viruses are capable of causing disease in several species, including birds, humans and swine. Host specificity of the viruses is not absolute, and is influenced by a range of factors. Swine play a pivotal role in the interspecies transmission of influenza A viruses, as they are susceptible to infection with both human and avian strains and have been implicated as a “mixing vessel” for the reassortment of influenza A viruses from different species. The reassortment of influenza A viruses of human and avian origin led to human influenza pandemics in 1957 and 1968.
The dynamics of swine influenza …