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Full-Text Articles in Medicine and Health Sciences
The Effect Of Aging On The Immune Response To Vaccination In The Horse, Daniel H. Fermaglich
The Effect Of Aging On The Immune Response To Vaccination In The Horse, Daniel H. Fermaglich
LSU Master's Theses
Vaccination programs are designed to protect an animal from infection, however, depending upon the age and health of the animal vaccination may not stimulate a protective humoral response. It is possible that, as in the human and mouse models, geriatric equines may be less responsive than their younger counterparts to current vaccination protocols. The purpose of this study was to identify an age related diminution in the primary and secondary immune responses of geriatric horses in response to vaccination. Two groups of horses were sampled. The first group consisted of an open herd of 39 privately owned horses, varying in …
Equine Immunity To Cyathostome Infections, Marie Alexandra Baudena
Equine Immunity To Cyathostome Infections, Marie Alexandra Baudena
LSU Doctoral Dissertations
To study the protective responses of cyathostome-infected ponies, two challenges were performed employing animals with different histories of exposure to these parasites. The hypothesis developed and to be tested in these experiments was that ponies that had longer exposure to cyathostome contaminated pastures would express acquired resistance to infection. The assumption behind this hypothesis was that helminth-naïve ponies infected with cyathostomes would eliminate the infection using only innate immune responses. Whereas previously exposed ponies would eliminate the infection with acquired immune responses, and these would be more effective in ponies with longer exposure to cyathostomes. Thus, helminth-naïve animals would acquire …